CHTF18

{{Short description|Protein-coding gene in humans}} {{Infobox_gene}} '''Chromosome transmission fidelity protein 18 homolog''' is a protein that in humans is encoded by the ''CHTF18'' gene.<ref name="pmid12171929">{{cite journal | vauthors = Ohta S, Shiomi Y, Sugimoto K, Obuse C, Tsurimoto T | title = A proteomics approach to identify proliferating cell nuclear antigen (PCNA)-binding proteins in human cell lysates. Identification of the human CHL12/RFCs2-5 complex as a novel PCNA-binding protein | journal = The Journal of Biological Chemistry | volume = 277 | issue = 43 | pages = 40362–7 | date = Oct 2002 | pmid = 12171929 | doi = 10.1074/jbc.M206194200 | doi-access = free }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: CHTF18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)| url = https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=63922}}</ref>

== Interactions ==

CHTF18 has been shown to interact with: * DCC1,<ref name = pmid12930902>{{cite journal | vauthors = Bermudez VP, Maniwa Y, Tappin I, Ozato K, Yokomori K, Hurwitz J | title = The alternative Ctf18-Dcc1-Ctf8-replication factor C complex required for sister chromatid cohesion loads proliferating cell nuclear antigen onto DNA | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 100 | issue = 18 | pages = 10237–42 | date = Sep 2003 | pmid = 12930902 | pmc = 193545 | doi = 10.1073/pnas.1434308100 | bibcode = 2003PNAS..10010237B | doi-access = free }}</ref><ref name = pmid12766176>{{cite journal | vauthors = Merkle CJ, Karnitz LM, Henry-Sánchez JT, Chen J | title = Cloning and characterization of hCTF18, hCTF8, and hDCC1. Human homologs of a Saccharomyces cerevisiae complex involved in sister chromatid cohesion establishment | journal = The Journal of Biological Chemistry | volume = 278 | issue = 32 | pages = 30051–6 | date = Aug 2003 | pmid = 12766176 | doi = 10.1074/jbc.M211591200 | doi-access = free }}</ref> * PCNA,<ref name = pmid12171929 /> * RFC2,<ref name = pmid12930902/><ref name = pmid12766176/> * RFC3,<ref name = pmid12930902/><ref name = pmid12766176/> * RFC4,<ref name = pmid12930902/> and * RFC5.<ref name = pmid12930902/>

== References == {{reflist}}

==External links== * {{UCSC gene info|CHTF18}}

== Further reading == {{refbegin | 2}} * {{cite journal | vauthors = Shiomi Y, Masutani C, Hanaoka F, Kimura H, Tsurimoto T | title = A second proliferating cell nuclear antigen loader complex, Ctf18-replication factor C, stimulates DNA polymerase eta activity | journal = The Journal of Biological Chemistry | volume = 282 | issue = 29 | pages = 20906–14 | date = Jul 2007 | pmid = 17545166 | doi = 10.1074/jbc.M610102200 | doi-access = free }} * {{cite journal | vauthors = Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP | title = Large-scale characterization of HeLa cell nuclear phosphoproteins | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 101 | issue = 33 | pages = 12130–5 | date = Aug 2004 | pmid = 15302935 | pmc = 514446 | doi = 10.1073/pnas.0404720101 | bibcode = 2004PNAS..10112130B | doi-access = free }} * {{cite journal | vauthors = Bermudez VP, Maniwa Y, Tappin I, Ozato K, Yokomori K, Hurwitz J | title = The alternative Ctf18-Dcc1-Ctf8-replication factor C complex required for sister chromatid cohesion loads proliferating cell nuclear antigen onto DNA | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 100 | issue = 18 | pages = 10237–42 | date = Sep 2003 | pmid = 12930902 | pmc = 193545 | doi = 10.1073/pnas.1434308100 | bibcode = 2003PNAS..10010237B | doi-access = free }} * {{cite journal | vauthors = Merkle CJ, Karnitz LM, Henry-Sánchez JT, Chen J | title = Cloning and characterization of hCTF18, hCTF8, and hDCC1. Human homologs of a Saccharomyces cerevisiae complex involved in sister chromatid cohesion establishment | journal = The Journal of Biological Chemistry | volume = 278 | issue = 32 | pages = 30051–6 | date = Aug 2003 | pmid = 12766176 | doi = 10.1074/jbc.M211591200 | doi-access = free }} * {{cite journal | vauthors = Naiki T, Kondo T, Nakada D, Matsumoto K, Sugimoto K | title = Chl12 (Ctf18) forms a novel replication factor C-related complex and functions redundantly with Rad24 in the DNA replication checkpoint pathway | journal = Molecular and Cellular Biology | volume = 21 | issue = 17 | pages = 5838–45 | date = Sep 2001 | pmid = 11486023 | pmc = 87303 | doi = 10.1128/MCB.21.17.5838-5845.2001 }} * {{cite journal | vauthors = Daniels RJ, Peden JF, Lloyd C, Horsley SW, Clark K, Tufarelli C, Kearney L, Buckle VJ, Doggett NA, Flint J, Higgs DR | title = Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16 | journal = Human Molecular Genetics | volume = 10 | issue = 4 | pages = 339–52 | date = Feb 2001 | pmid = 11157797 | doi = 10.1093/hmg/10.4.339 | doi-access = free }} {{refend}}