{{Short description|Biological database}} {{Infobox biodatabase|title=CBMAR|logo=|description=Beta-lactamase database annotating beta-lactamase based on their characteristics|scope=Beta-lactamase|organism=Bacteria|center=|laboratory=|author=|pmid=25475113|released=|standard=|format=|url={{URL|http://14.139.227.92/mkumar/lactamasedb}}|download=|webservice=|sql=|sparql=|webapp=|standalone=|license=|versioning=|frequency=|curation=|bookmark=yes|version=}}'''CBMAR''' ('''Comprehensive β-lactamase Molecular Annotation Resource''') is a database focused on the annotation and discovery of novel beta-lactamase genes and proteins in bacteria.<ref>{{Cite journal|last1=Srivastava|first1=Abhishikha|last2=Singhal|first2=Neelja|last3=Goel|first3=Manisha|last4=Virdi|first4=Jugsharan Singh|last5=Kumar|first5=Manish|date=2014-01-01|title=CBMAR: a comprehensive β-lactamase molecular annotation resource|journal=Database|language=en|volume=2014|article-number=bau111|doi=10.1093/database/bau111|pmid=25475113|issn=1758-0463|pmc=4255060}}</ref> Beta-lactamases are characterized on CBMAR using the Ambler Classification system.<ref>{{Cite journal|last=Ambler|first=R. P.|date=1980-05-16|title=The Structure of <latex>$\beta$</latex>-Lactamases|journal=Philosophical Transactions of the Royal Society B: Biological Sciences|volume=289|issue=1036|pages=321–331|doi=10.1098/rstb.1980.0049|pmid=6109327|issn=0962-8436|doi-access=}}</ref> CBMAR organizes beta-lactamases according to their classes: A, B, C, and D. They are then further categorized by their (i) sequence variability, (ii) antibiotic resistance profile, (iii) inhibitor susceptibility, (iv) active site, (v) family fingerprints, (vi) mutational profile, (vii) variants, (viii) gene location, (ix) phylogenetic tree, etc. The primary sources of database for CBMAR are GenBank and Uniprot.<ref>{{Cite journal|date=2011-11-18|title=Reorganizing the protein space at the Universal Protein Resource (UniProt)|journal=Nucleic Acids Research|volume=40|issue=D1|pages=D71–D75|doi=10.1093/nar/gkr981|pmid=22102590|issn=0305-1048|pmc=3245120|author1=The UniProt Consortium}}</ref> CBMAR is built on an Apache HTTP Server 2.2.17 with MySQL Ver 14.14 and hosted on Ubuntu 11.04 Linux platform.
== See also == * Antimicrobial Resistance databases
== References == {{reflist}}
Category:Antimicrobial resistance organizations Category:Beta-lactam antibiotics Category:Enzyme databases
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