{{Short description|Part of the developing heart}} {{Infobox embryology | Name = Bulbus cordis | Latin = bulbus cordis | Image = Gray466.png | Caption = Heart showing expansion of the [[Atrium (heart)|atria]]. | Image2 = Gray469.png | Caption2 = Diagrams to illustrate the transformation of the bulbus cordis. Ao. [[Truncus arteriosus]]. Au. [[Atrium (heart)|Atrium]]. B. Bulbus cordis. RV. [[Right ventricle]]. LV. [[Left ventricle]]. P. [[Pulmonary artery]]. | System = | CarnegieStage = 9 | Precursor = | GivesRiseTo = smooth parts of [[right ventricle]], [[left ventricle]] }} The '''bulbus cordis''' (the '''bulb of the heart''') is a part of the [[heart development|developing heart]] that lies ventral to the [[primitive ventricle]] after the [[heart]] assumes its S-shaped form. The superior end of the bulbus cordis is also called the '''conotruncus'''.<ref>{{cite book|last1=Larsen|first1=William J|title=Human Embryology|date=2001|publisher=Elsevier|isbn=0-443-06583-7|page=160|edition=3rd}}</ref>
== Structure == In the early [[tubular heart]], the bulbus cordis is the major outflow pathway.<ref name=":0">{{Citation|last=Carlson|first=Bruce M.|title=Development of the Heart|date=2014|url=http://www.sciencedirect.com/science/article/pii/B978012801238305460X|work=Reference Module in Biomedical Sciences|publisher=Elsevier|language=en|isbn=978-0-12-801238-3|access-date=2021-01-05}}</ref> It receives blood from the [[primitive ventricle]], and passes it to the [[truncus arteriosus]].<ref name=":0" /><ref name=":1">{{Citation|last1=De Iuliis|first1=Gerardo|title=Chapter 6 – The Frog|date=2011-01-01|url=http://www.sciencedirect.com/science/article/pii/B9780123750600000061|work=The Dissection of Vertebrates |edition=2nd|pages=127–145|editor-last=De Iuliis|editor-first=Gerardo|place=Boston|publisher=Academic Press|language=en|isbn=978-0-12-375060-0|access-date=2021-01-05|last2=Pulerà|first2=Dino|editor2-last=Pulerà|editor2-first=Dino}}</ref> After [[Heart development|heart looping]], it is located slightly to the left of the ventricle.<ref name=":1" />
=== Development === {{Further|Heart development}} The early bulbus cordis is formed by the fifth week of [[embryonic development|development]].<ref>{{Citation|last=Belmont|first=John W.|title=Chapter 33 – Genetic and Developmental Basis of Congenital Cardiovascular Malformations|date=2015|url=http://www.sciencedirect.com/science/article/pii/B9780124059450000338|work=Principles of Developmental Genetics|edition= 2nd |pages=607–633|editor-last=Moody|editor-first=Sally A.|place=Oxford|publisher=Academic Press|language=en|isbn=978-0-12-405945-0|access-date=2021-01-05}}</ref> The truncus arteriosus is derived from it later.<ref name=":0" />
The adjacent walls of the bulbus cordis and ventricle approximate, fuse, and finally disappear, and the bulbus cordis now communicates freely with the [[right ventricle]], while the junction of the bulbus with the [[truncus arteriosus (embryology)|truncus arteriosus]] is brought directly ventral to and applied to the [[atrial canal]].
By the upgrowth of the [[ventricular septum]] the bulbus cordis is separated from the [[left ventricle]], but remains an integral part of the right ventricle, of which it forms the [[Infundibulum (heart)|infundibulum]].
Together, the bulbus cordis and the primitive ventricle give rise to the [[Ventricle (heart)|ventricle]]s of the formed heart.
== Other animals == The bulbus cordis is shared in the development of many animals, including [[frog]]s<ref name=":1" /> and [[fish]].<ref>{{Citation|last1=Zaccone|first1=G.|title=Design and Physiology of the Heart {{!}} Intracardiac Neurons and Neurotransmitters in Fish|date=2011|url=http://www.sciencedirect.com/science/article/pii/B9780123745538002276|encyclopedia=Encyclopedia of Fish Physiology|pages=1067–1072|editor-last=Farrell|editor-first=Anthony P.|place=San Diego|publisher=Academic Press|language=en|isbn=978-0-08-092323-9|access-date=2021-01-05|last2=Marino|first2=F.|last3=Zaccone|first3=D.}}</ref>
==Additional images== <gallery> File:Gray460.png|Head of chick embryo of about thirty-eight hours' incubation, viewed from the ventral surface. X 26 File:Gray461.png|Diagram to illustrate the simple tubular condition of the heart. File:Gray462.png|Heart of human embryo of about fourteen days. File:Gray977.png|Human embryo about fifteen days old. Brain and heart represented from right side. Digestive tube and yolk sac in median section. </gallery>
==References== {{Gray's}} {{reflist}}
==External links== * {{EmbryologyTemple|Heart98/heart97b/sld023}} * {{EmbryologyUNC|cardev|017}} * {{LoyolaMedEd|GrossAnatomy/thorax0/Heart_Development/AtrioVent.html}} * {{cite book |title= Cardiac development |last= Kirby|first= Margaret L.|year= 2007|publisher= [[Oxford University Press]] |isbn= 978-0-19-517819-7|page= 119|url= https://books.google.com/books?id=fjhCQ-QbtbsC|access-date=20 April 2011}}
{{Development of circulatory system}}
{{Portal bar|Anatomy}} [[Category:Embryology of cardiovascular system]]
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