Brandon Colby

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'''Brandon Ross Colby''' is an American physician in Beverly Hills, California<ref name=DCA>{{cite web |url=https://search.dca.ca.gov/details/8002/A/92750/105fd2e896b553d2d2ccf357bb58da23 |title=Licensing details for: A 92750 |last= |first= |date= |website=California Department of Consumer Affairs |publisher= |access-date=July 16, 2024 |quote=}}</ref> and physician specializing in predictive medicine and genetic testing. He is author of ''Outsmart Your Genes'', a book about genetics published in 2011, and he is the founder and CEO of direct-to-consumer genetic testing service Sequencing.<ref>{{cite web | last=Rabbitt | first=Meghan | title=Tips to Outsmart Genetic Health Risks | website=Prevention | date=February 24, 2021 | url=https://www.prevention.com/health/a35369807/genetics-and-health/ | access-date=July 17, 2024}}</ref>

== Early life and education == Colby was born with epidermolysis bullosa simplex (EB), a rare genetic disease that causes heat-sensitivity of the skin, leading to blisters on the hands and feet when skin temperature rises. Because of his condition he had an interest in genetics early in life.

Colby holds a degree in genetics from the University of Michigan, a 2004 Medical Doctorate from Mount Sinai School of Medicine,<ref name=DCA/> and a 2007 Master of Business Administration from Stanford University's Graduate School of Business.<ref name="Stanford">{{cite web |author-first=Dana |author-last=Mauriello | title=Brandon Colby, MBA '07: Charting the Course for a Predictive Medicine Venture | website=Stanford Graduate School of Business | date=November 2, 2017 | url=https://www.gsb.stanford.edu/experience/news-history/brandon-colby-mba-07-charting-course-predictive-medicine-venture | access-date=July 17, 2024}}</ref><ref>{{Cite web |title=Outsmart Your Genes {{!}} Dr. Brandon Colby MD |url=https://sequencing.com/education-center/outsmart-your-genes |access-date=2023-02-26 |website=Sequencing.com |language=en}}</ref>

== Career ==

Colby founded Existence Genetics in 2005 during his second year at Stanford.<ref name="Stanford"/> The business declared bankruptcy on November 21, 2012. Existence Genetics was a genetic analysis and genetic reporting company that provided the healthcare industry and health & wellness organizations with information about their clients' genes.<ref>{{cite web|author=Steve Parker |url=http://www.genomeweb.com/dxpgx/existence-genetics-ramps-widespread-test-service-launch-eyes-whole-genome-sequen |title=Existence Genetics Ramps up for Widespread Test Service Launch, Eyes Whole-Genome Sequencing |publisher=GenomeWeb |date= 8 October 2010|access-date=2011-06-01}}</ref>

Colby was also medical director of Existence Health, a medical practice founded in 2010 and based in Los Angeles that provided predictive medicine services to its patients based upon a person's genes.

