{{Short description|none}} :''This is an [[Wikipedia:WikiProject Lists#Incomplete lists|incomplete list]], which may never be able to satisfy certain standards for completion.''
There are many conditions of or affecting the human [[Circulatory system|hematologic system]]—the [[biological system]] that includes [[Blood plasma|plasma]], [[platelet]]s, [[leukocyte]]s, and [[erythrocyte]]s, the major components of blood and the [[bone marrow]].<ref name="Saladin">{{cite book|last=Saladin|first=Kenneth S.|author2=Miller, Leslie |title=Anatomy & Physiology: The Unity of form and Function|publisher=McGraw-Hill|year=2004|edition=3rd|pages=679|chapter=18|isbn=0-07-242903-8}}</ref>
==Anemias== [[Image:Anemia.JPG|thumb|200px|right|The pale hand of a woman with severe anemia (left) in comparison to the normal hand of her husband (right)]] {{Main|Anemia}}
An [[anemia]] is a decrease in number of [[red blood cell]]s (RBCs) or less than the normal quantity of [[hemoglobin]] in the blood.<ref name=medterms>[http://www.medterms.com/script/main/art.asp?articlekey=15491 MedicineNet.com Definition of Anemia] Last Editorial Review: 12/9/2000 Retrieved March 27, 2011</ref><ref name=merriam>[http://www.merriam-webster.com/dictionary/anemia ''Merriam-Webster Dictionary'' anemia] Retrieved on March 27, 2011</ref> However, it can include decreased oxygen-binding ability of each hemoglobin molecule due to deformity or lack in numerical development as in some other types of [[hemoglobin deficiency]].{{citation needed|date=July 2022}}
Anemia is the most common disorder of the blood. There are several kinds of anemia, produced by a variety of underlying causes. Anemia can be classified in a variety of ways, based on the morphology of RBCs, underlying etiologic mechanisms, and discernible clinical spectra, to mention a few. The three main classes of anemia include excessive blood loss (acutely such as a [[hemorrhage]] or chronically through low-volume loss), excessive blood cell destruction ([[hemolysis]]) or deficient red blood cell production (ineffective [[hematopoiesis]]). Based on 2005-2006 estimates, the [[Centers for Disease Control and Prevention]] has stated that approximately 5.5 million Americans a year are either admitted to a hospital or seen by a physician, with some form of anemia as their primary diagnosis.<ref>{{cite web|url=https://www.cdc.gov/nchs/fastats/anemia.htm|title=Anemia or Iron Deficiency|date=15 April 2010|publisher=Centers for Disease Control and Prevention|accessdate=28 March 2011}}</ref>
Symptoms of anaemia include Plummer–Vinson syndrome, candidal infections. Altered taste sensation, smooth, red painful burning sensation of tongue, filiform followed by fungiform papillae atrophy may also be seen. Others include generalized stomatitis, angular cheilitis and gingivitis.{{citation needed|date=July 2022}}
Oral manifestation of anemia include angular cheilitis, generalized stomatitis, candidiasis and gingivitis. There will be pallor of lips and oral mucosa. Patients might have a smooth, red painful tongue, experience burning sensation of tongue or disturbed taste sensation. Atrophy of filiform and fungiform papillae may also occur.{{citation needed|date=July 2022}}
===Nutritional anemias=== A nutritional anemia is a type of anemia that can be directly attributed to either a nutritional disorder or a nutritional deficiency. {| class="wikitable" style="width:100%; margin-right:auto; background: #FFFFFF;" |- style="color:white" !style="background-color:#6699CC; width:55%"| Condition name !style="background-color:#6699CC; width:25%"| ICD-10 coding number !style="background-color:#6699CC; width:10%"| Diseases Database coding number !style="background-color:#6699CC; width:10%"| Medical Subject Headings |- |[[Iron-deficiency anemia]] || {{ICD10|D|50||d|50}} || {{DiseasesDB|6947||none}} || |- |colspan="6"| Iron-deficiency anemia (or iron deficiency anaemia) is a common anemia that occurs when iron loss (often from intestinal bleeding or menses) occurs, and/or the dietary intake or absorption of [[iron]] is insufficient. In such a state, hemoglobin, which contains iron, cannot be formed.<ref>{{cite journal |author=Brady PG |title=Iron deficiency anemia: a call for |journal=South. Med. J. |volume=100 |issue=10 |pages=966–7 |year=2007 |pmid=17943034 |doi=10.1097/SMJ.0b013e3181520699 }}</ref> |- |colspan="6" bgcolor="#6699CC"| |- | [[Plummer–Vinson syndrome]] || {{ICD10|D|50|1|d|50}} || {{DiseasesDB|10134||none}} || |- |colspan="6"| Plummer–Vinson syndrome (PVS), also called Paterson–Brown–Kelly syndrome or sideropenic dysphagia presents as a triad of [[dysphagia]] (due to [[esophageal webs]]), [[glossitis]], and [[iron-deficiency anemia]].<ref name="pmid16978405">{{cite journal |author=Novacek G |title=Plummer-Vinson syndrome |journal=Orphanet J Rare Dis |volume=1 |pages=36 |year=2006 |pmid=16978405 |doi=10.1186/1750-1172-1-36 |pmc=1586011 |doi-access=free }}</ref> It most usually occurs in [[postmenopausal]] women. |- |colspan="6" bgcolor="#6699CC"| |- |[[Vitamin B12 deficiency anemia]] ||{{ICD10|E|53|8|e|50}} || {{DiseasesDB|13905||none}} || |- |colspan="6"| Vitamin B12 deficiency anemia occurs when a "lower-than-normal" amount of the vitamin B12 is available within the body, leading to a decreased production of healthy red blood cells.<ref>{{cite web|url=http://www.mayoclinic.com/health/vitamin-deficiency-anemia/DS00325|title=Vitamin deficiency anemia|last=Mayo Clinic staff|date=March 4, 2011|work=Mayo Foundation for Medical Education and Research|publisher=Mayo Clinic|accessdate=5 March 2011}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- | [[Vitamin B12 deficiency|Vitamin B12 deficiency anemia due to intrinsic factor deficiency]] || {{ICD10|D|51|0|d|50}} || || |- |colspan="6"| Vitamin B12 deficiency is caused by a lack of intrinsic factor, as seen in pernicious anemia, causes a vitamin B12 deficiency. |- |colspan="6" bgcolor="#6699CC"| |- |[[Pernicious anemia]] || {{ICD10|D|51|0|d|50}}|| {{DiseasesDB|9870||none}} || |- |colspan="6"| Pernicious anemia (also known as macrocytic achylic anemia, congenital pernicious anemia, juvenile pernicious anemia, and Vitamin B12 deficiency) is one of many types of the larger family of [[megaloblastic anemia]]s. It is caused by loss of gastric parietal cells, and subsequent inability to absorb vitamin B<sub>12</sub>. Pernicious anemia is the result of inadequate production of the protein [[intrinsic factor]] needed by the body to absorb vitamin B <sub>12</sub>, causing a reduction of new red blood cells.<ref>{{cite web|url=https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001595/|archive-url=https://web.archive.org/web/20110206172320/http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001595|url-status=dead|archive-date=February 6, 2011|title=Pernicious anemia|date=November 23, 2008|work=National Center for Biotechnology Information (NCBI)|publisher=U.S. National Library of Medicine|accessdate=1 March 2011}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Vitamin B12|Vitamin B 12 deficiency anemia due to selective vitamin B 12 malabsorption with proteinuria]] || || || |- |colspan="6"| Vitamin B 12 deficiency anemia due to selective vitamin B 12 malabsorption with proteinuria (also known as Imerslund-Gräsbeck syndrome) is a rare autosomal recessive disorder which requires the indefinite administration of Vitamin B12 injections.<ref>{{cite journal|pmid=16722557|title=Imerslund-Gräsbeck syndrome (selective vitamin B(12) malabsorption with proteinuria)|last=Gräsbeck|first=R.|date=May 19, 2006|doi=10.1186/1750-1172-1-17|pmc=1513194|volume=1|journal=Orphanet J Rare Dis|pages=17 |doi-access=free }}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Megaloblastic anemia|Megaloblastic hereditary anemia]] || {{ICD10|D|51|1|d|50}}, {{ICD10|D|52|0|d|50}}, {{ICD10|D|53|1|d|50}} || {{DiseasesDB|29507||none}} || |- |colspan="6"| Megaloblastic anemia (or megaloblastic anaemia) is an anemia (of [[macrocytic anemia|macrocytic]] classification) that results from inhibition of [[DNA synthesis]] in red blood cell production.