{{Short description|Genus of bacteria}} {{Automatic taxobox | taxon = Cedecea | authority = Grimont et al. 1981 | subdivision_ranks = Species | subdivision = * ''C. davisae'' * ''C. lapegei'' * ''Cedecea'' species 001 (also known as ''Cedecea'' species 3) * ''C. neteri'' (formerly known as ''Cedecea'' species 4 or ''Cedecea'' species 002) * ''Cedecea'' species 012 (also known as ''Cedecea'' species 5) }}
'''''Cedecea''''' is a genus of extremely rare bacteria of the family Enterobacteriaceae.<ref name=Enterobacteria>{{cite book |title= The Enterobacteria|last= Janda|first= J. Michael|author2=Sharon L. Abbott|year= 2006|publisher= ASM Press|location= Washington, D.C.|isbn=978-1-55581-342-0 |page=411 |edition=2nd}}</ref> The name of this genus was derived from CDC, the abbreviation for the Centers for Disease Control where the initial members of this genus were discovered.<ref>{{cite journal |author1=P. Grimont |author2=F. Grimont |author3=J. Farmer III |author4=M. Asbury | title = ''Cedecea davisae'' gen. nov., sp. nov. and ''Cedecea lapagei'' sp. nov., New ''Enterobacteriaceae'' from Clinical Specimens | journal = Int J Syst Bacteriol | year = 1981 | volume = 31 | pages = 317–326 | doi = 10.1099/00207713-31-3-317 | issue = 3| doi-access = free }}</ref> This genus resembles no other group of Enterobacteriaceae.<ref name="Grimont">Grimont, P. A. D., Grimont, F., Farmer III, J. J., and Asbury, M. A. (1981). [https://archive.today/20130416015055/http://ijs.sgmjournals.org/content/31/3/317.abstract ''Cedecea davisae'' gen. nov., sp. nov. and ''Cedecea lapagei'' sp. nov., New ''Enterobacteriaceae'' from clinical specimens.] ''International Journal of Systematic Bacteriology'' '''31''', 317-326.</ref> ''Cedecea'' bacteria are Gram-negative, bacillus in shape, motile, nonencapsulated, and non-spore-forming.<ref name="Mawardi">Mawardi, H., Pavlakis, M., Mandelbrot, D., Woo, S. B. (2010). [http://www.mdlinx.com/infectious-disease/news-article.cfm/3168565/sirolimus Sirolimus oral ulcer with ''Cedecea davisae'' superinfection.]{{Dead link|date=February 2026 |bot=InternetArchiveBot }} ''Transpl Infect Dis'' '''12''', 446-450.</ref><ref name="Abate">Abate, G., Qureshi, S., and Mazumder, S. A. (2011). [http://www.mendeley.com/research/cedecea-davisae-bacteremia-neutropenic-patient-acute-myeloid-leukemia/ ''Cedecea davisae'' bacteremia in a neutropenic patient with acute myeloid leukemia.] ''Journal of Infection'' '''63''', 83-85.</ref> The strains of ''Cedecea'' appear to be similar to those of ''Serratia''. Both ''Cedecea'' and ''Serratia'' are lipase positive and resistant to colistin and cephalothin; however, ''Cedecea'' is unable to hydrolyze gelatin or DNA.<ref name="Abate"/><ref name="Farmer">Farmer III, J. J., Sheth, N. K., Hudzinski, J. A., Rose, H. D., Asbury, M. F. (1982). [http://www.mendeley.com/research/bacteremia-due-cedecea-neteri-sp-nov/ Bacteremia due to ''Cedecea neteri'' sp. nov.] ''Journal of Clinical Microbiology'' '''16''', 775-778.</ref><ref name="Perkins">Perkins, S. R., Beckett, T. A., Bump, C. M. (1986). [http://jcm.asm.org/content/24/4/675.abstract ''Cedecea davisae'' bacteremia.] ''Journal of Clinical Microbiology'' '''24''', 675-676.</ref><ref name="Dalamaga 2">Dalamaga, M., Karmaniolas, K., Arsenis, G., Pantelaki, M., Daskalopoulou, K., Papadavid, E., and Migdalis, I. (2008). [http://www.mendeley.com/research/cedecea-davisae-bacteremia/ ''Cedecea lapagei'' bacteremia following cement-related chemical burn injury.] ''Burns'' '''34''', 1205-1207.</ref>
==History of genus== ''Cedecea'' bacteria were discovered in 1977 by a group of scientists at the CDC and were initially named “Enteric Group 15”.<ref name="Grimont"/><ref name="Abate"/><ref name="Farmer"/><ref name="Dalamaga 2"/><ref name="Dalamaga">Dalamaga, M., and Vrioni, G. (2011). ''Cedecea''. ''Molecular detection of human bacterial pathogens'', 817-825.</ref> In 1980, Patrick A. D. Grimont and Francine Grimont proposed the genus name of ''Cedecea'' for this group.<ref name="Grimont"/><ref name="Abate"/><ref name="Farmer"/><ref name="Dalamaga 2"/><ref name="Dalamaga"/> This particular name was given to "Enteric Group 15" for the abbreviation of the Center for Disease Control (CDC) where the group of bacteria was discovered.<ref name="Grimont"/> At this time, six species have been identified.<ref name="Dalamaga"/> Currently, three strains have been named while three remain unnamed.<ref name="Grimont"/><ref name="Dalamaga"/>
