'''Cosme''' is a given name and surname. Notable people with the name include:

{{TOC right}} ==Given name== *Cosme (footballer) (1927–2011), Spanish footballer *Cosme Argerich (1758–1820), Argentinian military physician *Cosme Correa ({{floruit|pfx-lk=abbr}} 1540s), Portuguese nobleman and colonizer of Bombay *Cosme Damián de Churruca y Elorza (1761–1805), Spanish nobleman and soldier *Cosme Damião (1885–1947), Portuguese football player and coach *Cosme de Torres (1510–1570), Spanish Jesuit missionary *Cosme Delgado (died 1596), Portuguese Renaissance composer *Cosme García Sáez (1818–1874), Spanish inventor *Cosme Martins (born 1959), Brazilian painter *Cosmé McMoon (1901–1980), American pianist and composer *Cosme Prenafeta (born 1971), Spanish volleyball player *Cosme Saavedra (1901–1967), Argentine cyclist *Cosme San Martín (died 1906), Chilean painter *Cosme Rivera (born 1976), Mexican boxer *Cosme Torres Espinoza ({{floruit|pfx-lk=abbr}} 2000s), Cuban diplomat *Cosmé Tura (1430–1495), Italian painter *Cosme de Villiers (1683–1758), French bibliographer

==Surname== *Eusebia Cosme (1908–1976), Afro-Cuban poetry reciter and actress *Fernando Nascimento Cosme (born 1983), Brazilian futsal player *Gilbert Cosme (born 1975), Puerto Rican wrestler better known by his ring names, El Mesías and Ricky Banderas *Laura Cosme (born 1992), Colombian footballer *Niccolo Cosme (born 1980), Filipino photographer *Pierre Cosme (born 1965), French historian *Wilberto Cosme (born 1984), Colombian professional footballer *Wilma Cosmé (born 1966), a Puerto Rican-American singer better known by her stage name Sa-Fire

{{Given name|type=both}}