Growing teeth

{{Short description|Bioengineering technology to create teeth}} {{Use dmy dates|date=December 2023}} '''Growing teeth''' is a bioengineering technology with the ultimate goal to create new full molars in a person or an animal.

== Chronology == * 2002 – British scientists have learned how to grow almost whole, but feeble teeth from single cells. * 2007 – Japanese scientists have bred mice almost full new teeth, but without a root. * 2009 – from the stem cells were grown full teeth in mice, and even managed to grow a tooth root, previously it was not possible, but there is a problem, it is that grown teeth were slightly less "native" teeth.<ref name=autogenerated1>{{cite news |last1=Normile |first1=Dennis |title=Researchers Grow New Teeth in Mice |work=Science |date=3 August 2009 |url=https://www.science.org/content/article/researchers-grow-new-teeth-mice }}</ref> * 2013 - Chinese scientists grow human teeth in mice using stem cells taken from human urine.<ref>{{Cite web | url=http://www.nhs.uk/news/2013/07july/pages/stem-cells-extracted-from-urine-used-to-grow-teeth.aspx | title=Stem cells extracted from urine used to 'grow teeth' - NHS | access-date=23 March 2014 | archive-date=9 March 2017 | archive-url=https://web.archive.org/web/20170309111202/http://www.nhs.uk/news/2013/07July/Pages/Stem-cells-extracted-from-urine-used-to-grow-teeth.aspx/ | url-status=dead }}</ref> * 2015 - Growing New Teeth in the Mouth Using Stem-Cell Dental Implants <ref>{{Cite web | url=https://www.prescouter.com/2015/07/growing-new-teeth-in-the-mouth-using-stem-cell-dental-implants/ |title = Growing New Teeth in the Mouth Using Stem-Cell Dental Implants |work=PreScouter |date = 26 July 2015}}</ref> * 2018 - Protein disorder–order interplay to guide the growth of hierarchical mineralized structures.<ref>{{cite journal |last1=Elsharkawy |first1=Sherif |last2=Al-Jawad |first2=Maisoon |last3=Pantano |first3=Maria F. |last4=Tejeda-Montes |first4=Esther |last5=Mehta |first5=Khushbu |last6=Jamal |first6=Hasan |last7=Agarwal |first7=Shweta |last8=Shuturminska |first8=Kseniya |last9=Rice |first9=Alistair |last10=Tarakina |first10=Nadezda V. |last11=Wilson |first11=Rory M. |last12=Bushby |first12=Andy J. |last13=Alonso |first13=Matilde |last14=Rodriguez-Cabello |first14=Jose C. |last15=Barbieri |first15=Ettore |last16=del Río Hernández |first16=Armando |last17=Stevens |first17=Molly M. |last18=Pugno |first18=Nicola M. |last19=Anderson |first19=Paul |last20=Mata |first20=Alvaro |title=Protein disorder–order interplay to guide the growth of hierarchical mineralized structures |journal=Nature Communications |date=1 June 2018 |volume=9 |issue=1 |pages=2145 |doi=10.1038/s41467-018-04319-0 |pmid=29858566 |pmc=5984621 |bibcode=2018NatCo...9.2145E }}</ref>

== Methods == * '''Outer''' – the tooth is grown separately and implanted in the patient. * '''Inner''' – the tooth is grown directly into the patient's mouth.

== Regenerative Research == * 2012 – Indian researchers found a way to cure and regenerate an infected root canal through stem cell activation. This replaces the old method of removing the tooth nerve.<ref>{{Cite news | url=http://www.thehindu.com/sci-tech/health/breakthrough-dentistry/article5076022.ece | title=Breakthrough dentistry| newspaper=The Hindu| date=September 2013| last1=Dutt| first1=Anuradha}}</ref> * 2013 - Swiss researchers regenerate tooth enamel of early cavities using a peptide-based biomaterial.<ref>{{cite journal |last1=Brunton |first1=P. A. |last2=Davies |first2=R. P. W. |last3=Burke |first3=J. L. |last4=Smith |first4=A. |last5=Aggeli |first5=A. |last6=Brookes |first6=S. J. |last7=Kirkham |first7=J. |title=Treatment of early caries lesions using biomimetic self-assembling peptides – a clinical safety trial |journal=British Dental Journal |date=August 2013 |volume=215 |issue=4 |pages=E6 |doi=10.1038/sj.bdj.2013.741 |pmid=23969679 |pmc=3813405 }}</ref>

==References== {{Reflist}}

== Links == * [http://news.discovery.com/animals/alligators-inspire-new-way-for-people-to-regrow-teeth-130513.htm Alligators Inspire New Way for Growing Teeth] {{Webarchive|url=https://web.archive.org/web/20160313004430/http://news.discovery.com/animals/alligators-inspire-new-way-for-people-to-regrow-teeth-130513.htm |date=13 March 2016 }}

Growing teeth Category:Human anatomy Category:Biological engineering