James Jorgenson

{{Infobox scientist | name = James W Jorgenson | native_name = | native_name_lang = | image = Jorgenson, James.jpg | alt = | caption = | birth_name =  | birth_date = September 9, 1952 | birth_place = Kenosha, Wisconsin | other_names = | residence = | citizenship = | nationality = | fields = Analytical Separations, Capillary Electrophoresis, Capillary Liquid Chromatography | workplaces = University of North Carolina at Chapel Hill | patrons = | alma_mater = | thesis_title =  | thesis_url =  | thesis_year =  | doctoral_advisor =  Milos Novotny | academic_advisors = | notable_students = | known_for = | author_abbrev_bot = | author_abbrev_zoo = | influences = | influenced = | awards = | signature =  | signature_alt = | website =  | footnotes = | spouse =  | honorific_prefix = | honorific_suffix = | image_upright = | pronounce = | education = Northern Illinois University (1970–1974; B.S., 1974) Indiana University (1974–1979; Ph.D., 1979) | partner =  }}

'''James Wallace Jorgenson''' is an American academic who previously held the position of William Rand Kenan Jr. Distinguished Professor of Chemistry at UNC-Chapel Hill.<ref>{{Cite news|url=https://chem.unc.edu/faculty/Jorgenson-James/|title=Jorgenson, James – Department of Chemistry|work=Department of Chemistry|access-date=2018-10-19}}{{Dead link|date=August 2025 |bot=InternetArchiveBot |fix-attempted=yes }}</ref> He is best known for his work developing capillary zone electrophoresis,<ref>{{Cite web|url=https://theanalyticalscientist.com/power-list/the-power-list-2013/12-james-w-jorgenson/|title=#12 James W. Jorgenson|website=The Analytical Scientist|access-date=2018-10-30}}</ref> and is a member of the American Academy of Arts and Sciences.<ref name=":0">{{Cite web|url=https://www.amacad.org/contentu.aspx?d=941|title=Book of Members – American Academy of Arts & Sciences|website=www.amacad.org|access-date=2018-10-30|archive-url=https://web.archive.org/web/20140830050459/https://www.amacad.org/contentu.aspx?d=941|archive-date=2014-08-30|url-status=dead}}</ref>

==Early life and education== Jorgenson was born on September 9, 1952, in Kenosha, Wisconsin.<ref>{{Cite journal|date=2008-11-30|title=Jorgenson, James Wallace|url=http://link.galegroup.com/apps/doc/CX3004657286/GVRL?sid=GVRL&xid=4ffdf577|journal=American Men & Women of Science|language=English|volume=4}}</ref> He received a Bachelor of Science degree in chemistry from Northern Illinois University in 1974 and a PhD in chemistry from Indiana University in 1979.<ref>{{Cite journal|last1=Grinias|first1=James P.|last2=Kennedy|first2=Robert T.|date=November 2017|title=Pushing the boundaries of chromatography and electrophoresis—Honoring James Jorgenson on his 65th birthday|journal=Journal of Chromatography A|volume=1523|pages=1–2|doi=10.1016/j.chroma.2017.08.027|pmid=28823782|issn=0021-9673}}</ref>

== Research interests == Jorgenson's research group is focused on utilizing analytical separation techniques to solve research problems in complex mixture analysis. The group currently focuses on ultra-high pressure capillary liquid chromatography combined with mass spectrometry (MS).

Jorgenson's research group is best known for their breakthrough in the field of separation sciences, the invention of capillary electrophoresis (CE).<ref>Zone Electrophoresis in Open-Tubular Glass Capillaries, J.W. Jorgenson, and K.D. Lukacs, Analytical Chemistry, '''53''', 1298-1302 (1981).</ref><ref>Capillary Zone Electrophoresis, J.W. Jorgenson, and K.D. Lukacs, Science, '''222''', 266-272 (1983).</ref> He began his research at UNC Chapel Hill studying electro-osmotically driven chromatography. The development of CE has aided in the advancement of many fields of science, including DNA sequencing, forensic DNA analysis and analysis of intact proteins. CE technology enabled completion of the sequencing of the human genome far ahead of the expected schedule and far below anticipated cost.<ref name="Dovichi Zhang pp. 4463–4468">{{cite journal | last1=Dovichi | first1=Norman J. | last2=Zhang | first2=Jianzhong | title=How Capillary Electrophoresis Sequenced the Human Genome | journal=Angewandte Chemie International Edition | publisher=Wiley | volume=39 | issue=24 | date=15 December 2000 | issn=1433-7851 | doi=10.1002/1521-3773(20001215)39:24<4463::aid-anie4463>3.0.co;2-8 | pages=4463–4468| pmid=11169637 | doi-access=free }}</ref>