<ref name="urlMegaloblastic Anemia: Overview - eMedicine Hematology">{{cite web |url=http://emedicine.medscape.com/article/204066-overview |title=Megaloblastic Anemia: Overview - eMedicine Hematology |accessdate=2009-02-07}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Transcobalamin II|Transcobalamin II deficiency]] ||{{ICD10|D|51|2|d|50}} || || |- |colspan="6"| Transcobalamin II deficiency (TCII) (also known as hereditary transcobalamin II deficiency) is a rare [[autosomal recessive]] disorder that results in neurological dysfunction.<ref>{{cite journal|title=Transcobalamin II deficiency: Case report and review of the literature|volume=150|issue=12|last=Kaikov|first=Y.|author2=L. D. Wadsworth, C. A. Hall and P. C. J. Rogers|year=1991|journal=European Journal of Pediatrics|pages=Volume 150, Number 12, 841–843 |doi= 10.1007/BF01955004|pmid=1743216|last3=Hall|first3=C. A.|last4=Rogers|first4=P. C. J.|s2cid=11707936}}</ref> Transcobalamin II are a type of [[carrier protein]]s which bind with plasma vitamin B12 ([[cobalamin]]) in the production of red blood cells.<ref>{{cite journal|pmc=301974|title=Transcobalamins I and II as natural transport proteins of vitamin B12.|last=Hall|first=C. A.|date=November 1975|pages= 1125–1131 |doi= 10.1172/JCI108187|pmid=1184739|volume=56|issue=5|journal=J. Clin. Invest.}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Folate deficiency|Folate-deficiency anemia]] || {{ICD10|D|52||d|50}} {{ICD10|E|53|8|e|50}} || {{DiseasesDB|4894||none}} || |- |colspan="6"| Folate-deficiency anemia (also known as dietary folate-deficiency anemia) is a condition that develops when the body does not have the adequate supply of [[folic acid]] available that is needed for the production of new healthy blood cells.<ref>{{cite web|url=https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001578/|archive-url=https://web.archive.org/web/20120910060340/http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001578/|url-status=dead|archive-date=September 10, 2012|title=Folate-deficiency anemia|date=31 January 2010|work=National Center for Biotechnology Information|publisher=U.S. National Library of Medicine|accessdate=2 March 2011}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Nutritional megaloblastic anemia]] || {{ICD10|D|51|1|d|50}}, {{ICD10|D|52|0|d|50}}, {{ICD10|D|53|1|d|50}} || {{DiseasesDB|29507||none}} || D000749 |- |colspan="6"| Nutritional Megaloblastic anemia is an anemia (of [[macrocytic anemia|macrocytic]] classification) that results from inhibition of [[DNA synthesis]] in red blood cell production.<ref name="urlMegaloblastic Anemia: Overview - eMedicine Hematology"/> |- |colspan="6" bgcolor="#6699CC"| |- | [[Folate deficiency|Drug-induced folate deficiency anemia]] || {{ICD10|D|52|1|d|50}} || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Protein-deficiency anemia]] || || || |- |colspan="6"| Protein deficiency anemia is an anemia that results from an inadequate intake of dietary protein.<ref>{{cite journal|url=http://www.jpeds.com/article/S0022-3476%2861%2980237-0/abstract|title=Anemia associated with protein deficiency|volume=59|issue=4|pages=533–42|last=Shahidi|first=Nasrollah T.|author2=Diamond, Louis K |author3=Shwachman, Harry |date=October 1961|journal=The Journal of Pediatrics|publisher=Elsevier Inc|accessdate=28 March 2011|pmid=13911137|doi=10.1016/s0022-3476(61)80237-0|url-access=subscription}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- | [[Scurvy]] || {{ICD10|E|54||e|50}} || {{DiseasesDB|13930||none}} || |- |colspan="6"| Scurvy is a disease resulting from a deficiency of vitamin C,<ref>{{cite web|url=https://www.medlineplus.gov/ency/article/000355.htm|title=Scurvy|last=Vorvick, MD|first=Linda|date=March 14, 2009|work=Medline Plus|publisher=U.S. National Library of Medicine|access-date=1 March 2011}}</ref> which is required for the synthesis of collagen in humans. |- |colspan="6" bgcolor="#6699CC"| |- |}
===Non-nutritional (hemolytic, aplastic and other) anemias=== {| class="wikitable" style="width:100%; margin-right:auto; background: #FFFFFF;" |- style="color:white" !style="background-color:#6699CC; width:55%"| Condition name !style="background-color:#6699CC; width:25%"| ICD-10 coding number !style="background-color:#6699CC; width:10%"| Diseases Database coding number !style="background-color:#6699CC; width:10%"| Medical Subject Headings |- |[[Acanthocytosis]] || || || |- |colspan="6"| Acanthocytosis can refer generally to the presence of this type of [[crenation|crenated]] [[red blood cell]], such as may be found in severe cirrhosis or pancreatitis,<ref name="Hillman_2011_5">{{Cite book | last=Hillman | first=RS |author2=Ault, KA |author3=Leporrier, M |author4= Rinder, HM. | title=Hematology in Clinical Practice | publisher=McGraw-Hill | year=2011 |edition=5th | isbn=978-0-07-162699-6}}</ref>{{rp|150}} but can refer specifically to [[abetalipoproteinemia]], a clinical condition with acanthocytic red blood cells, neurologic problems and steatorrhea.<ref name="Harrison_2012_18">{{Cite book | last=Longo | first=D |author2=Fauci, AS |author3=Kasper, DL |author4=Hauser, SL |author5=Jameson, JL |author6= Loscalzo J. | title=Harrison's Principles of Internal Medicine | publisher=McGraw-Hill | year=2012 |edition=18th | isbn=978-0-07174889-6 }}</ref>{{rp|2464}} This particular cause of acanthocytosis (also known as abetalipoproteinemia, apolipoprotein B deficiency, and Bassen-Kornzweig syndrome) is a rare, genetically inherited, autosomal recessive condition due to the inability to fully digest dietary fats in the intestines as a result of various mutations of the [[microsomal triglyceride transfer protein]] (MTTP) gene.<ref>{{cite web|url=https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0002631/|archive-url=https://web.archive.org/web/20110228041951/http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0002631|url-status=dead|archive-date=February 28, 2011|title=Bassen-Kornzweig syndrome|last=Haldeman-Englert|first=C|author2=Zieve, D. |date=4 August 2011|work=Pub Med Health|publisher=National Center for Biotechnology Information, U.S. National Library of Medicine}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Acute posthemorrhagic anemia]] ||{{ICD10|D|62|0|d|60}} || || |- |colspan="6"| Acute posthemorrhagic anemia (also known as acute blood loss anemia) is a condition in which a person quickly loses a large volume of circulating hemoglobin. Acute blood loss is usually associated with an incident of trauma or a severe injury resulting in a large loss of blood. It can also occur during or after a surgical procedure.<ref>{{cite book|last=Turgeon|first=Mary|title=Clinical Hematology: Theory and Procedures|publisher=Lippincott Williams & Wilkins|location=Philadelphia|year=2005|edition=4th|pages=117|chapter=8|isbn=0-7817-5007-5}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Alpha-thalassemia]] || {{ICD10|D|56|0|d|55}} || {{DiseasesDB|448||none}}, {{DiseasesDB|33334||none}}, {{DiseasesDB|33678||none}} || |- |colspan="6"|Alpha-thalassemia (α-thalassemia) is a form of [[thalassemia]] involving the genes [[HBA1]]<ref>{{OMIM|141800}}</ref> and [[HBA2]].<ref>{{OMIM|141850}}</ref> It is condition that causes a reduction of hemoglobin production. There are two types of Alpha-thalassemia, named hemoglobin Bart hydrops fetalis syndrome (also known as Hb Bart syndrome) and HbH disease.<ref>{{cite web|url=https://medlineplus.gov/genetics/condition/alpha-thalassemia/|title=Alpha thalassemia|date=February 27, 2011|work=Genetics Home Reference|publisher=U.S. National Library of Medicine|access-date=3 March 2011}}</ref> |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Anemia]] || {{ICD10|D|50||d|50}}-{{ICD10|D|64||d|60}} || {{DiseasesDB|663||none}} || |- |colspan="6"| Anemia is a type of medical condition that results in a decrease in the number of [[red blood cell]]s (RBCs) or less than the normal quantity of [[hemoglobin]] in the blood.