| Iupac name | 2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethylurea |
|---|---|
| Legal status | Uncontrolled |
| Routes of administration | Oral |
| Cas number | 76716-60-4 |
| Atc prefix | none |
| Pubchem | 71153 |
| Drugbank | DB20166 |
| Chembl | 2106753 |
| Chemspiderid | 64297 |
| Unii | 713BBL6840 |
| Synonyms | DU-27,716; DU-27716; DU27716 |
| C | 14 |
| H | 19 |
| F | 3 |
| N | 4 |
| O | 1 |
| Smiles | C1CN(CCN1CCNC(=O)N)C2=CC=CC(=C2)C(F)(F)F |
Fluprazine (developmental code name DU-27,716) is a drug of the phenylpiperazine family.[1] It is a so-called serenic or antiaggressive agent.[2] It is closely related to several other piperazines, including eltoprazine and batoprazine, and TFMPP, as well as more distantly to the azapirones such as buspirone. The pharmacology of fluprazine is unknown, but it is likely to act as an agonist at the 5-HT1A and 5-HT1B receptors like its sister compound eltoprazine.[1]
See also
References
- ^ "Delving into the Latest Updates on Fluprazine with Synapse". Synapse. 8 May 2025. Retrieved 19 January 2026.
- ^ van der Poel AM, Olivier B, Mos J, Kruk MR, Meelis W, van Aken JH (1982). "Anti-aggressive effect of a new phenylpiperazine compound (DU27716) on hypothalamically induced behavioural activities.". Pharmacol Biochem Behav. 17 (1): 147–153. doi:10.1016/0091-3057(82)90277-5. PMID 6889746. S2CID 34142798