{{Promotional|date=September 2025}}{{Infobox company | name = Codex Labs | type = Private | industry = Biotechnology, Dermatology, Wellness | founded = 2018 | founder = Barbara Paldus | hq_location = Silicon Valley, California, United States | key_people = Barbara Paldus (Founder, CEO) | products = OTC skincare, medical foods, dietary supplements, microbiome | website = {{URL|https://www.codexlabscorp.com/}} }}
'''Codex Labs''' is a plant-biotechnology company focused on skin-gut-brain-biome solutions for skin conditions (acne, eczema, rosacea, and psoriasis) based in Silicon Valley, California.<ref name=":0">{{Cite web |last=Pringuay |first=Valentin |date=2023-12-21 |title=Comment la marque internationale Codex Labs s'est retrouvée à réaliser ses tests à Lyon |url=https://www.maddyness.com/2023/12/21/comment-la-marque-tcheque-codex-labs-sest-retrouvee-a-realiser-ses-tests-a-lyon/ |access-date=2025-02-04 |website=Maddyness - Le média pour comprendre l'économie de demain |language=fr-FR}}</ref> The company develops clinically proven topicals and ingestibles for integrative dermatologists and naturopaths based on biotechnology and botanical actives.<ref name=":1">{{Cite web |last=Robertson |first=Anna |date=2022-12-09 |title=After dealing with her son's allergies, this mom created the first skincare line with 'nutrition labels' on its products |url=https://www.thecooldown.com/green-business/codex-labs-barb-paldus-labels/ |access-date=2025-02-04 |website=The Cool Down |language=en-US}}</ref><ref>{{Cite web |last=Šmýkal |first=Mário |date=2025-01-27 |title=Češka predala firmu za päť miliárd korún. Jej kozmetika teraz mení ľudské životy |url=https://www.forbes.sk/ceska-predala-firmu-za-pat-miliard-korun-jej-kozmetika-teraz-meni-ludske-zivoty/ |access-date=2025-02-03 |website=Forbes |language=sk-SK}}</ref>
== History == Codex Labs was founded by Barbara Paldus<ref>{{Cite web |last=Česko |first=Forbes |date=2023-06-04 |title=Dcéra českých emigrantov založila 225-miliónovú firmu. A začala revolúciu v kozmetike |url=https://www.forbes.sk/dcera-ceskych-emigrantov-predala-firmu-za-225-milionov-dolarov-a-zacala-revoluciu-v-kozmetike/?srsltid=AfmBOor5rnT0Jqt7j3Dq6OMXl-u0F_s1qKFPRLegI5LHbOLChK4t03Ns |access-date=2025-02-04 |website=Forbes |language=sk-SK}}</ref> in 2018 with a focus on developing phenoxyethanol-free skincare product that preserves the native skin microbiome.<ref name=":1" /><ref name=":0" /><ref>{{Cite web |last=Poljakov |first=Nikita |date=2024-02-20 |title=Kosmetický průmysl by věda zničila, říká Barbara Paldus z Codex Labs |url=https://www.e15.cz/podcasty/medicast/veda-by-kosmeticky-prumysl-znicila-proto-se-ji-znacky-brani-rika-barbara-paldus-z-codex-labs-1411524 |access-date=2025-02-04 |website=e15.cz |language=cs}}</ref><ref>{{Cite web |last=Zeller |first=Nina |date=2024-10-12 |title=So halten wir das Haut-Mikrobiom gesund – Tipps für eine strahlende Haut und starke Schutzbarriere Mit diesen einfachen Schritten zu makellos gepflegten Füßen |url=https://marieclaire.de/beauty/so-halten-sie-das-haut-mikrobiom-gesund/ |access-date=2025-02-04 |website=Marie Claire Germany |language=de}}</ref> In its early stages, Codex Labs acquired Irish skincare company Bia Beauty and partnered with the French Eurofins Dermscan laboratory in Lyon for experimentation and clinical trials.<ref name=":0" /> It also partnered with MyMicrobiome to certify all of its skincare products as microbiome-supporting. Codex launched its first skincare products in 2019 and its first supplements in 2023.<ref>{{Cite web |last=Pringuay |first=Valentin |date=2023-12-21 |title=Comment la marque internationale Codex Labs s'est retrouvée à réaliser ses tests à Lyon |url=https://www.maddyness.com/2023/12/21/comment-la-marque-tcheque-codex-labs-sest-retrouvee-a-realiser-ses-tests-a-lyon/ |access-date=2025-02-03 |website=Maddyness - Le média pour comprendre l'économie de demain |language=fr-FR}}</ref><ref>{{Cite web |date=2024-02-20 |title=Kosmetický průmysl by věda zničila, říká Barbara Paldus z Codex Labs |url=https://www.e15.cz/podcasty/medicast/veda-by-kosmeticky-prumysl-znicila-proto-se-ji-znacky-brani-rika-barbara-paldus-z-codex-labs-1411524 |access-date=2025-02-03 |website=e15.cz |language=cs}}</ref>