<ref name=medterms /> |- |colspan="6" bgcolor="#6699CC"| |- |[[Anemia of chronic disease]] || || || |- |colspan="6"| Anemia of chronic disease (ACD) (also known as anemia of inflammatory response) is a condition where the body converts iron into unused ferrin, causing a drop in hemoglobin production, and as a result; decreased red blood cell production and count. This is caused by a natural defense mechanism initiated by an inflammatory response in response to the underlying chronic disease.<ref>{{cite web|url=http://www.irondisorders.org/anemia-of-chronic-disease|title=Anemia of Chronic Disease|year=2009|publisher=Iron Disorders Institute|accessdate=3 March 2011}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Erythropoietin#Anemia due to chronic kidney disease|Anemia in kidney disease and dialysis]] || || || |- |colspan="6"| Anemia in kidney disease and dialysis results from the diseased kidney's inability to produce enough of the hormone erythropoietin. Erythropoietin is used to stimulate an adequate production of red blood cells from the bone marrow.<ref>{{cite web|url=http://kidney.niddk.nih.gov/kudiseases/pubs/anemia/|archive-url=https://web.archive.org/web/20041025065452/http://kidney.niddk.nih.gov/kudiseases/pubs/anemia/|url-status=dead|archive-date=October 25, 2004|title=Anemia in Kidney Disease and Dialysis|date=October 2008|work=The National Kidney and Urologic Diseases Information Clearinghouse|publisher=National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health|accessdate=28 March 2011}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Anemia of prematurity]] || {{ICD10|P|61|2|p|50}} || || |- |colspan="6"| Anemia of prematurity is a form of [[anemia]] affecting preterm infants<ref name="pmid20463861">{{cite journal |vauthors=Widness JA |title=Pathophysiology of Anemia During the Neonatal Period, Including Anemia of Prematurity |journal=NeoReviews |volume=9 |issue=11 |page=e520 |date=November 2008 |pmid=20463861 |pmc=2867612 |doi=10.1542/neo.9-11-e520 }}</ref> with decreased [[hematocrit]].<ref name="urlAnemia of prematurity">{{cite web |url=https://www.uptodate.com/contents/anemia-of-prematurity|title=Anemia of prematurity |accessdate=2010-05-31}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Aplastic anemia]] || {{ICD10|D|60||d|60}}-{{ICD10|D|61||d|60}} || {{DiseasesDB|866||none}} || |- |colspan="6"| Aplastic anemia is a condition where bone marrow does not produce sufficient new [[cell (biology)|cell]]s to replenish [[blood cells]].<ref>[http://www.mountsinai.org/Patient%20Care/Service%20Areas/Cancer/Diseases%20and%20Conditions?citype=Disease&ciid=Aplastic%20anemia Aplastic anemia] {{Webarchive|url=https://web.archive.org/web/20090422075547/http://www.mountsinai.org/Patient%20Care/Service%20Areas/Cancer/Diseases%20and%20Conditions?citype=Disease&ciid=Aplastic%20anemia |date=2009-04-22 }} at [[Mount Sinai Hospital, New York|Mount Sinai Hospital]]</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Autoimmune hemolytic anemia]] || {{ICD10|D|59|0|d|55}}-{{ICD10|D|59|1|d|55}} || || |- |colspan="6"| Autoimmune hemolytic anemia (AIHA) is a type of [[hemolytic anemia]] where the body's immune system attacks its own [[red blood cells]] (RBCs), leading to their destruction ([[hemolysis]]).<ref>[http://www.mountsinai.org/patient-care/health-library/diseases-and-conditions/autoimmune-hemolytic-anemia] at [[Mount Sinai Hospital, New York|Mount Sinai Hospital]]</ref><ref name="urlHemolytic Anemia: Overview - eMedicine Hematology">{{cite web |url=http://emedicine.medscape.com/article/201066-overview |title=Hemolytic Anemia: Overview - eMedicine Hematology |accessdate=2009-02-07}}</ref> Types of AIHA include [[warm autoimmune hemolytic anemia]], [[cold agglutinin disease]], and [[paroxysmal cold hemoglobinuria]]. |- |colspan="6" bgcolor="#6699CC"| |- |[[Beta-thalassemia]] || {{ICD10|D|56|1|d|55}} || {{DiseasesDB|3087||none}} || |- |colspan="6"| Beta-thalassemia (β-thalassemia) is an autosomal dominant blood condition that results in the reduction of hemoglobin production. The cause for the disorder is related to a genetic mutation of the HBB gene. This gene is responsible for providing the instructions to produce beta-globin; one of the major components of hemoglobin. The two classification types of beta thalassemia are thalassemia major (also known as Cooley's anemia) and thalassemia intermedia.<ref>{{cite web|url=https://medlineplus.gov/genetics/condition/beta-thalassemia/|title=Beta thalassemia|date=March 13, 2011|work=Genetics Home Reference|publisher=U.S. National Library of Medicine, NIH|access-date=21 March 2011}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Diamond–Blackfan anemia]] || {{ICD10|D|61|0|d|60}} || {{DiseasesDB|29062||none}} || |- |colspan="6"| Diamond–Blackfan anemia (DBA), (also known as Blackfan–Diamond anemia and Inherited erythroblastopenia) <ref>{{cite web|url=http://www.orpha.net/data/patho/Pro/en/BlackfanDiamond-FRenPro429.pdf|title=Diamond–Blackfan anemia|last=Tchernia|first=Gilbert|author2=Delauney, J |date=June 2000|publisher=Orpha.net|accessdate=1 January 2010}}</ref> is a [[congenital]] [[erythroid]] [[aplasia]] that usually presents in infancy.<ref name="pmid19191325">{{cite journal |vauthors=Cmejla R, Cmejlova J, Handrkova H, etal |title=Identification of mutations in the ribosomal protein L5 (RPL5) and ribosomal protein L11 (RPL11) genes in Czech patients with Diamond–Blackfan anemia |journal=Hum. Mutat. |volume= 30|issue= 3|pages= 321–7|date=February 2009 |pmid=19191325 |doi=10.1002/humu.20874|s2cid=24607393 |doi-access=free }}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Congenital dyserythropoietic anemia]] ||{{ICD10|D|64|4|d|60}} || || |- |colspan="6"| Congenital dyserythropoietic anemia (CDA) is a generically inherited autosomal recessive (types I and II) or autosomal dominant (type III) blood disorder that affects the normal maturation process of red blood cell production. Mutations to the CDAN1 gene (type I), SEC23B gene (type II), and a currently unknown gene for type III causes a disruption in the normal formation of [[erythropoiesis]], thereby causing a reduction of circulating healthy mature red blood cells.<ref>{{cite web|url=https://medlineplus.gov/genetics/condition/congenital-dyserythropoietic-anemia/|title=Congenital dyserythropoietic anemia|date=July 2009|work=Genetics Home Reference|publisher=U.S. National Library of Medicine, National Institutes of Health|access-date=22 March 2011}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Drug-induced autoimmune hemolytic anemia]] || {{ICD10|D|59|0|d|55}} || || |- |colspan="6"| Drug-induced autoimmune hemolytic anemia is a type of hemolytic anemia in which a mediated immune response triggers IgG and IgM antibody production in regards to the presence of high doses of [[penicillin]] via the [[hapten]] mechanism causing the reduction of red blood cells in the spleen.<ref name="AAFP">{{cite journal|url=http://www.aafp.org/afp/2004/0601/p2599.html|title=Hemolytic Anemia|volume=69|issue=11|pages=2599–2606|last=Dhaliwal|first=Gurpreet |author2=Cornett, Patricia |author3=Tierney, Lawrence|year=2004|journal=American Family Physician |accessdate=28 March 2011|pmid=15202694}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Drug-induced nonautoimmune hemolytic anemia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Glucose-6-phosphate dehydrogenase deficiency]] ||{{ICD10|D|55|0|d|55}} || {{DiseasesDB|19674||none}} || D005955 |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Hemoglobinopathy]] || {{ICD10|D|58|2|d|55}} || {{DiseasesDB|5037||none}} || |- |colspan="6"| Hemoglobinopathy is a kind of [[gene]]tic defect that results in abnormal structure of one of the [[globin]] chains of the [[hemoglobin]] molecule.<ref>{{DorlandsDict|four/000048231|hemoglobinopathy}}</ref> Hemoglobinopathies are inherited single-gene disorders; in most cases, they are inherited as autosomal co-dominant traits.<ref>Weatherall DJ, Clegg JB. Inherited haemoglobin disorders: an increasing global health problem. Bull World Health Organ. 2001;79(8):704-712.</ref> Hemoglobinopathies imply structural abnormalities in the globin proteins themselves.