{{Short description|British physician}} {{Use dmy dates|date=April 2022}} {{Third-party|date=September 2021}} {{Infobox scientist | name = Eleanor Barnes | workplaces = John Radcliffe Hospital <br /> University of Oxford | alma_mater = University of Oxford <br /> St Bartholomew's Hospital | thesis_title = T-cell and dendritic cell function and the effects of combination therapy in Hepatitis C virus infection | thesis_url = http://www.worldcat.org/oclc/1169825441 | thesis_year = 2004 }} '''Eleanor Barnes''' is a British physician at the John Radcliffe Hospital and a Professor of Hepatology and Experimental Medicine at the University of Oxford. She has studied hepatitis C and the development of the development of HCV vaccines. She is a Fellow of the Academy of Medical Sciences and serves as the lead for hepatology at the National Institute for Health Research (NIHR) Clinical Research Network.<ref>{{Cite web|title=Ellie (Eleanor) Barnes|url=https://www.ndm.ox.ac.uk/team/ellie-eleanor-barnes|url-status=live|access-date=2021-12-22|website=Nuffield Department of Medicine, University of Oxford|language=en|archive-url=https://web.archive.org/web/20200922122854/https://www.ndm.ox.ac.uk/team/ellie-eleanor-barnes |archive-date=2020-09-22 }}</ref>
== Early life and education == Barnes has said that she was interested in science as a child.<ref name=":0">{{Cite web|title=Eleanor Barnes — Diversity Projects|url=https://parking.haiku.fry-it.com/wis/meet/37|access-date=2021-09-18|website=parking.haiku.fry-it.com}}</ref> She decided to study medicine at university, and eventually trained at St Bartholomew's Hospital.<ref name=":0" /> She completed an intercalated bachelor's degree in anthropology and philosophy.<ref name=":0" /> After graduating, she worked as a medical resident at the Royal Free Hospital, where she decided to specialise in hepatology and gastroenterology. Determined to pursue a career in research, Barnes worked unpaid for three months, during which time she obtained data that she used to apply for a fellowship from the Medical Research Council.<ref>{{Cite web |title=Eleanor Barnes — Diversity Projects |url=https://parking.haiku.fry-it.com/wis/meet/37 |access-date=2022-03-01 |website=parking.haiku.fry-it.com}}</ref> She was a doctoral researcher at the University of Oxford. Her doctoral research considered T cell and dendritic cell function.<ref>{{Cite thesis|title=T-cell and dendritic cell function and the effects of combination therapy in Hepatitis C virus infection|date=2004|language=English|first=Eleanor|last=Barnes|oclc=1169825441 }}</ref>
== Research and career == Barners' research considers T cell immunology. She is focused on the translation of laboratory findings to clinical environments. Barnes worked as a Medical Research Council Senior Fellow at the University of Oxford, and eventually was appointed lead of herpetology in the Thames Valley.<ref name=":1">{{Cite web|title=Ellie Barnes: Women in Science - Internal Speaker — Working for NDM|url=https://www.ndm.ox.ac.uk/working-for-ndm/working-for-ndm/be-inspired/women-in-science-podcasts/ellie-barnes-women-in-science-internal-speaker|access-date=2021-09-18|website=www.ndm.ox.ac.uk}}</ref><ref>{{Cite web|title=PITCH Study|url=https://www.pitch-study.org/team.html|access-date=2021-09-18|website=www.pitch-study.org}}</ref> She studied why 80% of patients with hepatitis C get chronic infection.<ref name=":1" /> Barnes identified that the nature of the T cell response determines which pathway a patient goes down. This observation led Barnes to develop an T-cell vaccine to prevent hepatitis C infection. The vaccine is based on adenoviral vectors, which host the non-structural proteins of hepatitis C from a genotype 1B strain.<ref name=":1" /> There are seven major hepatitis C strains, which presents considerable challenges for the development of vaccines.<ref name=":1" /> Barnes was elected Fellow of the Academy of Medical Sciences in 2018.<ref>{{Cite web|title=Professor Eleanor Barnes {{!}} The Academy of Medical Sciences|url=https://acmedsci.ac.uk/fellows/fellows-directory/ordinary-fellows/fellow/Professor-Eleanor-Barnes-0021056|access-date=2021-09-18|website=acmedsci.ac.uk}}</ref>
During the COVID-19 pandemic, Barnes studied the design, effectiveness and implementation of the COVID-19 vaccine.<ref>{{Cite web|date=2021-07-22|title=UK scientists back Covid boosters as study finds post-jab falls in antibodies|url=http://www.theguardian.com/world/2021/jul/22/uk-scientists-back-covid-boosters-as-study-finds-post-jab-falls-in-antibodies|access-date=2021-09-18|website=the Guardian|language=en}}</ref> She showed that patients who suffered from COVID-19 were likely to be impacted by liver problems.<ref>{{Cite web|date=2021-07-23|title=Liver problems common among COVID-19 patients, study finds|url=https://oxfordbrc.nihr.ac.uk/liver-problems-common-among-covid-19-patients-study-finds/|access-date=2021-09-18|website=NIHR Oxford Biomedical Research Centre|language=en-US}}</ref>
== Selected publications == * {{Cite Q|Q34431175}} * {{Cite Q|Q104286457}} * {{Cite Q|Q97678476}}
== Personal life == Barnes is married with two children.<ref name=":1" />
== References == {{reflist}}
{{Authority control}}
{{DEFAULTSORT:Barnes, Eleanor}} Category:Fellows of the Academy of Medical Sciences (United Kingdom) Category:British women scientists Category:British women academics Category:Academics of the University of Oxford Category:20th-century British medical doctors Category:20th-century British women medical doctors Category:21st-century British medical doctors Category:NIHR Senior Investigators Category:Hepatitis researchers Category:Year of birth missing (living people) Category:Living people Category:Alumni of the University of Oxford