Duncan Odom

{{Short description|American research group leader}} {{Infobox scientist | name = Duncan T. Odom | birth_name = Duncan Odom | image =  | image_size = | image_upright = | alt = | caption = | birth_date =  | birth_place = | other_names = | residence = | citizenship = | nationality = | fields = {{Plainlist| * Evolution * Genomics * Bioinformatics * Transition metal chemistry * Gene expression<ref name=googlescholar/>}} | workplaces = {{Plainlist| * DKFZ German Cancer Research Center * Heidelberg University * University of Cambridge * Cancer Research UK * Wellcome Trust Sanger Institute<ref name=sanger>{{cite web|archive-url=https://web.archive.org/web/20160907141336/http://www.sanger.ac.uk/people/directory/odom-duncan|archive-date=2016-09-07|url=http://www.sanger.ac.uk/people/directory/odom-duncan|website=sanger.ac.uk|author=Anon|year=2016|title=Dr Duncan Odom: Associate Faculty|publisher=Wellcome Trust|url-status=dead}}</ref> * Whitehead Institute}} | patrons = | education = | alma_mater = {{Plainlist| * New College of Florida (BA) * California Institute of Technology (PhD)}} | thesis_title = The application of metallointercalators in recognition of and charge transport in nucleic acids | thesis_url = https://doi.org/10.7907%2Fyz1f-w961 | thesis_year = 2001 | doctoral_advisor = Jacqueline Barton<ref name=phd/> | academic_advisors = Richard A. Young<ref name=orcid/> | doctoral_students = Christina Ernst<ref name=cphd/> | notable_students = | known_for = | influences = | influenced = | awards = {{Plainlist| * Crick Lecture (2014)<ref name=crick/> * EMBO Member (2015)<ref name=membo>{{cite web|author=Anon|year=2015|url=http://people.embo.org/profile/duncan-t-odom|website=people.embo.org|title=Duncan T. Odom|publisher=European Molecular Biology Organization|location=Heidelberg}}</ref>}} Mary Lyon Award (2016) | spouse =  | partner =  | children = | signature =  | signature_alt = | website = {{Official URL}} | footnotes = }} '''Duncan T. Odom''' is a research division head at the German Cancer Research Center (DKFZ) in Heidelberg, and a University Professor at Heidelberg University. Previously he was a research group leader at the Cancer Research UK Cambridge Institute (CRUK CI) at the University of Cambridge (2006-2022)<ref name=googlescholar>{{Google scholar id}}</ref><ref name=epmc>{{EuropePMC}}</ref><ref name=orcid/> and an associate faculty member at the Wellcome Trust Sanger Institute (2011-2018).<ref name=sanger/>

==Education== Odom was educated at the New College of Florida where he was awarded a Bachelor of Arts degree in Chemistry in 1995.<ref name=sanger/> He continued his study at California Institute of Technology (Caltech) where he was awarded a PhD in chemistry for research on DNA-binding metallo-intercalators supervised by Jacqueline Barton.<ref name=orcid>Duncan Odom {{ORCID|0000-0001-6201-5599}}</ref><ref name=phd>{{cite thesis |degree=PhD |first=Duncan T.|last=Odom |title=The application of metallointercalators in recognition of and charge transport in nucleic acids |publisher=California Institute of Technology |date=2001|doi=10.7907/yz1f-w961 |oclc=874759941 |id={{ProQuest|251012080}}|url=http://resolver.caltech.edu/CaltechTHESIS:03212014-095851500|website=caltech.edu}}</ref>

