{{Short description|Lacking habituation or tolerance to pharmacological agents}} {{refimprove|date=December 2009}} [[Image:Caffeinated spiderwebs.jpg|frame|right|An image comparing the web of a drug-naïve spider to that of a spider having been given caffeine.]]
'''Drug naïvety''' is the physiological state of non-habituation or non-tolerance to either a specific drug or broader set of drugs related by pharmacological criteria.<ref>{{Cite interview|url=http://www.medscape.org/viewarticle/510017|title=ART Advances for Drug-Naive Patients: An Expert Interview With Calvin J. Cohen, MD|first=Calvin J.|last=Cohen|work=Medscape|date=2005|access-date=2017-10-12}}</ref> The term applies to the administration of psychotropics in contexts ranging from the professional medical treatment of patients to the non-medical abuse of any drug, as well as the veterinarian. <!--Major re-write and expansion in process; please do not alter substantially--> <!--(including medical patients and non-medical drug users) or animals are those not habituated to a particular psychotropic substance (drugs). In the context of medical or scientific studies, subjects undergoing drug-related testing, such as the effect of a certain drug on behaviour or cognitive ability, are typically drug-naïve.-->
In addition to not being habituated, a drug-naïve person may have never received a particular drug. The same dose could be lethal for a drug-naïve person while having little effect on a heavily habituated person. In a medical context drug-naïveté is important considering medication dosage (pain medication, anxiety medication, anaesthesia, etc.), as the level of habituation affects a patient's baseline resistance to the effects of such medications.
==See also== *Scientific control
== Notes and references== {{Reflist}}
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{{DEFAULTSORT:Drug-Naive}} Category:Drugs
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