Mannose-1-phosphate guanyltransferase beta is an enzyme that in humans is encoded by the GMPPB gene.[1]
This gene is thought to encode a GDP-mannose pyrophosphorylase. This enzyme catalyzes the reaction which converts mannose-1-phosphate and GTP to GDP-mannose which is involved in the production of N-linked oligosaccharides. The gene encodes two transcript variants.[1]
References
Further reading
- Rual JF, Venkatesan K, Hao T (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026
- Gerhard DS, Wagner L, Feingold EA (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res.. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334
- Ota T, Suzuki Y, Nishikawa T (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet.. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039
- Clark HF, Gurney AL, Abaya E (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res.. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309
- Ono T, Sekino-Suzuki N, Kikkawa Y (2003). "Alivin 1, a novel neuronal activity-dependent gene, inhibits apoptosis and promotes survival of cerebellar granule neurons.". J. Neurosci.. 23 (13): 5887–96. doi:10.1523/JNEUROSCI.23-13-05887.2003. PMC 6741272. PMID 12843293
- Strausberg RL, Feingold EA, Grouse LH (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A.. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932
- Nagase T, Nakayama M, Nakajima D (2001). "Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res.. 8 (2): 85–95. doi:10.1093/dnares/8.2.85. PMID 11347906
- Ning B, Elbein AD (2001). "Cloning, expression and characterization of the pig liver GDP-mannose pyrophosphorylase. Evidence that GDP-mannose and GDP-Glc pyrophosphorylases are different proteins.". Eur. J. Biochem.. 267 (23): 6866–74. doi:10.1046/j.1432-1033.2000.01781.x. PMID 11082198