{{Short description|Human leukocyte antigen serotype}} {| id="drugInfoBox" style="float: right; clear: right; margin: 0 0 0.5em 1em; background: #ffffff;" class="toccolours" border=0 cellpadding=0 align=right width="240px" |- | align="center" colspan="3" | |- style="text-align: center; line-height: 1.00;background:#eeeeee" | colspan="3" color="white" | |- | align="center" colspan="2" | |- | align="center" colspan="2" | <div style="font-size:medium; line-height:120%;">major histocompatibility complex (human), class I, B13</div> |- | bgcolor="#e7dcc3" | Alleles | bgcolor="#eeeeee" | B*1301, *1302<br> |- | colspan="2" bgcolor="#dddddd" | '''Structure''' (See HLA-B) |- | bgcolor="#e7dcc3" | Symbol(s) | bgcolor="#eeeeee" | [https://web.archive.org/web/20070821210135/http://www.gene.ucl.ac.uk/nomenclature/data/get_data.php?hgnc_id=4932 HLA-B] |- | bgcolor="#e7dcc3" | EBI-HLA | bgcolor="#eeeeee" | [http://www.ebi.ac.uk/cgi-bin/imgt/hla/get_allele.cgi?B*1301 B*1301] |- | bgcolor="#e7dcc3" | EBI-HLA | bgcolor="#eeeeee" | [http://www.ebi.ac.uk/cgi-bin/imgt/hla/get_allele.cgi?B*1302 B*1302] |- | bgcolor="#e7dcc3" | Locus | bgcolor="#eeeeee" | chr.6 ''[https://www.ncbi.nlm.nih.gov/Omim/getmap.cgi?chromosome=6p21.31 6p21.31]'' |- |}
'''HLA-B13''' (B13) is an HLA-B serotype. The serotype identifies the more common HLA-B*13 gene products.<ref name="pmid15787720">{{cite journal |pmc=2848993 |year=2010 |last1=Marsh |first1=S. G. |title=Nomenclature for factors of the HLA system, 2010 |journal=Tissue Antigens |volume=75 |issue=4 |pages=291–455 |last2=Albert |first2=E. D. |last3=Bodmer |first3=W. F. |last4=Bontrop |first4=R. E. |last5=Dupont |first5=B. |last6=Erlich |first6=H. A. |last7=Fernández-Viña |first7=M. |last8=Geraghty |first8=D. E. |last9=Holdsworth |first9=R. |last10=Hurley |first10=C. K. |last11=Lau |first11=M. |last12=Lee |first12=K. W. |last13=Mach |first13=B. |last14=Maiers |first14=M. |last15=Mayr |first15=W. R. |last16=Müller |first16=C. R. |last17=Parham |first17=P. |last18=Petersdorf |first18=E. W. |last19=Sasazuki |first19=T. |last20=Strominger |first20=J. L. |last21=Svejgaard |first21=A. |last22=Terasaki |first22=P. I. |last23=Tiercy |first23=J. M. |last24=Trowsdale |first24=J. |pmid=20356336 |doi=10.1111/j.1399-0039.2010.01466.x }}</ref> (For terminology help see: HLA-serotype tutorial)
==Serotype== {| border="0" cellspacing="0" cellpadding="0" align="center" style="text-align:center; background:#ffffff; margin-right: 1em; border:2px #e0e0ff solid;" |+ B13 serotype recognition of Some HLA B*13 allele-group gene products<ref>[http://www.ebi.ac.uk/imgt/hla/allele.html derived from IMGT/HLA]</ref> |- style="background:#f0f0ff" | style="width:60px" | B*13 || style="width:60px" | '''B13''' | style="width:60px" | || style="width:60px" | Sample |- style="background:#f0f0ff" | allele || % || % || size (N) |- | style = "background:#e8e8f8" | 1301 || 97 || || 238 |- | style = "background:#e8e8f8" | 1302 || 99 || || 1307 |}
