{{Short description|Biological database}} {{Infobox biodatabase|title=Integrall|logo=|description=Database that collects and documents integrons and transposable elements conferring resistance.|scope=Integrons and other transposable elements|organism=Bacteria|center=|laboratory=|author=|pmid=19228805|released=|standard=|format=|url={{URL|http://integrall.bio.ua.pt}}|download=|webservice=|sql=|sparql=|webapp=|standalone=|license=|versioning=|frequency=|curation=|bookmark=yes|version=}}'''Integrall''' is a database that seeks to document and annotate integrons and all other transposable elements that confer resistance to antibiotics in bacteria.<ref name=":0">{{Cite journal|last1=Moura|first1=A.|last2=Soares|first2=M.|last3=Pereira|first3=C.|last4=Leitao|first4=N.|last5=Henriques|first5=I.|last6=Correia|first6=A.|date=2009-04-15|title=INTEGRALL: a database and search engine for integrons, integrases and gene cassettes|journal=Bioinformatics|volume=25|issue=8|pages=1096–1098|doi=10.1093/bioinformatics/btp105|pmid=19228805|s2cid=15350885|issn=1367-4803|doi-access=free}}</ref>
As of release 1.2, Integrall contains ~4800 integron sequences.<ref name=":0" /> Transposable elements and Integrons in bacteria are a major threat in the field of antimicrobial drug research because they allow bacteria to develop resistances through interbacterial interactions.<ref>{{Cite journal|last1=Sørensen|first1=Søren J.|last2=Bailey|first2=Mark|last3=Hansen|first3=Lars H.|last4=Kroer|first4=Niels|last5=Wuertz|first5=Stefan|date=September 2005|title=Studying plasmid horizontal transfer in situ: a critical review|journal=Nature Reviews Microbiology|volume=3|issue=9|pages=700–710|doi=10.1038/nrmicro1232|pmid=16138098|s2cid=39068141|issn=1740-1526}}</ref><ref name=":1">{{Cite journal|last1=Hentschel|first1=Ute|last2=Hacker|first2=Jörg|date=June 2001|title=Pathogenicity islands: the tip of the iceberg|journal=Microbes and Infection|volume=3|issue=7|pages=545–548|doi=10.1016/s1286-4579(01)01410-1|pmid=11418328|issn=1286-4579|doi-access=free}}</ref> They allow bacteria to develop resistances that they typically cannot.<ref name=":1" /> Thus, Integrall seeks to be a comprehensive and unified database that facilitates the understanding and usage of integron information. Integrall is built on PHP5 using MySQL 5.0.
== See also ==
* Antimicrobial resistance databases
== References == {{reflist}}
Category:Antimicrobial resistance organizations Category:Biological databases
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