{{Short description|Protein produced by Helicobacter pylori bacteria}} {{Infobox protein family | Symbol = CagZ | Name = CagZ | image = PDB 1s2x EBI.jpg | width = | caption = crystal structure of cag-z from helicobacter pylori | Pfam = PF09053 | Pfam_clan = | InterPro = IPR015139 | SMART = | PROSITE = | MEROPS = | SCOP = | TCDB = | OPM family = | OPM protein = | CAZy = | CDD = }}
In molecular biology, '''CagZ''' is a protein produced by ''Helicobacter pylori'' (''Campylobacter pylori''). It is a 23 kDa protein consisting of a single compact L-shaped domain, composed of seven alpha-helices that run antiparallel to each other. 70% of the amino acids are in alpha-helix conformation and no beta-sheet is present. CagZ is essential for the translocation of the pathogenic protein CagA into host cells.<ref name="pmid15223328">{{cite journal |vauthors=Cendron L, Seydel A, Angelini A, Battistutta R, Zanotti G | title = Crystal structure of CagZ, a protein from the Helicobacter pylori pathogenicity island that encodes for a type IV secretion system | journal = J. Mol. Biol. | volume = 340 | issue = 4 | pages = 881–9 |date=July 2004 | pmid = 15223328 | doi = 10.1016/j.jmb.2004.05.016 }}</ref>
==References== {{reflist}} {{InterPro content|IPR015139}}
Category:Protein domains Category:Helicobacter pylori