In 2019, the company developed and patented its PreservX system, a novel biotech-ferment-based preservative that supports the natural skin microbiome.<ref name=":1" /><ref>{{Cite patent|number=US10721937B1|title=Preservative systems and compositions and methods incorporating same|gdate=2020-07-28|invent1=Cornell|invent2=Paldus|inventor1-first=Marc|inventor2-first=Barbara A.|url=https://patents.google.com/patent/US10721937B1/en}}</ref> It is a combination of four edible ingredients designated as GRAS (Generally Recognized As Safe) by the US FDA: edible organic acids, lactobacillus ferment, coconut oil ferment, and biotech propanediol.<ref>{{Cite web |last=Wray |first=Julia |date=2020-08-03 |title=Codex Beauty patents edible personal care preservation system |url=https://cosmeticsbusiness.com/codex-beauty-patents-edible-personal-care-preservation-system--168561 |access-date=2025-02-04 |website=cosmeticsbusiness.com |language=en}}</ref><ref name=":3">{{Cite web |date=2023-06-08 |title=Codex Labs : Quand la science des plantes fleurit au service de la peau |url=https://madame.lefigaro.fr/business/codex-labs-quand-la-science-des-plantes-fleurit-au-service-de-la-peau-20230608 |access-date=2025-02-04 |website=Madame Figaro |language=fr}}</ref> Later that year, Codex Labs introduced the MyMicrobiome-certified Bia collection, which focused on deep hydration, water retention, and turnover of dry skin layers.<ref>{{Cite web |last=Schott Ledes |first=Christine |date=2019-06-29 |title=Codex Beauty Launches Bia Skincare |url=https://www.thebeautyinfluencers.com/2019/06/29/codex-2/ |access-date=2025-02-04 |website=The Beauty Influencers |language=en-US}}</ref> The BiaComplex patent was issued in 2020.<ref>{{Cite web |last=Behrens |first=Michele |date=2020-08-14 |title=Codex Beauty Highlights Patents for BiaComplex and PreservX |url=https://www.cosmeticsandtoiletries.com/formulas-products/skin-care/news/21843557/codex-beauty-highlights-patents-for-biacomplex-and-preservx |access-date=2025-02-04 |website=Cosmetics & Toiletries |language=en-us}}</ref><ref>{{Cite patent|number=US20200121744A1|title=Compositions and methods for treating skin diseases and maintaining healthy skin|gdate=2020-04-23|invent1=Li|invent2=Barnard|invent3=Shi|inventor1-first=Huiying|inventor2-first=Emma|inventor3-first=Baochen|url=https://patents.google.com/patent/US20200121744A1/en}}</ref> The Antü collection, launched in 2020 and also MyMicrobiome-certified, focused on protecting and strengthening the skin barrier against the exposome, re-densifying the epidermis, and alleviating damage caused by UV light.<ref>{{Cite web |date=2021-02-23 |title=Codex Beauty Labs to Launch Microbiome-friendly Skin Care Collection, Antü |url=https://www.cosmeticsandtoiletries.com/formulas-products/skin-care/news/21844071/codex-beauty-labs-to-launch-microbiome-friendly-skin-care-collection-antu |access-date=2025-02-04 |website=Cosmetics & Toiletries |language=en-us}}</ref> The AntuComplex and skin protectant patents were issued in 2021.<ref>{{Cite patent|number=CN113905717A|title=Natural skin care compositions and methods for treating oxidative stress and restoring skin health|gdate=2022-01-07|invent1=M·康奈尔|invent2=B·A·帕尔杜斯|invent3=J·I·萨纽埃萨塞普尔维达|url=https://patents.google.com/patent/CN113905717A/en}}</ref>
The Shaant collection, introduced in 2022 (cosmetic) and 2023 (OTC), controlled sebum production, reduced redness, and mitigated the acne inflammasome for acne-prone skin.<ref name=":4">{{Cite journal |last1=Nong |first1=Yvonne |last2=Gahoonia |first2=Nimrit |last3=Rizzo |first3=Julianne |last4=Burney |first4=Waqas |last5=Sivamani |first5=Raja K. |last6=Maloh |first6=Jessica |date=January 2023 |title=Prospective Evaluation of a Topical Botanical Skin Care Regimen on Mild to Moderate Facial and Truncal Acne and Mood |journal=Journal of Clinical Medicine |language=en |volume=12 |issue=4 |pages=1484 |doi=10.3390/jcm12041484 |issn=2077-0383 |doi-access=free|pmid=36836020 |pmc=9966061 }}</ref> The Shaant face/body scrubs were the first OTC acne products on the market to be MyMicrobiome-certified.<ref>{{Cite web |date=2022-07-25 |title=Codex Beauty Labs Launches Line to Support the Skin's Microbiome |url=https://www.beautypackaging.com/issues/temp2022/view_breaking-news/codex-beauty-labs-launches-line-to-support-the-skins-microbiome/ |access-date=2025-02-04 |website=Beauty Packaging}}</ref> The ShaantComplex patent was issued in 2022.