Heyneanine

{{Chembox | ImageFile = Heyneanine.svg | ImageAlt = | IUPACName = (1''S'')-1-[(1''R'',15''R'',17''R'',18''R'')-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4,6,8-tetraen-17-yl]ethanol | OtherNames = |Section1={{Chembox Identifiers | CASNo = 4865-78-5 | CASNo_Ref = {{Cascite|changed|CAS}} | ChEMBL = 461609 | PubChem = 44566758 | ChemSpiderID = 10207461 | InChI=1S/C19H24N2O/c1-11(22)15-8-12-9-16-18-14(6-7-21(10-12)19(15)16)13-4-2-3-5-17(13)20-18/h2-5,11-12,15-16,19-20,22H,6-10H2,1H3/t11-,12-,15-,16-,19-/m0/s1 | InChIKey= TVPHSOXWTLOHCG-CCISYGEFSA-N | SMILES = C[C@@H]([C@@H]1C[C@H]2C[C@@H]3[C@H]1N(C2)CCC4=C3NC5=CC=CC=C45)O}} |Section2={{Chembox Properties | C=21 | H=26 | N=2 | O=3 | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = }} |Section3={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }} }}

'''Heyneanine''' is a ''Tabernaemontana'' alkaloid with ''in vitro'' antitumor activity.<ref>{{cite journal|pmid=23569415|year=2013|last1=Rizo|first1=WF|last2=Ferreira|first2=LE|last3=Colnaghi|first3=V|last4=Martins|first4=JS|last5=Franchi|first5=LP|last6=Takahashi|first6=CS|last7=Beleboni|first7=RO|last8=Marins|first8=M|last9=Pereira|first9=PS|last10=Fachin|first10=AL|title=Cytotoxicity and genotoxicity of coronaridine from Tabernaemontana catharinensis A.DC in a human laryngeal epithelial carcinoma cell line (Hep-2)|volume=36|issue=1|pages=105–10|doi=10.1590/S1415-47572013005000010|pmc=3615513|journal=Genetics and Molecular Biology}}</ref> It also inhibits butrylcholinesterase.<ref>{{cite web |url=https://www.scielo.br/pdf/aabc/v80n3/a03v80n3.pdf |title=Annals of the Brazilian Academy of Sciences|last= |first= |date= |website= |publisher= |access-date= |quote=}}</ref>

==See also== * Coronaridine * Voacangine

==References== {{reflist}}

Category:Indole alkaloids Category:Heterocyclic compounds with 5 rings Category:Methyl esters

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