'''Lesson No.1''' or '''Lesson 1''' or '''Lesson One''' may refer to:
* ''Lesson 1'', a music mix by Double Dee and Steinski *''Lesson 1'', a 2013 album by E-girls *''Lesson 1'' (Red Warriors album), 1986 *''Lesson One: Misanthropy!'', an album by Death in June *''Lesson No. 1'', a 1980 Glenn Branca EP *''Lesson No.1'', a 2006 sampler album by Imperial Recordings *"Lesson One", a 1962 single by Russ Conway *"Lesson No.1", a song by Viva Voce from The Heat Can Melt Your Brain *"Lesson #1", a song by Anthony Rapp from ''Look Around''
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