==Allele frequencies== {|border="0" cellspacing="0" cellpadding="1" align="left" style="text-align:center; margin-right: 3em; border:1px #ffeebb solid; background:#f8f6f8; " |+ '''HLA B*1301 frequencies''' |- style="background:#efe5ef" | || || freq |- style="background:#eee5ef" | ref. || align="left" |Population || style="width:50px" | (%) |- | <ref name = "pmid12753660">{{cite journal |vauthors=Middleton D, Menchaca L, Rood H, Komerofsky R | title = New allele frequency database|url= http://www.allelefrequencies.net | journal = Tissue Antigens | volume = 61 | issue = 5 | pages = 403–7 | year = 2003 | pmid = 12753660 | doi =10.1034/j.1399-0039.2003.00062.x | doi-access = free }}</ref> || align="left"|Papua New Guinea Wosera||28.3 |- | || align="left"|Australian Aborigine Cape York Peninsula||27.0 |- | || align="left"|Taiwan Bunun||26.7 |- | || align="left"|Australian Aborigine Groote Eylandt||23.3 |- | || align="left"|Taiwan Thao||21.7 |- | || align="left"|Taiwan Tsou||17.6 |- | || align="left"|India Khandesh Pawra||12.0 |- | || align="left"|China South Han||8.2 |- | || align="left"|New Caledonia||7.7 |- | || align="left"|South Africa Natal Tamil||6.1 |- | || align="left"|Philippines Ivatan||6.0 |- | || align="left"|Papua New Guinea Eastern Highlands Goroka||5.7 |- | || align="left"|Singapore Riau Malay||5.4 |- | || align="left"|China North Han||4.8 |- | || align="left"|Thailand||4.1 |- | || align="left"|India West Coast Parsis||3.0 |- | || align="left"|India North Hindus||2.9 |- | || align="left"|Jordan Amman||2.1 |- | || align="left"|South Korea (3)||2.1 |- | || align="left"|Thailand||2.1 |- | || align="left"|China Inner Mongolia||2.0 |- | || align="left"|France South East||1.9 |- | || align="left"|Georgia Tbilisi Kurds||1.7 |- | || align="left"|Japan Central||1.5 |- | || align="left"|India Andhra Pradesh Golla||1.4 |- | || align="left"|India North Delhi||1.1 |-style="background:#fefefe" | <ref name = "pmid12753660"/> || |B*1302|| |- | || align="left"|India West Coast Parsis||16.0 |- | || align="left"|Cameroon Bakola Pygmy||7.0 |- | || align="left"|Czech Republic||6.6 |- | || align="left"|Georgia Svaneti Svans||6.3 |- | || align="left"|Georgia Tbilisi Georgians||5.6 |- | || align="left"|India Mumbai Marathas||4.3 |- | || align="left"|Romanian||4.1 |- | || align="left"|India West Bhils||4.0 |- | || align="left"|China North Han||3.8 |- | || align="left"|Sudanese||3.8 |- | || align="left"|South Korea pop 3||3.5 |- | || align="left"|Georgia Tbilisi Kurds||3.4 |- | || align="left"|Russia Tuva pop 2||3.3 |- | || align="left"|Israel Arab Druse||3.0 |- | || align="left"|Central Africa Republic Mbenzele Pygmy||2.8 |- | || align="left"|Israel Ashkenazi and Non Ashkenazi Jews||2.8 |- | || align="left"|Uganda Kampala||2.8 |- | || align="left"|Bulgaria||2.7 |- | || align="left"|Cameroon Yaounde||2.7 |- | || align="left"|Guinea Bissau||2.3 |- | || align="left"|Kenya Nandi||2.3 |- | || align="left"|India North Delhi||2.2 |- | || align="left"|Zimbabwe Harare Shona||2.2 |- | || align="left"|Kenya ||2.1 |- | || align="left"|Croatia||2.0 |- | || align="left"|Cameroon Bamileke||1.9 |- | || align="left"|USA North American Natives||1.9 |- | || align="left"|China South Han||1.8 |- | || align="left"|Finland||1.7 |- | || align="left"|Belgium||1.5 |- | || align="left"|South African Natal Zulu||1.5 |- | || align="left"|Tunisia||1.5 |- | || align="left"|India Andhra Pradesh Golla||1.4 |- | || align="left"|Azores Santa Maria and Sao Miguel||1.3 |- | || align="left"|Ireland South||1.2 |- | || align="left"|Singapore Chinese Han||1.2 |- | || align="left"|Kenya Luo||1.1 |- | || align="left"|Mexico Chihuahua State Tarahumara||1.1 |- | || align="left"|Tunisia Tunis||1.1 |- | || align="left"|Zambia Lusaka||1.1 |- | || align="left"|Portugal Centre||1.0 |- | || align="left"|Saudi Arabia Guraiat and Hail||1.0 |- | || align="left"|Singapore Javanese Indonesians||1.0 |} {{clear left}}
==References== {{reflist}}
{{HLA-B serotypes}}
{{DEFAULTSORT:Hla-B13}} 1