LacED

{{Short description|Biological database}} {{Infobox biodatabase|title=The Lactase Engineering Database|logo=|description=Database of Beta-lactamases that allows reconciliation of TEM Beta-lactamase information against NCBI|scope=Beta-lactamase|organism=Bacteria|center=|laboratory=|author=|pmid=19698099|released=|standard=|format=|url={{URL|http://www.laced.uni-stuttgart.de/}}|download=|webservice=|sql=|sparql=|webapp=|standalone=|license=|versioning=|frequency=|curation=|bookmark=yes|version=}}'''LacED''', also known as '''The Lactamase Engineering Database''', is a database that identifies and corrects inconsistencies in already existing databases, namely Beta-lactamases. It integrates such information as mutations, sequence alignments, and structures in order to accomplish the task.<ref name=":0">{{Cite journal|last1=Thai|first1=Quan|last2=Bös|first2=Fabian|last3=Pleiss|first3=Jürgen|date=2009|title=The Lactamase Engineering Database: a critical survey of TEM sequences in public databases|url= |journal=BMC Genomics|language=en|volume=10|issue=1|pages=390|doi=10.1186/1471-2164-10-390|pmid=19698099|issn=1471-2164|pmc=2742552 |doi-access=free }}</ref> As of the publication of the primary literature, LacED provides 2399 sequences entries and 37 structure entries.<ref name=":0" /> Example of this database in action is shown when 89 proteins from the microbial organisms and 35 proteins from cloning or expression vectors had new mutation profiles.<ref name=":0" /> Additionally, 55 proteins had inconsistent annotations in their TEM assignments or mutation profiles.<ref name=":0" />

== See also ==

* Antimicrobial resistance databases

== References == {{Reflist}}

Category:Antimicrobial resistance organizations Category:Biological databases