HDHD1A

{{Short description|Protein-coding gene in the species Homo sapiens}} {{cs1 config|name-list-style=vanc|display-authors=6}} {{Infobox_gene}} '''Haloacid dehalogenase-like hydrolase domain-containing protein 1A''' is an enzyme that in humans is encoded by the ''HDHD1A'' gene.<ref name="pmid1734713">{{cite journal | vauthors = Salido EC, Yen PH, Koprivnikar K, Yu LC, Shapiro LJ | title = The human enamel protein gene amelogenin is expressed from both the X and the Y chromosomes | journal = American Journal of Human Genetics | volume = 50 | issue = 2 | pages = 303–16 | date = February 1992 | pmid = 1734713 | pmc = 1682460 }}</ref><ref name="pmid1284467">{{cite journal | vauthors = Yen PH, Ellison J, Salido EC, Mohandas T, Shapiro L | title = Isolation of a new gene from the distal short arm of the human X chromosome that escapes X-inactivation | journal = Human Molecular Genetics | volume = 1 | issue = 1 | pages = 47–52 | date = April 1992 | pmid = 1284467 | doi = 10.1093/hmg/1.1.47 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: HDHD1A haloacid dehalogenase-like hydrolase domain containing 1A| url = https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=8226}}</ref> It encodes a pseudouridine-5'-phosphatase but can also accommodate other phopshorylated metabolites with a lower affinity.<ref>{{cite journal | vauthors = Preumont A, Rzem R, Vertommen D, Van Schaftingen E | title = HDHD1, which is often deleted in X-linked ichthyosis, encodes a pseudouridine-5'-phosphatase | journal = The Biochemical Journal | volume = 431 | issue = 2 | pages = 237–44 | date = October 2010 | pmid = 20722631 | doi = 10.1042/bj20100174 | url = https://hal.science/hal-00521555/file/PEER_stage2_10.1042%252FBJ20100174.pdf }}</ref><ref>{{cite journal | vauthors = Defenouillère Q, Verraes A, Laussel C, Friedrich A, Schacherer J, Léon S | title = The induction of HAD-like phosphatases by multiple signaling pathways confers resistance to the metabolic inhibitor 2-deoxyglucose | journal = Science Signaling | volume = 12 | issue = 597 | article-number = eaaw8000 | date = September 2019 | pmid = 31481524 | doi = 10.1126/scisignal.aaw8000 | s2cid = 201829818 | url = https://hal.archives-ouvertes.fr/hal-03064377/file/Defenouillere%20HAL.pdf }}</ref>

== References == {{reflist}}

== Further reading == {{refbegin | 2}} * {{cite journal | vauthors = Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S | title = Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes | journal = Genome Research | volume = 16 | issue = 1 | pages = 55–65 | date = January 2006 | pmid = 16344560 | pmc = 1356129 | doi = 10.1101/gr.4039406 }} * {{cite journal | vauthors = Suzuki Y, Tsunoda T, Sese J, Taira H, Mizushima-Sugano J, Hata H, Ota T, Isogai T, Tanaka T, Nakamura Y, Suyama A, Sakaki Y, Morishita S, Okubo K, Sugano S | title = Identification and characterization of the potential promoter regions of 1031 kinds of human genes | journal = Genome Research | volume = 11 | issue = 5 | pages = 677–84 | date = May 2001 | pmid = 11337467 | pmc = 311086 | doi = 10.1101/gr.gr-1640r }} * {{cite journal | vauthors = Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S | title = Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library | journal = Gene | volume = 200 | issue = 1–2 | pages = 149–56 | date = October 1997 | pmid = 9373149 | doi = 10.1016/S0378-1119(97)00411-3 }} * {{cite journal | vauthors = Maruyama K, Sugano S | title = Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides | journal = Gene | volume = 138 | issue = 1–2 | pages = 171–4 | date = January 1994 | pmid = 8125298 | doi = 10.1016/0378-1119(94)90802-8 }} {{refend}}