Jeffrey V. Ravetch

{{Use mdy dates|date=July 2023}} {{Infobox scientist | name = | image = | birth_date = 1951  | birth_place = | death_date = | death_place = | death_cause = | citizenship = | nationality = | fields = | workplaces = {{plainlist| * Memorial Sloan-Kettering Cancer Center * Rockefeller University }} | education = | alma_mater = {{plainlist| * Yale University * Rockefeller University * Cornell University Medical School }} | known_for = | awards = Wolf Prize in Medicine | spouse = Wendy Evans Joseph<ref name="Wedding2001NYTimes">{{Cite news|url=https://www.nytimes.com/2001/10/28/style/wedding-wendy-joseph-jeffrey-ravetch.html|title=WEDDING; Wendy Joseph, Jeffrey Ravetch|work=The New York Times |date=October 28, 2001|via=NYTimes.com}}</ref> | children = }} '''Jeffrey Victor Ravetch''' (born 1951) is a professor and head of the Laboratory of Molecular Genetics and Immunology at The Rockefeller University.

==Background and training== Ravetch earned his B.S. degree at Yale University in 1973 in molecular biophysics and biochemistry working with Donald Crothers on the thermodynamic and kinetic properties of synthetic oligoribonucleotides. He received a Ph.D. from The Rockefeller University in 1978 in bacterial genetics working in the laboratory of Norton Zinder and Peter Model in the Laboratory of Genetics at Rockefeller and an M.D. from Cornell University Medical School in 1979. He completed postdoctoral studies at the National Institutes of Health with Philip Leder, where he identified and characterized the genes for human antibodies and the DNA elements involved in switch recombination. From 1982 to 1996 Dr. Ravetch was a member of the faculty of Memorial Sloan-Kettering Cancer Center and Cornell Medical College. Currently, Ravetch is the Theresa and Eugene M. Lang Professor in the Leonard Wagner Laboratory of Molecular Genetics and Immunology at The Rockefeller University.<ref>{{cite web|url=http://www.rockefeller.edu/research/faculty/abstract.php?id=141|title=The Rockefeller University » Scientists & Research|work=rockefeller.edu|accessdate=February 12, 2015|archive-url=https://web.archive.org/web/20150219050923/http://www.rockefeller.edu/research/faculty/abstract.php?id=141|archive-date=February 19, 2015|url-status=dead}}</ref><ref>{{cite journal|title=Profile of Jeffrey Ravetch| pmc=2683121 | pmid=19416845 | doi=10.1073/pnas.0903830106| volume=106| date=May 2009| author=Ravetch J| journal=Proc. Natl. Acad. Sci. U.S.A.| issue=19 | pages=7689–91| bibcode=2009PNAS..106.7689D | doi-access=free }}</ref><ref>{{cite web|url=http://www.biotechniques.com/BiotechniquesJournal/2008/February/Profile-of-Jeffrey-V.-Ravetch-M.D.-Ph.D./biotechniques-44993.html?autnID=506297|title=BioTechniques – Profile of Jeffrey V. Ravetch, M.D., Ph.D.|work=biotechniques.com|accessdate=February 12, 2015}}</ref><ref>{{Cite web|url=https://www.bloomberg.com/markets/stocks|title=Stocks|website=Bloomberg.com|date=July 17, 2023 }}</ref><ref>{{Cite web|url=http://www.cancerresearch.org/about/scientific-advisory-council/jeffrey-ravetch|title=CRI Profile|access-date=February 12, 2015|archive-date=April 2, 2015|archive-url=https://web.archive.org/web/20150402122902/http://www.cancerresearch.org/about/scientific-advisory-council/jeffrey-ravetch|url-status=dead}}</ref><ref>{{Cite web|url=https://centennial.rucares.org/index.php?page=New_Paradigm_Immunology|title=The Rockefeller University » Hospital Centennial|website=centennial.rucares.org}}</ref>

==Summary of research achievements== Ravetch revealed the mechanisms by which antibodies mediate and regulate their diverse in vivo effector functions through the characterization of the structural and functional diversity of the Fc region and their interactions with the family of Fc receptors he defined. His studies have focused on the redesign of antibodies to enhance their therapeutic capacity for the treatment of infectious, neoplastic and inflammatory diseases.