<ref>{{Cite web |last=Esposito |first=Christine |date=2022-11-01 |title=Codex Labs Earns Fifth US Patent for Skincare Technology |url=https://www.happi.com/breaking-news/codex-labs-earns-fifth-us-patent-for-skincare-tech/ |access-date=2025-02-04 |website=Happi |language=en-US}}</ref><ref>{{Cite patent|number=US11484489B1|title=Skin care compositions and methods for regulating sebum production|gdate=2022-11-01|invent1=Cornell|invent2=Paldus|inventor1-first=Marc|inventor2-first=Barbara A.|url=https://patents.google.com/patent/US11484489B1/en}}</ref> In 2025, the company began testing its first functional fragrance (Cocoon) in Europe for mood modulation and stress reduction.<ref>{{Cite web |date=22 December 2024 |title=Codex Labs predstavuje COCOON - Trendy |url=https://www.top-fashion.sk/codex-labs-predstavuje-cocoon |access-date=2025-02-04 |website=Top Fashion |language=sk}}</ref><ref>{{Cite web |title=Trápí vás ekzém? Poznejte kosmetiku, která vás hýčká poznatky z vědy |url=https://www.elle.cz/promotion/ellephoria/trapi-vas-ekzem-poznejte-kosmetiku-ktera-vas-hycka-poznatky-z-vedy?utm_campaign=pr_article |access-date=2025-02-04 |website=www.elle.cz |language=cs}}</ref> Codex Labs' products were also approved by the National Psoriasis Foundation in 2022 as irritation-free products that are safe for sensitive skin suffering from psoriasis.<ref name=":1" />
In April 2025, Codex Labs’ Bia Eczema Relief Lotion was awarded Microbiome-friendly Certification (MyMicrobiome Standard)<ref>{{cite web |date=11 April 2025 |title=Codex Labs Lotion is First Eczema OTC Topical to Achieve Microbiome-Friendly Certification |url=https://www.dermatologytimes.com/view/codex-labs-lotion-is-first-eczema-otc-topical-to-achieve-microbiome-friendly-certification?utm_source=chatgpt.com |access-date=8 September 2025 |work=Dermatology Times |publisher=MJH Life Sciences}}</ref> and the National Eczema Association Seal of Acceptance.<ref>{{cite web |date=23 April 2025 |title=Codex Labs Bia Ultra-Hydrating Soothing Lotion Is Awarded Seal of Acceptance from National Eczema Association and Microbiome-Friendly Certification |url=https://finance.yahoo.com/news/codex-labs-bia-ultra-hydrating-070000470.html?guccounter=1&guce_referrer=aHR0cHM6Ly93d3cuZ29vZ2xlLmNvbS8&guce_referrer_sig=AQAAAJuAykYkteESz5PiXyxWsaWMs8eYlCGyythNlzhHVFBX17k_CFcMUlg5WqUm9YzQiyz0TWQyZcuA-CaBmYetbB6Twr7vuxa9QuxYHLq69_TVzSyGWRh0dnYiy_Y91X_ELgwxZaL1cToMwqwsAKQvxY_v_LtDfgSP9P_vwWrSzjg9 |access-date=8 September 2025 |work=GlobeNewswire |publisher=Yahoo Finance}}</ref> In May, the company was granted U.S. Patent No. 12,194,068 for Shaant ClearSkin Probiotic 2.0, an oral synbiotic supplement aimed at managing oily and acne-prone skin.<ref>{{Cite web |date=2025-05-20 |title=Shaant ClearSkin Probiotic Granted Patent for Acne Relief |url=https://www.dermatologytimes.com/view/shaant-clearskin-probiotic-granted-patent-for-acne-relief |access-date=2025-09-08 |website=Dermatology Times |language=en}}</ref><ref>{{cite web |date=20 May 2025 |title=Codex Labs Shaant ClearSkin Probiotic 2.0 Supplement for Oily and Acne-Prone Skin Is Awarded U.S. Patent |url=https://finance.yahoo.com/news/codex-labs-shaant-clearskin-probiotic-130000909.html |access-date=8 September 2025 |work=GlobeNewswire |publisher=Yahoo Finance}}</ref>
== Products == In addition to skincare products like BIA, ANTÜ and SHAANT,<ref>{{Cite web |last=GreyB |first=Team |date=2024-08-22 |title=5 Microbiome-Friendly Skincare Startups to Watch in 2025 |url=https://www.greyb.com/blog/microbiome-friendly-skincare-startups/ |access-date=2025-02-04 |website=GreyB |language=en-US}}</ref> the company has developed dietary supplements to address gut barrier integrity, mucosal function, inflammation, and microbiome balance. All products are clinically tested, microbiome-friendly, and certified vegan, cruelty-free, and sustainable.<ref name=":1" /><ref name=":4" />
== References == {{Reflist}} Category:American companies established in 2018 Category:Companies based in Silicon Valley Category:Personal care brands Category:Biotechnology companies of the United States