=== Sequencing ===

Colby founded Sequencing (sequencing.com), which launched in September 2016. It hosts genomic sequencing data for individuals and for researchers, an API through which third parties can interface with the data, and an app store. The app store allows purchase of further genetic data interpretation, such as results for Alzheimer's disease.<ref>{{cite web | last=Richards| first=Sarah Elizabeth| title=Now You Can Genetically Test Your Child For Disease Risks. Should You? | website=Smithsonian Magazine | date=February 5, 2018 | url=https://www.smithsonianmag.com/science-nature/now-you-can-genetically-test-your-child-should-you-180968012/ | access-date=July 17, 2024}}</ref> Genomics Personalized Health provides genomic sequencing, EncrypGen provides secure data transfer with blockchain, and Sequencing hosts genomic data and offers interpretation of results.<ref> {{cite web |url=https://news.marketersmedia.com/encrypgen-inc-add-new-alliances-sequencing-com-genomics-personalized-health/293670 |title=EncrypGen, Inc. Add New Alliances: Sequencing.com & Genomics Personalized Health |last= |first= |date=January 29, 2018 |website=Marketers Media |publisher= |access-date=July 18, 2024 |type=Press release}}</ref><ref>DNA Can Guide the Way: Genome Mapping Offers Look Into Medical Future. ''Corpus Christi Caller - Times'', July 07, 2016. https://www.proquest.com/newspapers/dna-can-guide-way/docview/2581329790/se-2 (accessed July 19, 2024).</ref><ref>{{cite web | title=Sequencing.com launches genetic data platform | website=ProQuest | url=https://www.proquest.com/docview/1847407330 | ref={{sfnref | ProQuest}} | access-date=2024-07-19| id={{ProQuest|1847407330}} }}</ref> A patent assigned to sequencing.com was filed in 2014.<ref>{{cite web |url=https://go.gale.com/ps/retrieve.do?tabID=T002&resultListType=RESULT_LIST&searchResultsType=SingleTab&retrievalId=60a35c59-c25a-466b-ad73-5bb90ecea9e5&hitCount=5&searchType=AdvancedSearchForm&currentPosition=4&docId=GALE%7CA470796058&docType=Article&sort=Relevance&contentSegment=ZONE-Exclude-FT&prodId=AONE&pageNum=1&contentSet=GALE%7CA470796058&searchId=R4&userGroupName=wikipedia&inPS=true |title=Researchers Submit Patent Application, "System and Method for Real-Time Personalization Utilizing an Individual'S Genomic Data", for Approval (USPTO 20160321395) |last= |first= |date=November 26, 2016 |website=Gale Academic OneFile |publisher=NewsRX |access-date=July 18, 2024 |quote=}}</ref><ref>{{cite journal | last1=Guerrini | first1=Christi J. | last2=Lewellyn | first2=Meaganne | last3=Majumder | first3=Mary A. | last4=Trejo | first4=Meredith | last5=Canfield | first5=Isabel | last6=McGuire | first6=Amy L. | title=Donors, authors, and owners: how is genomic citizen science addressing interests in research outputs? | journal=BMC Medical Ethics | volume=20 | issue=1 | date=2019 | page=84 | issn=1472-6939 | pmid=31752834 | pmc=6868686 | doi=10.1186/s12910-019-0419-1 | doi-access=free}}</ref>

In 2022, Sequencing raised five million dollars in a round of venture capital financing.<ref>{{cite web |url=https://vcnewsdaily.com/sequencing.com/venture-capital-funding/scdxdlnzns |title=Sequencing.com Raises $5M In Venture Capital |last= |first= |date=November 9, 2022 |website=VC News Daily |publisher=Massinvestor |access-date=July 18, 2024 |quote=}}</ref><ref>"VC Health Pulse: Expected Gridlock in Washington Shifts Healthcare VCs' Attention to States; Biotech Startup Juvena Therapeutics Grabs $41 Million." Dow Jones Institutional News, November 10, 2022, https://www.proquest.com/wire-feeds/vc-health-pulse-expected-gridlock-washington/docview/2734893339/se-2 (accessed July 19, 2024).</ref> Sequencing has been profiled as a "key company" in ResearchandMarkets.com's whole genome and exome market research reports since 2021.<ref>{{cite web |url=https://www.prnewswire.com/news-releases/whole-genome-and-exome-sequencing-market-analysis-2023-2024-and-2027-with-executive-and-consultant-guides-featuring-llumina-ion-pacific-biosystems-roche-solid-oxford-nanopore-among-others-302101528.html |title=Whole Genome and Exome Sequencing Market Analysis 2023-2024 and 2027 with Executive and Consultant Guides Featuring llumina, ION, Pacific Biosystems, Roche, SOLiD, Oxford Nanopore Among Others |last= |first= |date=March 28, 2024 |website=PR Newswire |publisher= |access-date=July 18, 2024 |type=Press release}}</ref><ref>{{cite web |url=https://www.businesswire.com/news/home/20211005005851/en/Whole-Genome-And-Exome-Sequencing-Markets-Q4-2021-Market-Report---ResearchAndMarkets.com |title=Whole Genome And Exome Sequencing Markets, Q4 2021 Market Report - ResearchAndMarkets.com |last= |first= |date=October 5, 2021 |website=Business Wire |publisher= |access-date=July 18, 2024 |type=Press release}}</ref>