==Awards== * William B. Coley Award, Cancer Research Institute, 2007 * Gairdner International Award, 2012<ref>{{cite web|url=http://www.gairdner.org/content/jeffrey-v-ravetch|title=Jeffrey V. Ravetch – Gairdner|work=gairdner.org|accessdate=February 12, 2015|archive-url=https://web.archive.org/web/20160904235305/http://www.gairdner.org/content/jeffrey-v-ravetch|archive-date=September 4, 2016|url-status=dead}}</ref><ref>{{Cite web |url=http://newswire.rockefeller.edu/2012/03/21/jeffrey-v-ravetch-and-michael-w-young-to-receive-canada-gairdner-international-awards/ |title=Report on Gairdner Award |access-date=February 12, 2015 |archive-url=https://web.archive.org/web/20150315070751/http://newswire.rockefeller.edu/2012/03/21/jeffrey-v-ravetch-and-michael-w-young-to-receive-canada-gairdner-international-awards/ |archive-date=March 15, 2015 |url-status=dead }}</ref><ref>{{Cite web|url=http://www.asbmb.org/asbmbtoday/asbmbtoday_article.aspx?id=16659|title=ASBMB Article on Gairdner|access-date=February 12, 2015|archive-date=March 4, 2016|archive-url=https://web.archive.org/web/20160304195656/http://www.asbmb.org/asbmbtoday/asbmbtoday_article.aspx?id=16659|url-status=dead}}</ref> * Sanofi-Institut Pasteur Award, 2012,<ref>{{Cite web|url=http://www.pasteur.fr/ip/easysite/pasteur/en/research/scientific-communication/conferences-and-scientific-congress/conferences-services-colloques/sanofi/the-4--award-winners-2012|title=Sanofi Prize}}</ref> * Honorary Doctorate, Friedrich-Alexander-University Erlangen-Nürnberg, 2013<ref name="Friedrich-Alexander-Universität Erlangen-Nürnberg › Friedrich-Alexander-Universität Erlangen-Nürnberg 2023 l044">{{cite web | title=Honorary doctorates › Friedrich-Alexander-Universität Erlangen-Nürnberg | website=Friedrich-Alexander-Universität Erlangen-Nürnberg | date=17 July 2023 | url=https://www.fau.eu/fau/successes-and-honorary-academic-titles/honorary-doctorates/ | access-date=17 July 2023}}</ref> * Wolf Prize in Medicine, 2015<ref>{{cite web|url=http://212.199.115.173/~wolf/index.php?dir=site&page=winners&cs=815|title=פרופ' ג'פרי ראבץ', Jeffrey Ravetch|author=Simply-Smart|work=115.173|accessdate=February 12, 2015|archive-date=May 19, 2018|archive-url=https://web.archive.org/web/20180519042349/http://212.199.115.173/~wolf/index.php?dir=site&page=winners&cs=815|url-status=dead}}</ref><ref>{{Cite web |url=http://newswire.rockefeller.edu/2015/02/02/jeffrey-ravetch-wins-wolf-prize-in-medicine/ |title=Report on Wolf Prize |access-date=February 12, 2015 |archive-url=https://web.archive.org/web/20150206050248/http://newswire.rockefeller.edu/2015/02/02/jeffrey-ravetch-wins-wolf-prize-in-medicine/ |archive-date=February 6, 2015 |url-status=dead }}</ref><ref>{{Cite web|url=https://www.jpost.com/israel-news/health/wolf-prizes-in-the-sciences-and-arts-presented-to-nine-north-americans-389466|title=Wolf Prizes in the sciences and arts presented to nine North Americans|website=The Jerusalem Post | JPost.com}}</ref> * Ross Prize in Molecular Medicine, 2017<ref>{{Cite web|url=https://feinstein.northwell.edu/|title=Feinstein Institutes for Medical Research | Northwell Health|website=feinstein.northwell.edu}}</ref> * Robert Koch Medal and Award, 2018<ref>{{Cite web|url=https://www.robert-koch-stiftung.de/index.php?article_id=15&clang=1|title=Robert Koch Stiftung – Robert Koch Award|website=www.robert-koch-stiftung.de|access-date=May 1, 2021|archive-date=February 1, 2019|archive-url=https://web.archive.org/web/20190201013319/https://www.robert-koch-stiftung.de/index.php?article_id=15&clang=1|url-status=dead}}</ref>

===Memberships=== * National Academy of Sciences, 2006<ref name="National Academy of Sciences 2021 n321">{{cite web | title=Jeffrey Ravetch | website=National Academy of Sciences | date=10 June 2021 | url=http://www.nasonline.org/member-directory/members/20000227.html | access-date=17 July 2023}}</ref> * Institute of Medicine, 2007<ref name="News 2007 v731">{{cite web | title=Jeffrey Ravetch elected to Institute of Medicine | website=Rockefeller | date=8 October 2007 | url=https://www.rockefeller.edu/news/2566-jeffrey-ravetch-elected-to-institute-of-medicine/ | access-date=17 July 2023}}</ref>

==References== {{reflist|30em}}

{{Authority control}} {{DEFAULTSORT:Ravetch, Jeffrey V.}} Category:1951 births Category:Living people Category:American immunologists Category:Rockefeller University faculty Category:Yale University alumni Category:Rockefeller University alumni Category:Weill Cornell Medical College alumni Category:Members of the National Academy of Medicine