<ref>{{Cite web |url=http://web2.airmail.net/uthman/hemoglobinopathy/hemoglobinopathy.html |title=Hemoglobinopathies and Thalassemias |access-date=2011-03-03 |archive-url=https://web.archive.org/web/20071215043423/http://web2.airmail.net/uthman/hemoglobinopathy/hemoglobinopathy.html |archive-date=2007-12-15 |url-status=dead }}</ref> Hemoglobinopathy variants include [[sickle-cell disease]].<ref>{{cite web|url=http://diabetes.niddk.nih.gov/dm/pubs/hemovari-A1C/index.htm|archive-url=https://web.archive.org/web/20080724165654/http://www.diabetes.niddk.nih.gov/dm/pubs/hemovari-A1C/index.htm|url-status=dead|archive-date=July 24, 2008|title=Sickle Cell Trait and Other Hemoglobinopathies and Diabetes: Important Information for Physicians|date=November 2008|work=National Diabetes Information Clearinghouse|publisher=National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health|accessdate=3 March 2011}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Hemolytic anemia]] || {{ICD10|D|55||d|55}}-{{ICD10|D|59||d|55}} || {{DiseasesDB|5534||none}} || |- |colspan="6"| Hemolytic anemia (also known as haemolytic anaemia) is an anemia due to [[hemolysis]], the abnormal breakdown of red blood cells. A number of different mediating factors can cause this condition; either from within the blood cell itself (intrinsic factors) or outside of the cell (extrinsic factors).<ref>{{cite web|url=https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001597/|archive-url=https://web.archive.org/web/20110215200844/http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001597|url-status=dead|archive-date=February 15, 2011|title=Hemolytic anemia|last=Reviewed by Vorvick|first=Linda J.|author2=Chen, Yi-Bin |date=31 January 2010|work=Pub Med Health|publisher=National Center for Biotechnology Information, U.S. National Library of Medicine|accessdate=24 March 2011}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Congenital hemolytic anemia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Fanconi anemia]] || {{ICD10|D|61|0|d|60}} || {{DiseasesDB|4745||none}} || D005199 |- |colspan="6"| Fanconi anemia is a rare genetic autosomal recessive aplastic anemia that involves chromosomes 9q and 20q.<ref name="Turgeon"/> |- |colspan="6" bgcolor="#6699CC"| |- |[[Hereditary spherocytosis]] || {{ICD10|D|58|0|d|55}} || {{DiseasesDB|5827||none}} || |- |colspan="6"| Hereditary spherocytosis is a genetically transmitted (autosomal dominant) form of [[spherocytosis]], an auto-[[hemolysis|hemolytic]] [[anemia]] characterized by the production of red blood cells that are sphere-shaped rather than bi-concave disk shaped (donut-shaped), and therefore more prone to hemolysis.<ref name="isbn0-7216-0187-1">{{cite book |author1=Cotran, Ramzi S. |author2=Kumar, Vinay |author3=Fausto, Nelson |author4=Nelso Fausto |author5=Robbins, Stanley L. |author6=Abbas, Abul K. |title=Robbins and Cotran pathologic basis of disease |publisher=Elsevier Saunders |location=St. Louis, Mo |year=2005 |pages=625 |isbn=0-7216-0187-1 }}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Hereditary elliptocytosis]] || {{ICD10|D|58|1|d|55}} || {{DiseasesDB|4172||none}} || |- |colspan="6"| Hereditary elliptocytosis (HE) (also known as ovalocytosis), is an inherited blood disorder in which an abnormally large number of circulating red blood cells are elliptical or cigar shaped rather than the typical biconcave disc shape. It is caused in part by mutations in the formation of specific [[spectrin|spectrin tetramers]] or proteins responsible for giving the red blood cell its shape and elasticity causing continued deformation as the cell matures.<ref>{{cite web|url=http://emedicine.medscape.com/article/955827-overview|title=Pediatric Hereditary Elliptocytosis and Related Disorders|last=Tavares|first=Simone|author2=Sills, Richard |date=January 3, 2011|publisher=eMedicine|accessdate=28 March 2011}}</ref> Subtypes of this condition include southeast Asian ovalocytosis and spherocytic elliptocytosis. |- |colspan="6" bgcolor="#6699CC"| |- |[[Hereditary pyropoikilocytosis]] || || || |- |colspan="6"| Hereditary pyropoikilocytosis (HPP) is an autosomal recessive form of hemolytic anemia which typically presents at infancy or early childhood, characterized by abnormal red blood cell morphology including "budding red cells, fragmented red cells, spherocytes, elliptocytes, triangular cells, and other bizarre-shaped red cells."<ref>{{cite book|url=https://books.google.com/books?id=_HFyKIAN2p8C&q=Hereditary+pyropoikilocytosis&pg=PA227|title=Cell membrane: the red blood cell as a model|last=Yawata|first=Yoshihito|year=2003|publisher=Wiley-VCH|page=227|accessdate=11 April 2011|isbn=9783527304639}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Acquired hemolytic anemia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Cold hemagglutinin disease]] || {{ICD10|D|59|1|d|55}} || {{DiseasesDB|2949||none}} || |- |colspan="6"| Cold hemagglutinin disease (also known as cold agglutinin disease and autoimmune anemia due to cold-reactive antibodies)is an [[autoimmune disease]] characterized by the presence of high concentrations of circulating [[antibodies]], usually [[IgM]], directed against [[red blood cell]]s.<ref name="urlCold Agglutinin Disease: Overview - eMedicine Pediatrics: General Medicine">{{cite web |url=http://emedicine.medscape.com/article/954954-overview |title=Cold Agglutinin Disease: Overview - eMedicine Pediatrics: General Medicine |accessdate=2009-02-07}}</ref> It is a form of [[autoimmune hemolytic anemia]], specifically one in which antibodies only bind red blood cells at low body temperatures, typically 28-31 °C. |- |colspan="6" bgcolor="#6699CC"| |- |[[Paroxysmal cold hemoglobinuria]] || {{ICD10|D|59|6|d|55}} || {{DiseasesDB|9679||none}} || |- |colspan="6"| Paroxysmal cold hemoglobinuria (PCH) (also known as Donath-Landsteiner syndrome) is a rare condition characterized by the sudden presence of hemoglobin in the urine (called [[hemoglobinuria]]), typically after exposure to cold temperatures.<ref>{{cite web|url=https://www.medlineplus.gov/ency/article/000557.htm|title=Paroxysmal cold hemoglobinuria (PCH) e|date=March 28, 2010|work=Medline Plus|publisher=U.S. Department of Health and Human Services, National Institutes of Health|access-date=28 March 2011}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Hemolytic-uremic syndrome]] || {{ICD10|D|59|3|d|55}} || {{DiseasesDB|13052||none}} || |- |colspan="6"| Hemolytic-uremic syndrome (HUS) (also known as haemolytic-uraemic syndrome) is a disease characterized by [[hemolytic anemia]], [[acute renal failure]] ([[uremia]]) and a low [[platelet]] count ([[thrombocytopenia]]). It predominantly but not exclusively affects children. Most cases are preceded by an episode of [[diarrhea]] caused by [[Escherichia coli O157:H7|''E. coli'' O157:H7]], which is acquired as a [[foodborne illness]].<ref>{{cite web|url=http://kidney.niddk.nih.gov/kudiseases/pubs/childkidneydiseases/hemolytic_uremic_syndrome/|archive-url=https://web.archive.org/web/20050627081811/http://kidney.niddk.nih.gov/kudiseases/pubs/childkidneydiseases/hemolytic_uremic_syndrome/|url-status=dead|archive-date=June 27, 2005|title=Hemolytic Uremic Syndrome in Children|date=January 2009|work=National Kidney and Urologic Diseases Information Clearinghouse|publisher=National Institutes of Health of the U.S. Department of Health and Human Services|accessdate=4 March 2011}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Hereditary persistence of fetal hemoglobin]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Hereditary stomatocytosis]] || {{ICD10|D|58|8|d|55}} || {{DiseasesDB|29710||none}} || |- |colspan="6"| Hereditary stomatocytosis is a classification of inherited autosomal dominant human conditions which affect the red blood cell, in which the membrane or outer coating of the cell 'leaks' sodium and potassium ions, causing cell lyses and eventual haemolytic anaemia. |- |colspan="6" bgcolor="#6699CC"| |- |[[Hexokinase deficiency]] || {{ICD10|D|55|2|d|55}} || || |- |colspan="6"| Hexokinase deficiency (also known as human erythrocyte hexokinase deficiency) is an anemia-causing condition associated with inadequate [[hexokinase]].