==Career and research== After a period as a postdoctoral researcher<ref name=postdoc>{{Cite journal | pmid = 25001498| pmc = 4053951| year = 2014| last1 = Odom| first1 = Duncan T.|authorlink1=Duncan Odom| title = Survival strategies for choosing the right postdoc position| journal = Genome Biology| volume = 15| issue = 3| pages = 107| doi = 10.1186/gb4163 | doi-access = free}} {{open access}}</ref> in genetics and genomics at the Whitehead Institute in Cambridge, Massachusetts with Richard A. Young,<ref name=sanger/> he established his research group at the University of Cambridge in 2006.<ref name=orcid/> His research investigates how transcription and transcriptional regulation vary during evolution, and its implications for diseases such as cancer, using high throughput biology methods to investigate genome evolution.<ref name=cruk>{{cite web|archive-url=https://web.archive.org/web/20170207043900/http://www.cruk.cam.ac.uk/research-groups/odom-group|archive-date=2017-02-07|url=http://www.cruk.cam.ac.uk/research-groups/odom-group|website=cruk.cam.ac.uk|title=Odom group: Transcription Regulation Laboratory|first=Duncan|last=Odom|year=2017|url-status=dead}}</ref><ref name="VillarBerthelot2015">{{cite journal|last1=Villar|first1=Diego|last2=Berthelot|first2=Camille|last3=Aldridge|first3=Sarah|last4=Rayner|first4=Tim F.|last5=Lukk|first5=Margus|last6=Pignatelli|first6=Miguel|last7=Park|first7=Thomas J.|last8=Deaville|first8=Robert|last9=Erichsen|first9=Jonathan T.|last10=Jasinska|first10=Anna J.|last11=Turner|first11=James M.A.|last12=Bertelsen|first12=Mads F.|last13=Murchison|first13=Elizabeth P.|last14=Flicek|first14=Paul|last15=Odom|first15=Duncan T.|title=Enhancer Evolution across 20 Mammalian Species|journal=Cell|volume=160|issue=3|year=2015|pages=554–566|issn=0092-8674|doi=10.1016/j.cell.2015.01.006|pmid=25635462|pmc=4313353}}</ref><ref name="StefflovaThybert2013">{{cite journal|last1=Stefflova|first1=Klara|last2=Thybert|first2=David|last3=Wilson|first3=Michael D.|last4=Streeter|first4=Ian|last5=Aleksic|first5=Jelena|last6=Karagianni|first6=Panagiota|last7=Brazma|first7=Alvis|last8=Adams|first8=David J.|last9=Talianidis|first9=Iannis|last10=Marioni|first10=John C.|last11=Flicek|first11=Paul|last12=Odom|first12=Duncan T.|title=Cooperativity and Rapid Evolution of Cobound Transcription Factors in Closely Related Mammals|pmid= 23911320|pmc=3732390 |journal=Cell|volume=154|issue=3|year=2013|pages=530–540|issn=0092-8674|doi=10.1016/j.cell.2013.07.007}} {{open access}}</ref><ref name="ErnstPike2016">{{cite journal|last1=Ernst|first1=Christina|last2=Pike|first2=Jeremy|last3=Aitken|first3=Sarah J|last4=Long|first4=Hannah K|last5=Eling|first5=Nils|last6=Stojic|first6=Lovorka|last7=Ward|first7=Michelle C|last8=Connor|first8=Frances|last9=Rayner|first9=Timothy F|last10=Lukk|first10=Margus|last11=Klose|first11=Robert J|last12=Kutter|first12=Claudia|last13=Odom|first13=Duncan T|title=Successful transmission and transcriptional deployment of a human chromosome via mouse male meiosis|journal=eLife|volume=5|year=2016|issn=2050-084X|doi=10.7554/eLife.20235|pmid=27855777|pmc=5161449 |doi-access=free }} {{open access}}</ref> {{As of|2017}}, according to Google Scholar his most highly-cited papers have been published in ''Cell'',<ref name="LeeJenner2006">{{cite journal |last1=Lee |first1=Tong Ihn |last2=Jenner |first2=Richard G. |last3=Boyer |first3=Laurie A. |author-link3=Laurie Boyer |last4=Guenther |first4=Matthew G. |last5=Levine |first5=Stuart S. |last6=Kumar |first6=Roshan M. |last7=Chevalier |first7=Brett |last8=Johnstone |first8=Sarah E. |last9=Cole |first9=Megan F. |last10=Isono |first10=Kyo-ichi |last11=Koseki |first11=Haruhiko |year=2006 |title=Control of Developmental Regulators by Polycomb in Human Embryonic Stem Cells |journal=Cell |volume=125 |issue=2 |pages=301–313 |doi=10.1016/j.cell.2006.02.043 |issn=0092-8674 |pmc=3773330 |pmid=16630818 |last12=Fuchikami |first12=Takuya |last13=Abe |first13=Kuniya |last14=Murray |first14=Heather L. |last15=Zucker |first15=Jacob P. |last16=Yuan |first16=Bingbing |last17=Bell |first17=George W. |last18=Herbolsheimer |first18=Elizabeth |last19=Hannett |first19=Nancy M. |last20=Sun |first20=Kaiming |last21=Odom |first21=Duncan T. |last22=Otte |first22=Arie P. |last23=Volkert |first23=Thomas L. |last24=Bartel |first24=David P. |last25=Melton |first25=Douglas A. |last26=Gifford |first26=David K. |last27=Jaenisch |first27=Rudolf |last28=Young |first28=Richard A. |authorlink28=Richard A. Young}} {{open access}}</ref> ''Chemical Reviews'',<ref name="ErkkilaOdom1999">{{cite journal|last1=Erkkila|first1=Kathryn E.|last2=Odom|first2=Duncan T.|last3=Barton|first3=Jacqueline K.|title=Recognition and Reaction of Metallointercalators with DNA|journal=Chemical Reviews|volume=99|issue=9|year=1999|pages=2777–2796|issn=0009-2665|doi=10.1021/cr9804341|pmid=11749500}}</ref> and ''Science''.<ref name="Lee2002">{{cite journal|last1=Lee|first1=T. I.|title=Transcriptional Regulatory Networks in Saccharomyces cerevisiae|journal=Science|volume=298|issue=5594|year=2002|pages=799–804|issn=0036-8075|doi=10.1126/science.1075090|pmid= 12399584|bibcode=2002Sci...298..799L|s2cid=4841222}}</ref><ref name="Odom2004">{{cite journal|last1=Odom|first1=D. T.|title=Control of Pancreas and Liver Gene Expression by HNF Transcription Factors|journal=Science|volume=303|issue=5662|year=2004|pages=1378–1381|issn=0036-8075|doi=10.1126/science.1089769|pmid= 14988562|pmc=3012624|bibcode=2004Sci...303.1378O}} {{open access}}</ref>