== Publications ==

Colby co-authored "Congenital erythropoietic porphyria: identification and expression of eight novel mutations in the uroporphyrinogen III synthase gene", which appeared in British Journal of Haematology in 2002. In 2010, Penguin Random House published Colby's ''Outsmart Your Genes'' ({{ISBN|9780399536380}}), a book about genetic testing and predictive medicine.<ref>{{cite journal | last1=Shady | first1=Amr A. | last2=Colby | first2=Brandon R. | last3=Cunha | first3=Luis F. | last4=Astrin | first4=Kenneth H. | last5=Bishop | first5=David F. | last6=Desnick | first6=Robert J. | title=Congenital erythropoietic porphyria: identification and expression of eight novel mutations in the uroporphyrinogen III synthase gene | journal=British Journal of Haematology | volume=117 | issue=4 | date=2002 | issn=0007-1048 | doi=10.1046/j.1365-2141.2002.03558.x | pages=980–987| pmid=12060141 }}</ref><ref>Brendan Colby. Outsmart Your Genes: How Understanding Your DNA Will Empower You to Protect Yourself Against Cancer, Alzheimer's, Heart Disease, Obesity, and Many Other Conditions. Penguin, 2010. {{ISBN|0399535578}}</ref><ref>Andrea Hoffmann and Panagiotis A Tsonis. [http://www.humgenomics.com/content/5/5/516 Book Review: Outsmart Your Genes] Human Genomics 2011, 5:516-517</ref>

== Media appearances ==

In April 2011, Colby appeared on the "How to Outsmart Your Genes" episode of the TV show ''The Doctors''. Existence Genetics performed genetic testing on several of the show's guests and Colby discussed the results. The testing focused on male pattern baldness, sexual compatibility, preconception, and disease predisposition.<ref>{{cite web |url=http://www.thedoctorstv.com/main/show_synopsis/741?section=synopsis |archive-url=https://web.archive.org/web/20110426061944/http://www.thedoctorstv.com/main/show_synopsis/741?section=synopsis |url-status=dead |archive-date=2011-04-26 |title=Show Synopsis |publisher=Thedoctorstv.com |date= |access-date=2011-06-01 }}</ref>

Colby has also appeared on ABC's ''Good Morning America'' in April, 2010, and the Today Show with Megyn Kelly in 2018.<ref>Kelly, Megyn. A look at the story of Taylor Muhl. Today (Feb 23, 2018), https://www.proquest.com/other-sources/look-at-story-taylor-muhl/docview/2008176519/se-2 (accessed July 19, 2024).</ref>

== References ==

== Further reading ==

* {{cite news|last1=Ashford|first1=Molika|title=Sequencing.com Hopes to Shepherd Growing Market of DIY Genomics Tools|url=https://www.genomeweb.com/sequencing/sequencingcom-hopes-shepherd-growing-market-diy-genomics-tools|date=27 September 2016}} * {{cite web |url=https://www.the-scientist.com/what-your-dna-cant-tell-you-66523 |title=What Your DNA Can't Tell You |last=Kwon |first=Diana |date=October 2, 2019 |website=The Scientist |publisher=LabX Media Group |access-date= |quote= |url-access=registration}} * {{cite web |url=https://www.healthcare-brew.com/stories/2023/07/24/direct-to-consumer-genome-sequencing-could-be-key-to-the-future-of-healthcare |title=Direct-to-consumer genome sequencing could be key to the future of healthcare |last=Young |first=Shannon |date=July 24, 2023 |website=Healthcare Brew |publisher=Morning Brew, Inc |access-date= |quote=}}

== External links ==

* [https://sequencing.com/ Sequencing.com] * [https://www.outsmartyourgenes.com/index.php Outsmart Your Genes official website] * [https://www.penguinrandomhouse.com/books/304995/outsmart-your-genes-by-brandon-colby/ Outsmart Your Genes] at Penguin Random House * Preview {{Google books|id=CP6IH8CmO6kC|title=Outsmart Your Genes: How Understanding Your DNA Will Empower You to Protect Yourself Against Cancer, Alzheimer's, Heart Disease, Obesity, and Many Other Conditions}} * Preview [https://archive.org/details/outsmartyourgene0000colb_x0h0 ''Outsmart Your Genes''] at Internet Archive

{{DEFAULTSORT:Colby, Brandon}} Category:American chief executives in the health care industry Category:American geneticists Category:American businesspeople in the pharmaceutical industry Category:American businesspeople in the health care industry Category:American medical writers Category:American male non-fiction writers Category:American medical researchers Category:University of Michigan alumni Category:Living people Category:Year of birth missing (living people) Category:Stanford Graduate School of Business alumni Category:Icahn School of Medicine at Mount Sinai alumni

Brandon Colby

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