<ref>{{cite journal|pmc=371766|title=Human erythrocyte hexokinase deficiency. Characterization of a mutant enzyme with abnormal regulatory properties.|last=Rijksen|first=G|author2=Staal, G E. |date=August 1978|pmid=27532|doi=10.1172/JCI109129|volume=62|issue=2|journal=J. Clin. Invest.|pages=294–301}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Hyperanaemia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Hypochromic anemia]] || || || |- |colspan="6"| Hypochromic anemia is any type of [[anemia]] in which the [[red blood cells]] (erythrocytes) are paler than normal.<ref>{{cite book|url=https://books.google.com/books?id=3H3AIEtvc8YC&q=Hypochromic+anemia+pale+cells&pg=PA962|title=Trauma: Critical Care|last=Wilson, William C.|author2=Grande, Christopher M. |author3=Hoyt, David B. |year=2007|publisher=CRC press|page=962|accessdate=1 April 2011|isbn=9781420016840}}</ref> This is caused by a proportionally reduced amount of hemoglobin present in relation to the size of the red blood cell. |- |colspan="6" bgcolor="#6699CC"| |- |[[Ineffective erythropoiesis]] || || || |- |colspan="6"| Ineffective erythropoiesis is an anemia caused by the premature [[apoptosis]] of the body's mature red blood cells <ref>{{cite journal|pmid=19318943|pmc=3703923|title=Ineffective erythropoiesis and thalassemias|last=Rivella|first=S.|date=May 2009|doi=10.1097/MOH.0b013e32832990a4|volume=16|issue=3|journal=Curr. Opin. Hematol.|pages=187–94}}</ref> and subsequent reduction in an adequate production and full maturation of new healthy red blood cells.<ref>{{Cite journal|title=Ineffective Erythropoiesis|date=September 13, 1962|journal=The New England Journal of Medicine|volume=267|issue=11|pages=565–566|doi=10.1056/NEJM196209132671113}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Macrocytic anemia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Megaloblastic anemia]] || {{ICD10|D|51|1|d|50}}, {{ICD10|D|52|0|d|50}}, {{ICD10|D|53|1|d|50}} || {{DiseasesDB|29507||none}} || |- |colspan="6"| Megaloblastic anemia (or megaloblastic anaemia) is an [[anemia]] of [[macrocytic anemia|macrocytic]] classification that results from inhibition of [[DNA synthesis]] in red blood cell production.<ref name="urlMegaloblastic Anemia: Overview - eMedicine Hematology"/> |- |colspan="6" bgcolor="#6699CC"| |- |[[Microangiopathic hemolytic anemia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Minkowski-Chauffard syndrome]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Myelophthisic anemia]] || {{ICD10|D|61|9|d|60}} || || |- |colspan="6"| Myelophthisic anemia (also known as myelophthisis) is a severe kind of [[anemia]] found in some people with diseases that affect the [[bone marrow]]. Myelophthisis is the displacement of hemopoietic bone-marrow tissue into the peripheral blood,<ref name="urlHematopathology">{{cite web |url=http://library.med.utah.edu/WebPath/HEMEHTML/HEME030.html |title=Hematopathology }}</ref> either by [[fibrosis]], [[tumor]]s or [[granuloma]]s. |- |colspan="6" bgcolor="#6699CC"| |- |[[Neuroacanthocytosis]] || || {{DiseasesDB|29707||none}} || D054546 |- |colspan="6"| Neuroacanthocytosis (also known as Levine-Critchley syndrome) is a group of rare, genetic conditions that are characterized by movement disorders and acanthocytosis.<ref>{{cite web|url=http://www.ninds.nih.gov/disorders/neuroacanthocytosis/neuroacanthocytosis.htm|title=NINDS Neuroacanthocytosis Information Page|date=March 16, 2009|work=National Institute of Neurological Disorders and Stroke|publisher=National Institutes of Health|accessdate=11 April 2011|archive-url=https://web.archive.org/web/20100313054134/http://www.ninds.nih.gov/disorders/neuroacanthocytosis/neuroacanthocytosis.htm|archive-date=13 March 2010|url-status=dead}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Chorea acanthocytosis]] || || {{DiseasesDB|29707||none}} || D054546 |- |colspan="6"| Chorea-acanthocytosis (ChAc)(also known as Levine-Critchley syndrome, acanthocytosis with neurologic disorder, neuroacanthocytosis, and choreoacanthocytosis)<ref>{{cite web|url=http://www.omim.org/entry/200150?search=Chorea%20acanthocytosis|title=CHOREOACANTHOCYTOSIS; CHAC|work=Online Mendelian Inheritance in Man|publisher=Johns Hopkins University|accessdate=11 April 2011}}</ref> is a rare hereditary disease caused by a mutation of the gene that directs structural proteins in red blood cells. It belongs to a group of four diseases characterized as neuroacanthocytosis.<ref>{{cite web|url=https://medlineplus.gov/genetics/condition/chorea-acanthocytosis/|title=Chorea-acanthocytosis|date=May 2008|work=Genetic Home Reference|publisher=U.S. National Library of Medicine, National Institutes of Health|access-date=11 April 2011}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Non sideropenic hypochromic anaemia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Normocytic anemia]] || || || |- |colspan="6"| A normocytic anemia is an anemia with a [[mean corpuscular volume]] (MCV) of 80–100. |- |colspan="6" bgcolor="#6699CC"| |- |[[Paroxysmal nocturnal hemoglobinuria]] || {{ICD10|D|59|5|d|55}} || {{DiseasesDB|9688||none}} || |- |colspan="6"| Paroxysmal nocturnal hemoglobinuria (also known as Marchiafava-Micheli syndrome) is a rare, acquired, life-threatening blood disease, with anemia due to red blood cell destruction, red urine, and [[thrombosis]]. |- |colspan="6" bgcolor="#6699CC"| |- |[[Pyruvate kinase deficiency]] || {{ICD10|D|55|2|d|55}} || {{DiseasesDB|11090||none}} || |- |colspan="6"| Pyruvate kinase deficiency, also called erythrocyte pyruvate kinase deficiency,<ref>{{OMIM|266200}}</ref> is an [[heredity|inherited]] [[metabolic disorder]] of the enzyme [[pyruvate kinase]] which affects the survival of [[red blood cell]]s and causes them to deform into echinocytes on peripheral blood smears. |- |colspan="6" bgcolor="#6699CC"| |- |[[Rh deficiency syndrome]] || || || |- |colspan="6"| Rh deficiency syndrome is a type of hemolytic anemia that involves erythrocytes whom membranes are deficient in Rh antigens. It is considered a rare condition.<ref>{{cite journal|url=http://bloodjournal.hematologylibrary.org/content/82/2/656.full.pdf|title=Structure and expression of the RH locus in the Rh-deficiency syndrome|vauthors=Cherif-Zahar B, Raynal V, Le Van Kim C, D'Ambrosio AM, Bailly P, Cartron JP, Colin Y|volume=82|issue=2|pages=656–62|date=April 6, 2011|journal=Blood|accessdate=7 April 2011|pmid=8329719|doi=10.1182/blood.V82.2.656.656|doi-access=free}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Sickle-cell disease]] || || || |- |colspan="6"|Sickle cell disease is a group of inherited blood disorders, caused by a genetic abnormality in the oxygen-carrying protein [[haemoglobin]] found in [[Red blood cell|red blood cells]].<ref name="NHLBI-2024-intro">{{cite web |date=30 September 2024 |title=What Is Sickle Cell Disease? |url=https://www.nhlbi.nih.gov/health/sickle-cell-disease |access-date=26 October 2024 |website=National Heart, Lung, and Blood Institute}}</ref> Under certain circumstances, this leads to the red blood cells adopting an abnormal [[sickle]]-like shape; with this shape, they are unable to deform as they pass through [[Capillary|capillaries]], causing blockages and consequent tissue damage. Sickled cells are quickly eliminated from the bloodstream, causing anemia.<ref name="NHLBI-2024-intro" /> |- |colspan="6" bgcolor="#6699CC"| |- |[[Sideroblastic anemia]] || {{ICD10|D|64|0|d|60}}-{{ICD10|D|64|3|d|60}} || {{DiseasesDB|12110||none}} || |- |colspan="6"| Sideroblastic anemia or sideroachrestic anemia is a disease in which the bone marrow produces ringed [[sideroblast]]s rather than healthy [[red blood cell]]s (erythrocytes).<ref name="pmid18698088">{{cite journal |vauthors=Caudill JS, Imran H, Porcher JC, Steensma DP |title=Congenital sideroblastic anemia associated with germline polymorphisms reducing expression of FECH |journal=Haematologica |volume=93 |issue=10 |pages=1582–4 |date=October 2008 |pmid=18698088 |doi=10.3324/haematol.12597 |doi-access=free }}</ref> It may be caused either by a [[genetic disorder]] or indirectly as part of [[myelodysplastic syndrome]].