Chromatin target of PRMT1

{{Short description|Protein found in humans}} {{Infobox_gene}} '''Chromatin target of PRMT1''' is a protein that in humans is encoded by the CHTOP gene.<ref name="entrez">{{cite web | title = Entrez Gene: Chromatin target of PRMT1 | url = https://www.ncbi.nlm.nih.gov/gene/26097 }}</ref>

== Function ==

This gene encodes a small nuclear protein that is characterized by an arginine and glycine rich region. The encoded protein may be involved in cell cycle progression. This protein interacts with protein arginine methyltransferases and plays a role in the activation of estradiol-dependent transcription. Alternate splicing results in multiple transcript variants.

== References == {{reflist}}

== Further reading == {{refbegin | 2}} * {{cite journal | vauthors = Zullo AJ, Michaud M, Zhang W, Grusby MJ | title = Identification of the small protein rich in arginine and glycine (SRAG): a newly identified nucleolar protein that can regulate cell proliferation | journal = The Journal of Biological Chemistry | volume = 284 | issue = 18 | pages = 12504–11 | date = May 2009 | pmid = 19254951 | pmc = 2673316 | doi = 10.1074/jbc.M809436200 | doi-access = free }} * {{cite journal | vauthors = Chang CT, Hautbergue GM, Walsh MJ, Viphakone N, van Dijk TB, Philipsen S, Wilson SA | title = Chtop is a component of the dynamic TREX mRNA export complex | journal = The EMBO Journal | volume = 32 | issue = 3 | pages = 473–86 | date = February 2013 | pmid = 23299939 | pmc = 3567497 | doi = 10.1038/emboj.2012.342 }} * {{cite journal | vauthors = Teng IF, Wilson SA | title = Mapping interactions between mRNA export factors in living cells | journal = PLOS ONE | volume = 8 | issue = 6 | article-number = e67676 | year = 2013 | pmid = 23826332 | pmc = 3691119 | doi = 10.1371/journal.pone.0067676 | bibcode = 2013PLoSO...867676T | doi-access = free }} * {{cite journal | vauthors = van Dijk TB, Gillemans N, Stein C, Fanis P, Demmers J, van de Corput M, Essers J, Grosveld F, Bauer UM, Philipsen S | title = Friend of Prmt1, a novel chromatin target of protein arginine methyltransferases | journal = Molecular and Cellular Biology | volume = 30 | issue = 1 | pages = 260–72 | date = January 2010 | pmid = 19858291 | pmc = 2798285 | doi = 10.1128/MCB.00645-09 }} * {{cite journal | vauthors = van Dijk TB, Gillemans N, Pourfarzad F, van Lom K, von Lindern M, Grosveld F, Philipsen S | title = Fetal globin expression is regulated by Friend of Prmt1 | journal = Blood | volume = 116 | issue = 20 | pages = 4349–52 | date = November 2010 | pmid = 20688955 | pmc = 2993632 | doi = 10.1182/blood-2010-03-274399 }} {{refend}}