{{Short description|Enzyme}} {{Infobox enzyme | Name = Colneleate synthase | EC_number = 4.2.1.121 | CAS_number = | GO_code = | image = | width = | caption = }} '''Colneleate synthase''' ({{EnzExplorer|4.2.1.121}}, ''9-divinyl ether synthase'', ''9-DES'', ''CYP74D'', ''CYP74D1'', ''CYP74 cytochrome P-450'', ''DES1'') is an enzyme with systematic name ''(8E)-9-((1E,3E)-nona-1,3-dien-1-yloxy)non-8-enoate synthase''.<ref>{{cite journal | vauthors = Stumpe M, Kandzia R, Göbel C, Rosahl S, Feussner I | title = A pathogen-inducible divinyl ether synthase (CYP74D) from elicitor-treated potato suspension cells | journal = FEBS Letters | volume = 507 | issue = 3 | pages = 371–6 | date = November 2001 | pmid = 11696374 | doi = 10.1016/s0014-5793(01)03019-8 | doi-access = free }}</ref><ref>{{cite journal | vauthors = Itoh A, Howe GA | title = Molecular cloning of a divinyl ether synthase. Identification as a CYP74 cytochrome P-450 | journal = The Journal of Biological Chemistry | volume = 276 | issue = 5 | pages = 3620–7 | date = February 2001 | pmid = 11060314 | doi = 10.1074/jbc.m008964200 | doi-access = free }}</ref><ref>{{cite journal | vauthors = Fammartino A, Cardinale F, Göbel C, Mène-Saffrané L, Fournier J, Feussner I, Esquerré-Tugayé MT | title = Characterization of a divinyl ether biosynthetic pathway specifically associated with pathogenesis in tobacco | journal = Plant Physiology | volume = 143 | issue = 1 | pages = 378–88 | date = January 2007 | pmid = 17085514 | pmc = 1761965 | doi = 10.1104/pp.106.087304 }}</ref><ref>{{cite journal | vauthors = Hamberg M | title = Hidden stereospecificity in the biosynthesis of divinyl ether fatty acids | journal = The FEBS Journal | volume = 272 | issue = 3 | pages = 736–43 | date = February 2005 | pmid = 15670154 | doi = 10.1111/j.1742-4658.2004.04510.x | doi-access = free }}</ref> This enzyme catalyses the following chemical reaction
: (9''S'',10''E'',12''Z'')-9-hydroperoxyoctadeca-10,12-dienoate <math>\rightleftharpoons</math> :: (8''E'')-9-[(1''E'',3''Z'')-nona-1,3-dien-1-yloxy]non-8-enoate + H<sub>2</sub>O
This enzyme is a heme-thiolate protein (P450).
== References == {{reflist}}
== External links == * {{MeshName|Colneleate+synthase}}
{{Cytochrome P450}} {{Portal bar|Biology|border=no}}
Category:EC 4.2.1