<ref name="titleSideroblastic Anemias: Anemias Caused by Deficient Erythropoiesis: Merck Manual Professional">{{MerckManual|11|130|c||Sideroblastic Anemias: Anemias Caused by Deficient Erythropoiesis}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Southeast Asian ovalocytosis]] || {{ICD10|D|58|1|d|55}} || {{DiseasesDB|9416||none}} || |- |colspan="6"| Southeast Asian ovalocytosis (also known as stomatocytic ovalocytosis, stomatocytic elliptocytosis, and Melanesian ovalocytosis) is a form of [[hereditary elliptocytosis]] common in some communities in [[Malaysia]] and [[Papua New Guinea]], as it confers some resistance to cerebral falciparum [[malaria]].<ref name="titlePrevention of cerebral malaria in children in Papua New Guinea by southeast Asian ovalocytosis band 3 -- Allen et al. 60 (6): 1056 -- American Journal of Tropical Medicine and Hygiene">{{cite journal |title=Prevention of cerebral malaria in children in Papua New Guinea by southeast Asian ovalocytosis band 3 -- Allen et al. 60 (6): 1056 -- ''American Journal of Tropical Medicine and Hygiene''|journal=The American Journal of Tropical Medicine and Hygiene|volume=60|issue=6|pages=1056–1060|doi=10.4269/ajtmh.1999.60.1056|pmid=10403343|date=June 1999|last1=Weatherall|first1=D. J.|last2=Alpers|first2=M. P.|last3=Clegg|first3=J. B.|last4=Peto|first4=T. E.|last5=Mgone|first5=C. S.|last6=Alexander|first6=N. D.|last7=O'Donnell|first7=A.|last8=Allen|first8=S. J.|doi-access=free}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Spur cell hemolytic anemia]] || || || |- |colspan="6"| Spur cell hemolytic anemia is a form of hemolytic anemia that results when free cholesterol binds to the red blood cell's membrane increasing its surface area, causing later deformities such as rough or thorny projections on the erythrocyte named [[acanthocytes]]. This condition is caused by the deceased liver's decreased ability to esterificate cholesterol.<ref>{{cite journal|url=http://bloodjournal.hematologylibrary.org/content/101/1/3.full|archive-url=https://archive.today/20120710090135/http://bloodjournal.hematologylibrary.org/content/101/1/3.full|url-status=dead|archive-date=July 10, 2012|title=Spur-cell hemolytic anemia in severe alcoholic cirrhosis|volume=101|issue=1|pages=3–4|date=January 1, 2003|journal= Blood|publisher=The American Society of Hematology|accessdate=10 April 2011|doi=10.1182/blood.V101.1.3|url-access=subscription}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Thalassemia]] || {{ICD10|D|56||d|55}} || || D013789 |- |colspan="6"|Thalassaemia is an inherited blood disorder which is caused by genetic mutations that causes the body to make fewer healthy red blood cells and less hemoglobin due to lack of protein chains. |- |colspan="6" bgcolor="#6699CC"| |- |[[Triosephosphate isomerase deficiency]] || {{ICD10|D|55|2|d|55}} || {{DiseasesDB|30116||none}} || |- |colspan="6"| Triosephosphate isomerase (TPI) deficiency is a genetically inherited autosomal recessive condition "characterized bychronic hemolytic anemia, [[cardiomyopathy]], susceptibility to infections, severe neurological dysfunction, and, in most cases, death in early childhood."<ref>{{cite journal|pmc=1762313|title=Triose Phosphate Isomerase Deficiency Is Caused by Altered Dimerization–Not Catalytic Inactivity–of the Mutant Enzymes|last=Ralser|first=Markus|author2=Heeren, Gino |author3=Breitenbach. Michael |author4=Lehrach, Hans |author5= Krobitsch, Sylvia |date=December 20, 2006|journal=PLOS ONE|pmid=17183658|doi=10.1371/journal.pone.0000030|volume=1|issue=1|page=e30|bibcode=2006PLoSO...1...30R|doi-access=free}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Warm autoimmune hemolytic anemia]] || {{ICD10|D|59|1|d|55}} || {{DiseasesDB|29723||none}} || |- |colspan="6"| Warm autoimmune hemolytic anemia is an autoimmune hemolytic anemia (AIHA) characterized by formation of antibodies that attack the body's own red blood cells in a destructive immune system response.<ref>{{cite web|url=http://www.merckmanuals.com/home/sec14/ch172/ch172f.html|title=Autoimmune Hemolytic Anemia|work=The Merck Manuals: Online Medical Library|publisher=Merck Sharp and Dohme|accessdate=25 March 2011}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |}
==Blood cancers== [[Image:Large facial Burkitt's Lymphoma.JPG|thumb|200px|right|Seven-year-old Nigerian boy with Burkitt's lymphoma presenting with a severely ulcerated and swollen jaw]]
A blood cancer or hematological malignancy is a type of malignant cancer that originates, affects, or involves the blood, bone marrow, or lymph nodes.<ref name="CDC1">{{cite web|url=https://www.cdc.gov/cancer/hematologic/|title=Hematologic (Blood) Cancers|publisher=Centers for Disease Control and Prevention|accessdate=25 January 2011}}</ref> These cancers include leukemias, lymphomas, and myelomas. These particular types of cancers can arise as defected mature cell types that have differentiated from hematopoietic precursor cells (often in the bone marrow) and begin to quickly proliferate through the bloodstream where it can then often infiltrate other organs and tissues. Others can involve the formation of tumors from [[lymphoblasts]] from within the lymphoid tissue.<ref>{{cite book|last1=McPhee|first1=Stephen|last2=Ganong|first2=William|title=Pathophysiology of Disease|edition=5th|year=2003|publisher=Lange Medical Books/McGraw-Hill|location=New York|isbn=0-07-144159-X|pages=106–110|chapter=Chapter 5: Neoplasia}}</ref> Incidence of affected people with a form of blood cancer has been steady increasing over recent years; however, due in part to early detection methods and subsequent advancements in the treatment of the diseases, mortality rates have continued to decrease.<ref>{{cite web|url=https://www.cdc.gov/Features/HematologicCancers/|title=Blood Cancers: Leukemia, Lymphoma, and Myeloma|publisher=Centers for Disease Control and Prevention|accessdate=5 April 2011}}</ref>
===[[Lymphoma]]=== {| class="wikitable" style="width:100%; margin-right:auto; background: #FFFFFF;" |- style="color:white" !style="background-color:#6699CC; width:55%"| Condition name !style="background-color:#6699CC; width:25%"| ICD-10 coding number !style="background-color:#6699CC; width:10%"| Diseases Database coding number !style="background-color:#6699CC; width:10%"| Medical Subject Headings |- |[[Hodgkin lymphoma]] || {{ICD10|C|81||c|81}} || 5973 || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Non-Hodgkin lymphoma]] || {{ICD10|C|82||c|81}}-{{ICD10|C|85||c|81}} || 9065 || |- |colspan="6"| The non-Hodgkin lymphomas (NHLs) are a diverse group of [[hematological malignancy|blood cancers]] that include any kind of [[lymphoma]] except [[Hodgkin's lymphoma]]s.<ref>{{DorlandsDict|nine/000954456|non-Hodgkin lymphomas}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Anaplastic large cell lymphoma]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Angioimmunoblastic T-cell lymphoma]] || {{ICD10|C|84|4|c|81}} || || |- |colspan="6"| Angioimmunoblastic T-cell lymphoma (AILT) (also known as Angioimmunoblastic lymphadenopathy with dysproteinemia)<ref name=Andrews>{{cite book |author1=James, William D. |author2=Berger, Timothy G. |title=Andrews' Diseases of the Skin: clinical Dermatology |publisher=Saunders Elsevier |year=2006 |isbn=0-7216-2921-0 }}</ref>{{rp|747}} is a mature [[T-cell]] [[lymphoma]] with systemic characterized by a polymorphous [[lymph node]] infiltrate showing a marked increase in [[follicular dendritic cells]] (FDCs) and [[high endothelial venules]] (HEVs) and systemic involvement.<ref name=who1/> It is also known as immunoblastic lymphadenopathy (Lukes-Collins Classification) and AILD-type (lymphogranulomatosis X) T-cell lymphoma (Kiel Classification).<ref name=who1>{{citation |mode=cs1 |editor=Jaffe E.S. |editor2=Harris N.L. |editor3=Stein H. |editor4=Vardiman J.W. |title=World Health Organization Classification of Tumors. Pathology and Genetics of Tumours of Haemopoietic and Lymphoid Tissues |publisher=IARC Press |location=Lyon |date=2001 |isbn=92-8322411-6}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Hepatosplenic T-cell lymphoma]] || || || |- |colspan="6"| Hepatosplenic T-cell lymphoma is a systemic [[neoplasm]] comprising medium-sized cytotoxic [[T-cells]] that show a significant sinusoidal infiltration in the [[liver]], [[spleen]], and [[bone marrow]].