Multiple inositol polyphosphate phosphatase 1 is an enzyme that in humans is encoded by the MINPP1 gene.[1][2]

MINPP1 hydrolyzes the abundant metabolites inositol pentakisphosphate and inositol hexakisphosphate and, like PTEN (MIM 601728), has the ability to remove 3-phosphate from inositol phosphate substrates.[supplied by OMIM][2]

References

  1. ^ Chi H, Tiller GE, Dasouki MJ, Romano PR, Wang J, O'keefe RJ, Puzas JE, Rosier RN, Reynolds PR (May 1999). "Multiple inositol polyphosphate phosphatase: evolution as a distinct group within the histidine phosphatase family and chromosomal localization of the human and mouse genes to chromosomes 10q23 and 19". Genomics. 56 (3): 324–36. doi:10.1006/geno.1998.5736. PMID 10087200
  2. ^ "Entrez Gene: MINPP1 multiple inositol polyphosphate histidine phosphatase, 1"

Further reading

  • Romano PR, Wang J, O'Keefe RJ, etal (1998). "HiPER1, a phosphatase of the endoplasmic reticulum with a role in chondrocyte maturation". J. Cell Sci.. 111 (6): 803–13. doi:10.1242/jcs.111.6.803. PMID 9472008
  • Caffrey JJ, Hidaka K, Matsuda M, etal (1999). "The human and rat forms of multiple inositol polyphosphate phosphatase: functional homology with a histidine acid phosphatase up-regulated during endochondral ossification". FEBS Lett.. 442 (1): 99–104. doi:10.1016/S0014-5793(98)01636-6. PMID 9923613. S2CID 7105717
  • Chi H, Yang X, Kingsley PD, etal (2000). "Targeted deletion of Minpp1 provides new insight into the activity of multiple inositol polyphosphate phosphatase in vivo". Mol. Cell. Biol.. 20 (17): 6496–507. doi:10.1128/MCB.20.17.6496-6507.2000. PMC 86124. PMID 10938126
  • Wiemann S, Weil B, Wellenreuther R, etal (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res.. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166
  • Gimm O, Chi H, Dahia PL, etal (2001). "Somatic mutation and germline variants of MINPP1, a phosphatase gene located in proximity to PTEN on 10q23.3, in follicular thyroid carcinomas". J. Clin. Endocrinol. Metab.. 86 (4): 1801–5. doi:10.1210/jcem.86.4.7419. PMID 11297621
  • VanHouten JN, Asch HL, Asch BB (2001). "Cloning and characterization of ectopically expressed transcripts for the actin-binding protein MIPP in mouse mammary carcinomas". Oncogene. 20 (38): 5366–72. doi:10.1038/sj.onc.1204701. PMID 11536049. S2CID 6474518
  • Strausberg RL, Feingold EA, Grouse LH, etal (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A.. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932
  • Clark HF, Gurney AL, Abaya E, etal (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res.. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309
  • Deloukas P, Earthrowl ME, Grafham DV, etal (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. Bibcode:2004Natur.429..375D. doi:10.1038/nature02462. PMID 15164054
  • Gerhard DS, Wagner L, Feingold EA, etal (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res.. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334
  • Liu T, Qian WJ, Gritsenko MA, etal (2006). "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry". J. Proteome Res.. 4 (6): 2070–80. doi:10.1021/pr0502065. PMC 1850943. PMID 16335952
  • Kimura K, Wakamatsu A, Suzuki Y, etal (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res.. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560