Calphostin C
Verifiedfieldschanged
Watchedfieldschanged
Verifiedrevid405921416
Iupacname[(2R)-1-[3,10-dihydroxy-12-[(2R)-2-(4-hydroxyphenoxy)carbonyloxypropyl]-2,6,7,11-tetramethoxy-4,9-dioxoperylen-1-yl]propan-2-yl] benzoate

Calphostin C is a natural chemical compound. It is one of the calphostins, isolated from the fungus Cladosporium cladosporioides.[1][2] Calphostin C is a potent inhibitor of protein kinase C (PKC).

References

  1. ^ Kobayashi, E; Ando, K; Nakano, H; Iida, T; Ohno, H; Morimoto, M; Tamaoki, T (1989). "Calphostins (UCN-1028), novel and specific inhibitors of protein kinase C. I. Fermentation, isolation, physico-chemical properties and biological activities". J. Antibiot.. 42 (10): 1470–1474. doi:10.7164/antibiotics.42.1470. PMID 2478514
  2. ^ Iida, T; Kobayashi, E; Yoshida, M; Sano, H (1989). "Calphostins, novel and specific inhibitors of protein kinase C. II. Chemical structures". J. Antibiot.. 42 (10): 1475–1481. doi:10.7164/antibiotics.42.1475. PMID 2478515