{{short description|American biologist}}{{Infobox scientist | name = Daniel Hartl | fields = Evolutionary Biology, Genetics | workplaces = University of Minnesota <br> Purdue University <br> Washington University in St. Louis <br> Harvard University | alma_mater = University of Wisconsin–Stevens Point at Wausau<br> University of Wisconsin–Madison }}
'''Daniel L. Hartl''' (born 1943) is the Higgins Professor of Biology in the Department of Organismic and Evolutionary Biology at Harvard University. He is also a principal investigator at the Hartl Laboratory at Harvard University. His research interests are focused on evolutionary genomics, molecular evolution, and population genetics.<ref name=":0">{{Cite web|url=http://hartlgroup.oeb.harvard.edu/people/daniel-hartl|title=Daniel Hartl|website=hartlgroup.oeb.harvard.edu|access-date=2017-01-03}}</ref>
== Early life == Hartl was born in 1943 and spent his childhood in Antigo, Wisconsin. He has three brothers and grew up with foster children living in his home. Hartl's father worked in a cheese factory and his mother worked nights as a sous chef.<ref name=":1">{{cite journal|last1=Tinsley|first1=H. D.|title=Profile of Daniel L. Hartl|journal=Proceedings of the National Academy of Sciences|date=22 May 2007|volume=104|issue=22|pages=9111–9113|doi=10.1073/pnas.0703562104|pmid=17519326|pmc=1896087|bibcode=2007PNAS..104.9111T |doi-access=free}}</ref>
== Education == Hartl was not exposed to the study of genetics in high school, and he was not sure he would go to college. His high school teacher, Robert Meyer, encouraged Hartl to apply for a scholarship, which allowed him to attend University of Wisconsin–Marathon County in Wausau, Wisconsin for two years.<ref name=":3" /> He had just enough money for tuition, and his brothers bought him a car so he could commute the 35 miles to school.<ref name=":1" /> He then transferred to the main campus of the University of Wisconsin–Madison. He remained at the University of Wisconsin, Madison to earn his PhD in genetics.<ref name=":0" /><ref name=":3" /> Hartl studied ''Drosophila'' (a group of fruit flies) and investigated "the mystery of segregation distortion."<ref name=":1" />
In 1968 he began postdoctoral work at the University of California in Berkeley, where he worked with geneticist Spencer Brown.<ref name=":3" />
== Academic career == Beginning in 1969 Hartl had faculty positions at the University of Minnesota College of Liberal Arts, Purdue University, Arts and Sciences at Washington University in St. Louis, and Harvard Faculty of Arts and Sciences.<ref name=":0" /> He has been at Harvard since 1993.<ref name=":3" /> Hartl is the Higgins Professor of Biology in the Department of Organismic and Evolutionary Biology at Harvard University.<ref name=":3" />
== Research == Hartl began his career studying genetics of segregation distortion in ''Drosophila''<ref name=":1" />''.'' He has published work on population genetic theory, tests of selection,<ref>{{Cite journal|last1=Sawyer|first1=S. A.|last2=Hartl|first2=D. L.|date=1992-12-01|title=Population genetics of polymorphism and divergence.|url=http://www.genetics.org/content/132/4/1161|journal=Genetics|language=en|volume=132|issue=4|pages=1161–1176|doi=10.1093/genetics/132.4.1161|issn=0016-6731|pmid=1459433|pmc=1205236}}</ref> evolution of antimicrobial resistance in ''E. coli''<ref>{{Cite journal|last1=Weinreich|first1=Daniel M.|last2=Delaney|first2=Nigel F.|last3=DePristo|first3=Mark A.|last4=Hartl|first4=Daniel L.|date=2006-04-07|title=Darwinian Evolution Can Follow Only Very Few Mutational Paths to Fitter Proteins|journal=Science|language=en|volume=312|issue=5770|pages=111–114|doi=10.1126/science.1123539|issn=0036-8075|pmid=16601193|bibcode=2006Sci...312..111W |s2cid=21186834}}</ref> and malaria.<ref>{{Cite journal|last1=Park|first1=Daniel J.|last2=Lukens|first2=Amanda K.|last3=Neafsey|first3=Daniel E.|last4=Schaffner|first4=Stephen F.|last5=Chang|first5=Hsiao-Han|last6=Valim|first6=Clarissa|last7=Ribacke|first7=Ulf|last8=Tyne|first8=Daria Van|last9=Galinsky|first9=Kevin|date=2012-08-07|title=Sequence-based association and selection scans identify drug resistance loci in the Plasmodium falciparum malaria parasite|journal=Proceedings of the National Academy of Sciences|language=en|volume=109|issue=32|pages=13052–13057|doi=10.1073/pnas.1210585109|issn=0027-8424|pmid=22826220|pmc=3420184|bibcode=2012PNAS..10913052P |doi-access=free}}</ref> His lab identified the ''Mariner'' transposon.