'''Domninus''' may refer to:

==Saints== *Saint Domninus or Saint Domnius, also Saint Duje, 3rd-century Syrian martyr-bishop, patron of the city of Split *Saint Domninus of Fidenza (San Donnino di Fidenza) (d. 304) *Saint Domninus of Parma (early 4th century), martyr under Diocletian *Saint Domninus of Thessalonica (early 4th century), martyr (October 1, Eastern Orthodox liturgics) *Saint Domninus of Digne, otherwise Saint Domnin (d. 379) *Saint Domninus of Grenoble (d. 386), first bishop of Grenoble *Saint Domninus of Vienne (d. 536), bishop of Vienne

==Others== *Domninus of Larissa, 5th-century Hellenistic Syrian Jewish mathematician *Domninus of Antioch (Domnus), patriarch of Antioch (see List of Patriarchs of Antioch) *Domnus II of Antioch *Roman figure in the time of Petronius Maximus *Man whom Serapion of Antioch addresses in one of his works

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