Hokovirus

{{short description|Hypothesized genus of giant double-stranded DNA-containing viruses}} {{Distinguish|text=''Hokovirus'', shorthand for ''Hong Kong Virus'', former name of some viruses and virus species of genus ''Tetraparvovirus''}} {{Virusbox | taxon = Hokovirus }}

'''''Hokovirus''''' ('''HokV''') is a genus of giant double-stranded DNA-containing viruses (NCLDV). This genus was detected during the analysis of metagenome samples of bottom sediments of reservoirs at the wastewater treatment plant in Klosterneuburg, Austria. New ''Klosneuvirus'' (KNV), ''Catovirus'' and ''Indivirus'' genera (all found in these sewage waters) were also described together with ''Hokovirus'', building up a putative virus subfamily ''Klosneuvirinae'' (Klosneuviruses) with KNV as type genus.<ref name="Schulz2017">{{Cite journal |last1=Schulz |first1=Frederik |last2=Yutin |first2=Natalya |last3=Ivanova |first3=Natalia N. |last4=Ortega |first4=Davi R. |last5=Lee |first5=Tae Kwon |last6=Vierheilig |first6=Julia |last7=Daims |first7=Holger |last8=Horn |first8=Matthias |last9=Wagner |first9=Michael |date=2017-04-07 |title=Giant viruses with an expanded complement of translation system components|journal=Science |language=en |volume=356 |issue=6333 |pages=82–85 |doi=10.1126/science.aal4657 |pmid=28386012 |issn=0036-8075 |bibcode=2017Sci...356...82S |doi-access=free |url=https://escholarship.org/content/qt0kf9t6gn/qt0kf9t6gn.pdf }}</ref> ''Hokovirus'' has a large genome of 1.33 million base pairs (881 gene families). This is the third largest genome among known Klosneuviruses after KNV (1.57 million base pairs, 1272 gene families) and ''Catovirus''. GC content is 21.4 %<ref name="Schulz2017" /> Classification of metagenome, made by analyzing 18S rRNA indicate that their hosts are relate to the simple Cercozoa.<ref name="Schulz2017" />

Phylogenetic tree topology of ''Mimiviridae'' is still under discussion. Some authors (CNS 2018) like to put Klosneuviruses together with ''Cafeteria roenbergensis virus'' (CroV) and ''Bodo saltans virus'' (BsV) into a tentative subfamily called ''Aquavirinae''.<ref>Centre national de la recherche scientifique (CNS): [http://www.igs.cnrs-mrs.fr/wp-content/uploads/2018/05/TableVirus18_04_18.pdf List of the main “giant” viruses known as of today] {{Webarchive|url=https://web.archive.org/web/20190111233355/http://www.igs.cnrs-mrs.fr/wp-content/uploads/2018/05/TableVirus18_04_18.pdf |date=2019-01-11 }}, Université Aix Marseille, 18. April 2018</ref> Another proposal is to put them together with Mimiviruses into a subfamily ''Megavirinae''.<ref name="Deeg2018">{{cite journal |last1=Deeg |first1=C.M. |last2=Chow |first2=E.C.T. |last3=Suttle |first3=C.A. |title=The kinetoplastid-infecting Bodo saltans virus (BsV), a window into the most abundant giant viruses in the sea |journal=eLife |volume=7 |article-number=e33014 |year=2018 |doi=10.7554/eLife.33014 |pmid=29582753 |pmc=5871332 |doi-access=free }}</ref>

==References== {{Reflist}}

== Further reading == * Mitch Leslie: Giant viruses found in Austrian sewage fuel debate over potential fourth domain of life. In: Science. 5. April 2017, doi:10.1126/science.aal1005.

Category:Virus genera Category:Mimiviridae Category:Unaccepted virus taxa