<ref>{{Cite journal|last=Hartl|first=Daniel L.|date=2001-02-01|title=Discovery of the Transposable Element Mariner|url=http://www.genetics.org/content/157/2/471|journal=Genetics|language=en|volume=157|issue=2|pages=471–476|doi=10.1093/genetics/157.2.471|issn=0016-6731|pmid=11156971|pmc=1461507}}</ref> As of 2017 research at the Hartl Laboratory at Harvard University focused on evolutionary genomics, molecular evolution, and population genetics.<ref name=":2">{{cite web |url= https://hartlgroup.oeb.harvard.edu/people/daniel-hartl|title= Daniel Hartl|last= Hartl|first= Daniel|website= Hartl Laboratory|publisher= Harvard University |access-date= 22 August 2017}}</ref> Hartl's ongoing research includes malaria research, which his connected to his work on antibiotic resistance.<ref name=":3" />
== Author == Hartl is the author of a widely used textbook on population genetics<ref>{{Cite book|title=Principles of population genetics|last=L.|first=Hartl, Daniel|date=2007|publisher=Sinauer Associates|others=Clark, Andrew G., 1954-|isbn=978-0878933082|edition= 4th |location=Sunderland, Mass.|oclc=75087956}}</ref> and an introductory text on genetics.<ref>{{Cite book|title=Genetics : analysis of genes and genomes|last=L.|first=Hartl, Daniel|others=Cochrane, Bruce|year=2019|isbn=9781284122930|edition= Ninth |location=Burlington, MA|oclc=996709835}}</ref>
== Awards and honors == Hartl is the 2019 recipient of the Thomas Hunt Morgan Medal from the Genetics Society of America (GSA). The award recognizes a lifetime of achievement in genetics research.<ref name=":3">{{Cite web|url=https://www.antigotimes.com/2019/04/08/genetics-society-of-america-awards-2019-thomas-hunt-morgan-medal-to-daniel-hartl/|title=Genetics Society of America Awards 2019 Thomas Hunt Morgan Medal to Daniel Hartl|date=2019-04-08|website=Antigo Times|language=en-US|access-date=2019-05-02}}</ref>
He was elected President of the Genetics Society of America for 1989.<ref>{{cite web|url=http://www.genetics-gsa.org/about/past_officers.shtml|title=Past and Present GSA Officers|publisher=GSA|accessdate=28 November 2018|archive-url=https://web.archive.org/web/20181204095737/http://www.genetics-gsa.org/about/past_officers.shtml|archive-date=4 December 2018|url-status=dead}}</ref> He is an elected fellow of the National Academy of Sciences and the American Academy of Arts and Sciences.<ref name=":3" />
== Published works == * Daniel L Hartl, Andrew G Clark, Andrew G Clark. ''[https://scholar.google.com/citations?view_op=view_citation&hl=en&user=h_MOIUUAAAAJ&citation_for_view=h_MOIUUAAAAJ:u5HHmVD_uO8C Principles of population genetics]'', 4th ed. 1997. Sinauer Associates (Sunderland, Massachusetts). * H Ochman, A S Gerber, D L Hartl. "[https://scholar.google.com/citations?view_op=view_citation&hl=en&user=h_MOIUUAAAAJ&citation_for_view=h_MOIUUAAAAJ:u-x6o8ySG0sC Genetic applications of an inverse polymerase chain reaction]". ''Genetics''. November 1, 1988 vol. 120 no. 3 621–623. * Hartl, D. L. ''[https://scholar.google.com/citations?view_op=view_citation&hl=en&user=h_MOIUUAAAAJ&citation_for_view=h_MOIUUAAAAJ:d1gkVwhDpl0C A primer of population genetics]''. 1988. Sinauer Associates (Sunderland, Massachusetts). {{ISBN|9780878933013}}.
== References == <!-- Inline citations added to your article will automatically display here. See https://en.wikipedia.org/wiki/WP:REFB for instructions on how to add citations. --> {{reflist|30em}}
==External links== * {{Google scholar id}}
{{Authority control}}
{{DEFAULTSORT:Hartl, Daniel L}} Category:1943 births Category:Living people Category:21st-century American biologists Category:University of Wisconsin–Madison College of Agricultural and Life Sciences alumni Category:Harvard Faculty of Arts and Sciences faculty Category:People from Antigo, Wisconsin Category:University of Minnesota faculty Category:Purdue University faculty Category:Washington University in St. Louis faculty Category:University of California, Berkeley fellows Category:20th-century American biologists Category:University of Wisconsin–Stevens Point alumni