His research has been funded by the National Institute of Diabetes and Digestive and Kidney Diseases,<ref name=orcid/> the Alfred P. Sloan Foundation, the European Research Council (ERC),{{citation needed|date=November 2018}} the European Molecular Biology Organization (EMBO), the Wellcome Trust<ref name=wellcome>{{cite web|title=Investigator Awards in Science: people we've funded|archive-url=https://web.archive.org/web/20170426142635/https://wellcome.ac.uk/what-we-do/directories/investigator-awards-science-people-funded|archive-date=2017-04-26|url=https://wellcome.ac.uk/what-we-do/directories/investigator-awards-science-people-funded|website=wellcome.ac.uk|author=Anon|year=2017|publisher=Wellcome Trust|url-status=dead}}</ref> and Cancer Research UK.<ref name=orcid/> His former doctoral students include Christina Ernst.<ref name=cphd>{{cite thesis|degree=PhD|publisher=University of Cambridge|url=https://www.repository.cam.ac.uk/handle/1810/278212|doi=10.17863/CAM.25556|title=Transcriptional and developmental consequences of aneuploidy during male meiosis|first= Christina|last=Ernst|date=2018|id={{EThOS|uk.bl.ethos.753466}}|website=cam.ac.uk|oclc=1065352558}} {{free access}}</ref>

===Awards and honours=== Odom was awarded the Crick Lecture by the Royal Society in 2014<ref name=crick>{{cite web|url=https://royalsociety.org/science-events-and-lectures/2014/francis-crick/|website=royalsociety.org|author=Anon|year=2014|publisher=Royal Society|title=Crick Lecture: Genetic control and the mammalian radiation|archive-url=https://web.archive.org/web/20170503164005/https://royalsociety.org/science-events-and-lectures/2014/francis-crick/|archive-date=2017-05-03|location=London|url-status=dead}}</ref><ref name=cricktube>{{YouTube|id=kPsf3793Rhc|title=Event video: Genetic control and the mammalian radiation}}</ref> for his "pioneering work in the field of comparative functional genomics, which has changed our understanding of the evolution of mammalian transcriptional regulation."<ref name=crick/> He was awarded EMBO Membership in 2015,<ref name=membo/> and the Mary F. Lyon Medal from The Genetics Society in 2016.<ref name="lyon">{{cite web|url=http://www.genetics.org.uk/medals-and-prizes/2015-winners/mary-lyon-medal/mary-lyon-medal-2016-dr-duncan-odum/|title=Mary Lyon Medal 2016 – Dr Duncan Odom|website=The Genetics Society|access-date=28 November 2018}}</ref>

==References== {{Reflist}}

{{DEFAULTSORT:Odom, Duncan}} Category:Year of birth missing (living people) Category:Living people Category:American bioinformaticians Category:Members of the European Molecular Biology Organization