<ref>{{cite book |author=Elaine Sarkin Jaffe |author2=Nancy Lee Harris |author3=World Health Organization |author4=International Agency for Research on Cancer |author5=Harald Stein |author6=J.W. Vardiman |title=Pathology and genetics of tumours of haematopoietic and lymphoid tissues |publisher=IARC Press |location=Lyon |year=2001 |series=World Health Organization Classification of Tumors |volume=3 |isbn=92-832-2411-6 |url=https://books.google.com/books?id=XSKqcy7TUZUC}}</ref> It is a rare and generally incurable form of [[lymphoma]].<ref>{{cite journal |vauthors=Mackey AC, Green L, Liang LC, Dinndorf P, Avigan M |title=Hepatosplenic T cell lymphoma associated with infliximab use in young patients treated for inflammatory bowel disease |journal=J. Pediatr. Gastroenterol. Nutr. |volume=44 |issue=2 |pages=265–7 |date=February 2007 |pmid=17255842 |doi=10.1097/MPG.0b013e31802f6424 |doi-access=free }}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[B-cell lymphoma]]|| || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[reticuloendotheliosis]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[reticulosis]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Microglioma]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Diffuse large B-cell lymphoma]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Follicular lymphoma]] || {{ICD10|C|82||c|81}} || || |- |colspan="6"| Follicular lymphoma (also known as [[Indolent condition|indolent]] follicular lymphoma) is a type of non-Hodgkin's lymphoma that involves both large and small B-cell lymphocytes that spreads from the lymphatic system and into the blood, bone marrow, and internal organs. Approximately 20 to 30 percent of non-Hodgkin's lymphomas are diagnosed as follicular lymphoma, with a majority of cases involving those 60 years of age or older.<ref>{{cite web|url=http://www.lymphoma.org/atf/cf/%7B0363cdd6-51b5-427b-be48-e6af871acec9%7D/INDOLENT%20FOLLICULAR.PDF|title=Getting The Facts: Indolent Follicular Lymphoma|last=O'Connor|first=Owen A.|author2=Vose, Julie M. |date=March 2008|publisher=Lymphoma Research Foundation|accessdate=2 April 2011}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Mucosa-associated lymphatic tissue lymphoma]] || || 31339 || |- |colspan="6"| Mucosa-associated lymphatic tissue lymphoma (as known as MALT lymphoma and extra-nodal marginal zone lymphoma) is a condition in which lymphatic tissue abnormally presents outside the lymphatic system (extra-nodular) and instead within the [[mucosa]] of the [[gastrointestinal tract]], typically as a lesion in the stomach.<ref>{{cite journal|title=Mucosa associated lymphoid tissue lymphoma presenting within a solitary anti-mesenteric dilated segment of ileum: a case report|last=Storey|first=Rowland |author2=Gatt, Marcell |author3=Bradford, Ian|date=January 6, 2009|journal=Journal of Medical Case Reports|volume=3|pages=6|publisher=BioMed Central|doi=10.1186/1752-1947-3-6|pmid=19126231|pmc=2627909 |doi-access=free }}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[B-cell chronic lymphocytic leukemia]] || {{ICD10|C|91|1|c|81}} || 2641 || |- |colspan="6"| B-cell chronic lymphocytic leukemia (also known as small cell lymphocytic lymphoma) is a blood cancer that involves the B-cell lymphocytes; responsible for the creation of antibodies. Of the two general types of chronic lymphocytic leukemias (the other involving T-cells), B-cell chronic lymphocytic leukemia accounts for approximately 95 percent of the diagnoses.<ref>{{cite web|url=http://www.cancer.net/patient/Cancer+Types/Leukemia+-+Chronic+Lymphocytic+-+CLL|title=Leukemia - Chronic Lymphocytic - CLL|date=December 2, 2010|work=Cancer.Net|publisher=American Society of Clinical Oncology (ASCO)|accessdate=2 April 2011}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Mantle cell lymphoma]] || {{ICD10|C|85|7|c|81}} || || |- |colspan="6"| Mantle cell lymphoma (MCL) is a type of B-cell lymphoma and one of the rarest forms of non-Hodgkin's lymphomas comprising approximately 6% of diagnosed cases.<ref>{{cite book|author=Turgeon, Mary Louise|title=Clinical hematology: theory and procedures|publisher=Lippincott Williams & Wilkins|location=Hagerstown, MD|year=2005|page=283|isbn=0-7817-5007-5}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Burkitt lymphoma]] || {{ICD10|C|83|7|c|81}} || 1784 || |- |colspan="6"| Burkitt lymphoma (also known as Burkitt's tumor or malignant lymphoma, Burkitt's type) is a type of B-cell lymphoma that is categorized into one of variant types. These variants are endemic (occurring in equatorial Africa), sporadic ("non-African"), and immunodeficiency-associated (usually associated with [[HIV]]). |- |colspan="6" bgcolor="#6699CC"| |- |[[Mediastinal large B cell lymphoma]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Waldenström's macroglobulinemia]] || {{ICD10|C|88|0|c|81}} || 14030 || |- |colspan="6"| Waldenström's macroglobulinemia (also known as lymphoplasmacytic lymphoma) is a lymphoproliferative disease that involves an abnormal increase of lymphocytes within the bone marrow, creasing disruption of normal red blood cell production.<ref>{{cite web|url=http://www.mayoclinic.org/waldenstroms-macroglobulinemia/|title=Waldenström Macroglobulinemia|work=Mayo Clinic|publisher=Mayo Foundation for Medical Education and Research|accessdate=4 April 2011}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Nodal marginal zone B cell lymphoma]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Splenic marginal zone lymphoma]] || || || |- |colspan="6"| Splenic marginal zone lymphoma (SMZL) (also known as well-differentiated lymphocytic lymphoma, small lymphocytic lymphoma, and splenic lymphoma with circulating villous lymphocytes) is a lymphoma made up of small [[B-cells]] that replace the normal architecture of the [[white pulp]] of the [[spleen]]. The neoplastic cells are both small lymphocytes and larger, transformed blasts, and they invade the [[mantle zone]] of [[splenic]] [[lymph follicle|follicles]] and erode the [[marginal zone]], ultimately invading the red pulp of the spleen. Frequently, the bone marrow and [[splenic]] [[hilum (anatomy)|hilar]] [[lymph nodes]] are involved along with the peripheral blood.<ref>{{cite journal|title=Splenic marginal zone lymphoma|volume=101|issue=7|pages=2464–2472|last=Franco|first=Vito|author2=Florena, Ada Maria |author3=Iannitto, Emilio |date=November 21, 2002|journal= Blood|publisher=American Society of Hematology|doi=10.1182/blood-2002-07-2216|pmid=12446449|s2cid=17178824 |doi-access=free}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Intravascular large B-cell lymphoma]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Primary effusion lymphoma]] || || 33904 || |- |colspan="6"| Primary effusion lymphoma is a condition caused by [[Kaposi's sarcoma-associated herpesvirus]] (KSHV).<ref>{{cite journal|title=Primary-Effusion Lymphoma and Kaposi's Sarcoma in a Cardiac-Transplant Recipient|volume=339|issue=7|pages=444–9|last=Jones|first=Dan|author2=Ballestas, Mary E. |author3=Kaye, Kenneth M. |author4=Gulizia, James M. |author5=Winters, Gayle L. |author6=Fletcher, Jonathan |author7=Scadden, David T. |author8=Aster, Jon C. |date=August 13, 1998|journal=The New England Journal of Medicine|publisher=Massachusetts Medical Society.|doi=10.1056/NEJM199808133390705|pmid = 9700178|doi-access=free}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Lymphomatoid granulomatosis]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Nodular lymphocyte predominant Hodgkin's lymphoma]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |}
===[[Leukemia]]=== Leukemia is a malignancy producing of white blood cells in bone marrow. It can be a serious disease if not treated early. Sometimes it can be cured by [[chemotherapy]] or [[Stem-cell therapy|stem cell treatment]]. It can affect our bloodstream, skin, lymph nodes, heart, and brain.
