{{chembox | verifiedrevid = 409701857 | Name = | Reference = <ref>{{RubberBible62nd|page=B-91}}.</ref> | ImageFile = cesium acetate.svg | ImageSize = 120px | ImageCaption = Structural formula | ImageFile1 = Caesiumacetat.png | ImageFileL1 = Acetate-anion-3D-balls.png | ImageFileR1 = Caesium-3D.png | ImageSize1 = 240px | ImageCaption1 = Unit cell of anhydrous caesium acetate. | ImageAlt1 = anhydrous caesium acetate crystallizes in a hexagonal unit cell. | PIN = Caesium acetate | OtherNames = Cesium acetate | Section1 = {{Chembox Identifiers | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 141192 | InChI = 1/C2H4O2.Cs/c1-2(3)4;/h1H3,(H,3,4);/q;+1/p-1 | InChIKey = ZOAIGCHJWKDIPJ-REWHXWOFAB | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C2H4O2.Cs/c1-2(3)4;/h1H3,(H,3,4);/q;+1/p-1 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = ZOAIGCHJWKDIPJ-UHFFFAOYSA-M | CASNo_Ref = {{cascite|correct|CAS}} | CASNo = 3396-11-0 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = M74D2UJ8C9 | PubChem = 5152919 | SMILES = [Cs+].[O-]C(=O)C }} | Section2 = {{Chembox Properties | C=2 | H=3 | O=2 | Cs=1 | MolarMass = 191.949 g/mol | Appearance = colourless, hygroscopic | Density = 2.423 g/cm<sup>3</sup>, solid | MeltingPtC = 194 | BoilingPtC = 945 | Solubility = 945.1 g/100 g (−2.5&nbsp;°C)<br/>1345.5 g/100 ml (88.5&nbsp;°C) }} | Section3 = | Section4 = {{Chembox Structure | LattConst_ref = <ref name="crystal structure">{{Cite journal |doi = 10.1002/zaac.19936190823|title = Kristallstruktur von Caesiumacetat, Cs(CH3COO)|journal = Zeitschrift für Anorganische und Allgemeine Chemie|volume = 619|issue = 8|pages = 1462–1464|year = 1993|last1 = Lossin|first1 = Adalbert|last2 = Meyer|first2 = Gerd}}</ref> | Structure_ref = <ref name="crystal structure" /> | CrystalStruct = Primitive hexagonal | LattConst_a = 1488.0 pm | LattConst_c = 397.65 pm | SpaceGroup = P6/m, No. 175 | UnitCellFormulas = 6 | UnitCellVolume = 76.542 cm<sup>3</sup>·mol<sup>−1</sup> }} | Section5 = | Section6 = | Section7 = {{Chembox Hazards | FlashPt = Non-flammable | GHS_ref = <ref>{{Cite web |last=PubChem |title=Cesium acetate |url=https://pubchem.ncbi.nlm.nih.gov/compound/5152919 |access-date=2026-01-18 |website=pubchem.ncbi.nlm.nih.gov |language=en}}</ref> | GHSPictograms = {{GHS07}}{{GHS08}} | GHSSignalWord = Warning | HPhrases = {{H-phrases|H302|H319|H361f|H373}} | PPhrases = {{P-phrases|P203|P260|P264|P264+P265|P270|P280|P301+P317|P305+P351+P338|P318|P319|P330|P337+P317|P405|P501}} }} | Section8 = {{Chembox Related | OtherAnions = Caesium formate | OtherCations = Lithium acetate<br/>Sodium acetate<br/>Potassium acetate<br/>Rubidium acetate }} }}

'''Caesium acetate''' or '''cesium acetate''' is an ionic caesium compound with the molecular formula CH<sub>3</sub>COOCs. It is a white solid that may be formed by the reaction of caesium hydroxide or caesium carbonate with acetic acid.<ref name="e-EROS">{{Citation|last=Yode|first=Ryan|title=Cesium Acetate|date=2015|url=https://onlinelibrary.wiley.com/doi/abs/10.1002/047084289X.rn01845|encyclopedia=Encyclopedia of Reagents for Organic Synthesis|pages=1–11|publisher=John Wiley & Sons|language=en|doi=10.1002/047084289x.rn01845|isbn=978-0-470-84289-8|access-date=2020-07-21|url-access=subscription}}</ref>

== Uses == It is used in organic synthesis. One example is in the Perkin synthesis: the formation of unsaturated cinnamic-type acids by the condensation of aromatic aldehydes with fatty acids. Replacement of the commonly used sodium acetate with caesium acetate has been shown to improve yields by up to 10 times.<ref name="e-EROS"/><ref>{{citation|last1=Koepp|first1=E.|title=Perkin-Synthese mit Cäsiumacetat|journal=Synthesis|volume=1987|issue=2|pages=177–179|year=1987|doi=10.1055/s-1987-27880|last2=Vögtle|first2=F.}}.</ref>

It is often used to invert secondary alcohols. After converting the alcohol to a good leaving group, such as a mesylate, direct S<sub>N</sub>2 substitution with the acetate produces the O-acetate with inverted stereochemistry, which can be converted back to a hydroxyl group.<ref name="e-EROS"/>

Caesium acetate is occasionally used instead of caesium formate in petroleum drilling fluids.<ref>{{Cite web |title=cesium_acetate |url=https://glossary.slb.com/en/terms/c/cesium_acetate |access-date=2026-01-18 |website=glossary.slb.com |language=en}}</ref>

==References== {{Reflist}}

==Further reading== *{{citation | last1 = Torisawa | first1 = Yasuhiro | last2 = Okabe | first2 = Hiromitsu | last3 = Ikegami | first3 = Shiro | title = Efficient Inversions of Secondary Alcohols using Cesium Acetate and 18-Crown-6 | journal = Chem. Lett. | year = 1984 | volume = 13 | issue = 9 | pages = 1555–56 | doi = 10.1246/cl.1984.1555| doi-access = free }}.

==External links== *[https://web.archive.org/web/20080511192739/http://specialmetals.chemetall.com/pdf/Cesium_Acetate_pure.pdf Caesium acetate factsheet from Chemetall GmbH]

{{Caesium compounds}} {{Acetates}}

Category:Caesium compounds Category:Acetates Category:Reagents for organic chemistry