''Cedecea davisae'' was named after Betty Davis. Davis is an American bacteriologist who has contributed to serological and biochemical identification of Enterobacteriaceae and Vibrionaceae.<ref name="Dalamaga"/>
''Cedecea lapagei'' was named after Stephen Lapage, who is a British bacteriologist. Lapage has contributed to bacterial systematics as the editor of ''Bacteriological Code''. Lapage has also made many contributions to the family Enterobacteriaceae.<ref name="Dalamaga"/>
''Cedecea neteri'' was named after Erwin Neter. Neter is an American microbiologist and physician. Like Davis and Lapage, Neter has contributed to the family Enterobacteriaceae.<ref name="Dalamaga"/>
==Clinical== ''Cedecea'' strains are rarely isolated from the environment or living human tissues.<ref name="Mawardi"/><ref name="Dalamaga 2"/> However, strains have, at one or more times, been isolated from the following human specimen: sputum, blood, skin wounds, gall bladder, urine and lung tissue.<ref name="Mawardi"/><ref name="Abate"/><ref name="Perkins"/><ref name="Dalamaga 2"/> These specimen were collected from a handful of patients who were elderly, medically compromised or immunocompromised.<ref name="Mawardi"/><ref name="Dalamaga 2"/> Even though these strains have been isolated, their role in disease and clinical significance is yet to be discovered.<ref name="Dalamaga 2"/>
==Treatment== Patients who are infected with ''Cedecea'' can benefit from antibiotic therapy; however, this can be a challenge due to ''Cedecea'' strains being resistant to a range of antimicrobial agents.<ref name="Mawardi"/><ref name="Abate"/><ref name="Dalamaga 2"/> ''Cedecea'' strains are resistant to the following antimicrobial agents: cephalothin, extended spectrum cephalosporins, colistin, and several aminoglycosides.<ref name="Dalamaga 2"/>
==Ecology== Several members of the ''Entereobacteriaceae'' live in the intestines of other organisms, and ''Cedecea'' have been isolated in wild tsetse flies and cockroaches.<ref>{{cite journal |author1=G.P. Kaaya |author2=Ma Okech | title= '' Microorganisms associated with Tsetse in nature'' | journal= Insect Science and Its Application | year=1990 |volume = 11|pages = 443–448 | doi=10.1017/s1742758400012868}}</ref><ref>{{cite journal | author=G. Pellegrini | title = Cockroaches, infestation and possible contribution in the spreading of some Enterobacteria | journal= Igiene Moderna | year=1990 | volume=97 | pages=19–30|display-authors=etal}}</ref> In humans, ''Cedecea'' has been located in the blood and saliva, wounds and abscesses, and in ulcerated tissue.<ref>{{cite journal |author1=S.R. Perkins |author2=T.A. Beckett |author3=C.M. Bump | title= ''Cedecea davisae bacteremia'' | journal= Journal of Clinical Microbiology | year=1986 | volume=24 |issue=4 | pages=675–676|doi=10.1128/jcm.24.4.675-676.1986 |pmid=3771758 |pmc=269000 }}</ref><ref>{{cite journal |author1=H. Mawardi |author2=M. Pavlakis |author3=D.S. Mandelbrot |author4=S.B. Woo | title=''Sirolimus oral ulcer with Cedecea davisae superinfection''| journal= Transpl Infectious Disease | year=2010 | volume=12 |issue=5 | pages=446–450 | doi=10.1111/j.1399-3062.2010.00514.x|pmid=20525018 }}</ref> The bacteria has been isolated and a limited amount of samples have been taken. Although resistant to several antibiotics, ''Cedecea'' - along with several other bacteria - has been shown to be subject to high antibacterial activity from ''Bovine lactoperoxidase''.<ref>{{cite journal |author1=M. Canyaka |author2=M. Sisecioglu |author3=O. Baris | title=Effects of bovine milk lactoperoxidase system on some bacteria | journal=Applied Biochemistry and Microbiology | year=2010 | volume=46 | pages= 64–68|display-authors=etal}}</ref>
==References== {{Reflist}}
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Category:Enterobacteriaceae Category:Bacteria genera