Isono

'''Isono''' (written: 磯野) is a Japanese surname. Notable people with the surname include:

*{{Nihongo|Hiroo Isono|磯野 宏夫||1945–2013}}, Japanese painter and illustrator *{{Nihongo|Isono Kazumasa|磯野 員昌||1534–1583}}, Japanese samurai *{{Nihongo|Kiriko Isono|磯野 貴理子||born 1964}}, Japanese comedian, entertainer and actress *{{Nihongo|Isono Tamba-no-kami|磯野 丹波}}, Japanese samurai

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Category:Japanese-language surnames