CA10 — Mediated Wiki

{{Short description|Protein-coding gene in humans}} {{About||the [[United States courts of appeals|U.S. federal circuit court of appeals]]|United States Court of Appeals for the Tenth Circuit|the highway|California State Route 10 (disambiguation){{!}}California State Route 10|the congressional district|California's 10th congressional district}}

{{Infobox_gene}} '''Carbonic anhydrase-related protein 10''' is an [[enzyme]] that in humans is encoded by the ''CA10'' [[gene]].<ref name="pmid8673298">{{cite journal | vauthors = Hewett-Emmett D, Tashian RE | title = Functional diversity, conservation, and convergence in the evolution of the alpha-, beta-, and gamma-carbonic anhydrase gene families | journal = Mol Phylogenet Evol | volume = 5 | issue = 1 | pages = 50–77 |date=Aug 1996 | pmid = 8673298 | doi = 10.1006/mpev.1996.0006 }}</ref><ref name="pmid9921901">{{cite journal | vauthors = Kleiderlein JJ, Nisson PE, Jessee J, Li WB, Becker KG, Derby ML, Ross CA, Margolis RL | title = CCG repeats in cDNAs from human brain | journal = Hum Genet | volume = 103 | issue = 6 | pages = 666–73 |date=Feb 1999 | pmid = 9921901 | doi =10.1007/s004390050889 | s2cid = 23696667 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: CA10 carbonic anhydrase X| url = https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=56934}}</ref>

This gene encodes a [[protein]] that belongs to the [[carbonic anhydrase]] family of [[zinc]] [[metalloenzymes]], which catalyze the reversible hydration of [[carbon dioxide]] in various biological processes. The protein encoded by this gene is an acatalytic member of the alpha-carbonic anhydrase subgroup, and it is thought to play a role in the [[central nervous system]], especially in [[brain development]]. Multiple [[transcript variants]] encoding the same protein have been found for this gene.<ref name="entrez"/>

==References== {{reflist}}

==External links== * {{UCSC gene info|CA10}}

==Further reading== {{refbegin | 2}} *{{cite journal | vauthors=Supuran CT, Scozzafava A, Casini A |title=Carbonic anhydrase inhibitors. |journal=Med Res Rev |volume=23 |issue= 2 |pages= 146–89 |year= 2003 |pmid= 12500287 |doi= 10.1002/med.10025 |s2cid=90349277 |doi-access=free }} *{{cite journal | vauthors=Supuran CT, Vullo D, Manole G |title=Designing of novel carbonic anhydrase inhibitors and activators. |journal=Curr Med Chem Cardiovasc Hematol Agents |volume=2 |issue= 1 |pages= 49–68 |year= 2005 |pmid= 15328829 |doi=10.2174/1568016043477305 |display-authors=etal}} *{{cite journal | vauthors=Pastorekova S, Parkkila S, Pastorek J, Supuran CT |title=Carbonic anhydrases: current state of the art, therapeutic applications and future prospects. |journal=J Enzyme Inhib Med Chem |volume=19 |issue= 3 |pages= 199–229 |year= 2004 |pmid= 15499993 |doi=10.1080/14756360410001689540 |s2cid=218868129 }} *{{cite journal | vauthors=Wiemann S, Weil B, Wellenreuther R |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422–35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.GR1547R | pmc=311072 |display-authors=etal}} *{{cite journal | vauthors=Okamoto N, Fujikawa-Adachi K, Nishimori I |title=cDNA sequence of human carbonic anhydrase-related protein, CA-RP X: mRNA expressions of CA-RP X and XI in human brain. |journal=Biochim. Biophys. Acta |volume=1518 |issue= 3 |pages= 311–6 |year= 2001 |pmid= 11311946 |doi= 10.1016/s0167-4781(01)00193-2|display-authors=etal}} *{{cite journal | vauthors=Taniuchi K, Nishimori I, Takeuchi T |title=Developmental expression of carbonic anhydrase-related proteins VIII, X, and XI in the human brain. |journal=Neuroscience |volume=112 |issue= 1 |pages= 93–9 |year= 2002 |pmid= 12044474 |doi=10.1016/S0306-4522(02)00066-0 |s2cid=31186391 |display-authors=etal}} *{{cite journal | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |display-authors=etal|doi-access=free }} *{{cite journal | vauthors=Clark HF, Gurney AL, Abaya E |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003 | pmc=403697 |display-authors=etal}} *{{cite journal | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}} *{{cite journal | vauthors=Kimura K, Wakamatsu A, Suzuki Y |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 | pmc=1356129 |display-authors=etal}} *{{cite journal | vauthors=Olsen JV, Blagoev B, Gnad F |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 |s2cid=7827573 |display-authors=etal|doi-access=free }} {{refend}}