Jorgenson's research group is also notable for some of the earliest demonstrations of the analysis of the contents of single cells,<ref>Chemical Analysis of Single Neurons by Open Tubular Liquid Chromatography, R.T. Kennedy, R.L. St Claire III, J.G. White, and J.W. Jorgenson, Microchimica Acta, 1987 (II), 37-45 (1988).</ref><ref>Quantitative Analysis of Individual Neurons by Open Tubular Liquid Chromatography with Voltammetric detection, R.T. Kennedy and J.W. Jorgenson, Anal. Chem., '''61''', 436-441 (1989).</ref> comprehensive two-dimensional separations,<ref>Automated Instrument for Comprehensive Two-Dimensional High- Performance Liquid Chromatography of Proteins, M.M. Bushey and J.W. Jorgenson, Anal. Chem., '''62''', 161-167 (1990).</ref><ref>Automated Instrument for Comprehensive Two-Dimensional High Performance Liquid Chromatography-Capillary Zone Electrophoresis, M.M. Bushey and J.W. Jorgenson, Anal. Chem., '''62''', 978-984 (1990).</ref> and the invention of ultra-high pressure liquid chromatography.<ref>Ultra High Pressure Reversed Phase Liquid Chromatography in Packed Capillary Columns, J.E. MacNair, K.C. Lewis, and J.W. Jorgenson, Anal. Chem., '''69,''' 983-989 (1997).</ref> His publications in separation methods have been extensively cited.<ref>{{Cite web|url=https://scholar.google.com/citations?user=nwKEiroAAAAJ&hl=en|title=JAMES JORGENSON – Google Scholar Citations|website=scholar.google.com|access-date=2018-10-30}}</ref>

Jorgenson retired in 2019 from the University of North Carolina at Chapel Hill.<ref>{{Cite web|title=Jim Jorgenson Symposium – Innovate Carolina|url=https://innovate.unc.edu/event/jim-jorgenson-symposium/|access-date=2020-08-28|website=innovate.unc.edu|date=18 April 2019 }}</ref> He was awarded the American Chemical Society Award in Separations Science and Technology.<ref>{{Cite web|title=Jim Jorgenson receives 2021 ACS Award in Separation Science and Technology|url=https://chem.unc.edu/news/jim-jorgenson-receives-2021-acs-award-in-separation-science-and-technology/|access-date=2020-08-28|language=en-US}}</ref>

== Honors received ==

*American Chemical Society Award in Separations Science and Technology, 2021<ref>{{Cite web|title=Waters Corporation : The Science of What's Possible|url=https://www.waters.com/nextgen/us/en.html|access-date=2020-08-28|website=www.waters.com}}</ref> *Special issue of the "Journal of Chromatography A" honoring James Jorgenson, November 2017<ref>{{Cite web|url=https://www.sciencedirect.com/journal/journal-of-chromatography-a/vol/1523/suppl/C|title=ScienceDirect|website=www.sciencedirect.com|access-date=2018-10-30}}</ref> *Lifetime Achievement Award, LCGC Magazine North America, 2011<ref>{{Cite journal|url=http://www.chromatographyonline.com/james-jorgenson-ce-uhplc-and-future-lc|title=James Jorgenson on CE, UHPLC, and the Future of LC|last=LGC Editors|date=April 13, 2011|website=chromatographyonline.com|series=E-Separation Solutions-04-14-2011 |archive-url=|archive-date=|url-status= |access-date=}}</ref> *American Chemical Society Award in Analytical Chemistry, 2007<ref>{{Cite web|url=https://www.acs.org/content/acs/en/funding-and-awards/awards/national/bytopic/acs-award-in-analytical-chemistry.html|title=ACS Award in Analytical Chemistry – American Chemical Society|website=American Chemical Society|access-date=2018-10-30}}</ref> * Elected Member of the American Academy of Arts and Sciences, 2007<ref name=":0" /> *Lifetime Achievement Award, LCGC Magazine Europe, 2006 *Special issue of the journal "Electrophoresis" dedicated to J. W. Jorgenson, October 2001 *American Chemical Society Award in Chromatography, 1993<ref>{{Cite web|url=https://www.acs.org/content/acs/en/funding-and-awards/awards/national/bytopic/acs-award-in-chromatography.html|title=ACS Award in Chromatography – American Chemical Society|website=American Chemical Society|access-date=2018-10-30}}</ref>

== Patents == * "Coaxial Flow Post Capillary Mixing", J.W. Jorgenson and D.J. Rose, U.S. Patent No. 4,936,974. * "Microelectrospray Method and Apparatus", J.W. Jorgenson and D.M. Dohmeier, U.S. Patent No. 5,115,131. * "Two-Dimensional High-Performance Liquid Chromatography/Capillary Electrophoresis", J.W. Jorgenson and M.M. Bushey, U.S. Patent No. 5,131,998. * "Two-Dimensional High-Performance Liquid Chromatography/Capillary Electrophoresis", J.W. Jorgenson and M.M. Bushey, U.S. Patent No. 5,240,577. * "Method and Device for High Speed Separation of Complex Molecules", J.W. Jorgenson and C.A. Monnig, U.S. Patent No. 5,269,900. * "Two-Dimensional Separation System", J.W. Jorgenson and A.V. Lemmo, U.S. Patent No. 5,389,221. * "Two-Dimensional Separation System", J.W. Jorgenson and A.V. Lemmo, U.S. Patent No. 5,496,460. * “Sample injector system for liquid chromatography”, Gerhardt; Geoff C., Jorgenson; James W., Fadgen; Keith, U.S. Patent No. 8,173,070

== References == {{reflist}}

{{DEFAULTSORT:Jorgenson, James}} Category:1952 births Category:Living people Category:21st-century American chemists Category:Indiana University alumni Category:Northern Illinois University alumni Category:People from Kenosha, Wisconsin Category:University of North Carolina at Chapel Hill faculty