Prior to Ottawa's amalgamation in 2001, the ward covered the entire former city of Vanier as well as Ottawa's Bruyère-Strathcona Ward on regional council. Bruyère-Strathcona was created in 1994 from parts of By-Rideau Ward and St. George's Ward and was initially named Ward 5 until 1995 when it was given the Bruyère-Strathcona name.
By-St. George's Ward covered this area (not including Vanier, which was a separate city) from 1972 to 1980. By-St. George's was created from the merging of By Ward and St. George's Ward, and was abolished when it was split into St. George's Ward and By-Rideau Ward in 1980.