{| class="wikitable" style="width:100%; margin-right:auto; background: #FFFFFF;" |- style="color:white" !style="background-color:#6699CC; width:55%"| Condition name !style="background-color:#6699CC; width:25%"| ICD-10 coding number !style="background-color:#6699CC; width:10%"| Diseases Database coding number !style="background-color:#6699CC; width:10%"| Medical Subject Headings |- |[[Plasma cell leukemia]] || {{ICD10|C|90|1|c|81}} || || D007952 |- |colspan="6"| Plasma cell leukemia (PCL), a [[lymphoproliferative disorder]],<ref name="pmid19192311">{{cite journal |vauthors=Chan SM, George T, Cherry AM, Medeiros BC |title=Complete remission of primary plasma cell leukemia with bortezomib, doxorubicin, and dexamethasone: a case report |journal=Cases J |volume=2 |issue=1 |page=121 |date=February 2009 |pmid=19192311 |doi=10.1186/1757-1626-2-121 |pmc=2644294 |doi-access=free }}</ref> is a rare cancer involving a subtype of white blood cells called [[plasma cells]].<ref name="pmid17538191">{{cite journal |vauthors=Kim SJ, Kim J, Cho Y, Seo BK, Kim BS |title=Combination chemotherapy with bortezomib, cyclophosphamide and dexamethasone may be effective for plasma cell leukemia |journal=Jpn. J. Clin. Oncol. |volume=37 |issue=5 |pages=382–4 |date=May 2007 |pmid=17538191 |doi=10.1093/jjco/hym037 |doi-access=free }}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Acute erythraemia and erythroleukaemia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Acute erythremic myelosis]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Acute erythroid leukemia]] || {{ICD10|C|94|0|c|81}} || || |- |colspan="6"| Acute erythroid leukemia (also known as Guglielmo's disease, and acute Di Guglielmo syndrome) is a rare form of acute myeloid leukemia. |- |colspan="6" bgcolor="#6699CC"| |- |[[Heilmeyer-Schöner disease]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Acute megakaryoblastic leukemia]] || || || D007947 |- |colspan="6"| Acute megakaryoblastic leukemia (AMKL) is a form of acute myeloid leukemia where [[megakaryoblast]]s account for approximately 30% of the nucleated cells within the bone marrow.<ref>{{cite journal|pmid=7496359|title=Acute megakaryoblastic leukemia|last1=Gassmann W|author2=Löffler H. |year=1995|pages=Leukemia and Lymphoma. 18 Suppl 1:69–73|doi=10.3109/10428199509075307|volume=18|journal=Leuk. Lymphoma|first1=Winfried|issue=Suppl 1 }}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Mast cell leukemia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Panmyelosis]] || {{ICD10|C|94|4|c|81}} || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Acute panmyelosis with myelofibrosis]] || {{ICD10|C|94|4|c|81}} || || |- |colspan="6"| Acute panmyelosis with myelofibrosis (APMF) is a poorly defined disorder that arises as either a clonal disorder, or following toxic exposure to the [[bone marrow]]. |- |colspan="6" bgcolor="#6699CC"| |- |[[Lymphosarcoma cell leukemia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Acute leukaemia of unspecified cell type]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Blastic phase chronic myelogenous leukemia]] || || || |- |colspan="6"| Blastic phase chronic myelogenous leukemia is a phase of [[chronic myelogenous leukemia]] in which more than 30% of the cells in the [[blood]] or [[bone marrow]] are [[blast cells]]. |- |colspan="6" bgcolor="#6699CC"| |- |[[Stem cell leukemia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Chronic leukaemia of unspecified cell type]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Subacute leukaemia of unspecified cell type]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Accelerated phase chronic myelogenous leukemia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Acute myeloid leukemia]] ||{{ICD10|C|92|0|c|81}} || 203 || |- |colspan="6"| Acute myeloid leukemia (AML), also known as acute myelogenous leukemia, is a [[cancer]] of the [[myeloid]] line of blood cells, characterized by the rapid growth of abnormal [[white blood cell]]s that accumulate in the [[bone marrow]] and interfere with [[haematopoiesis|the production of normal blood cells]].<ref name=LowenbergDowning1999>{{cite journal|vauthors=Löwenberg B, Downing JR, Burnett A|title=Acute myeloid leukemia|journal=N Engl J Med|volume=341|issue=14|pages=1051–62|date=Sep 30, 1999|pmid=10502596|doi=10.1056/NEJM199909303411407|type=Review}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Polycythemia vera]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Acute promyelocytic leukemia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Acute basophilic leukemia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Acute eosinophilic leukemia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Acute lymphoblastic leukemia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Acute monocytic leukemia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Acute myeloblastic leukemia with maturation]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Acute myeloid dendritic cell leukemia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Adult T-cell leukemia/lymphoma]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Aggressive NK-cell leukemia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[B-cell prolymphocytic leukemia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[B-cell chronic lymphocytic leukemia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[B-cell leukemia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Chronic myelogenous leukemia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Chronic myelomonocytic leukemia]] || || ||p |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Chronic neutrophilic leukemia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Chronic lymphocytic leukemia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Hairy cell leukemia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Chronic idiopathic myelofibrosis]] || || || |- |colspan="6"|[[Myleofibrosis]] is one of the [[myeloproliferative]] [[neoplasms]]. |- |colspan="6" bgcolor="#6699CC"| |}
===[[Myeloma]]=== {| class="wikitable" style="width:100%; margin-right:auto; background: #FFFFFF;" |- style="color:white" !style="background-color:#6699CC; width:55%"| Condition name !style="background-color:#6699CC; width:25%"| ICD-10 coding number !style="background-color:#6699CC; width:10%"| Diseases Database coding number !style="background-color:#6699CC; width:10%"| Medical Subject Headings |- |[[Multiple myeloma]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Kahler's disease]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Myelomatosis]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Solitary myeloma]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Plasma cell leukemia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Plasmacytoma, extramedullary]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Malignant plasma cell tumour NOS]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Plasmacytoma NOS]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |}
===[[Malignant Immunoproliferative Diseases]]=== {| class="wikitable" style="width:100%; margin-right:auto; background: #FFFFFF;" |- style="color:white" !style="background-color:#6699CC; width:55%"| Condition name !style="background-color:#6699CC; width:25%"| ICD-10 coding number !style="background-color:#6699CC; width:10%"| Diseases Database coding number !style="background-color:#6699CC; width:10%"| Medical Subject Headings |- |[[Monoclonal gammopathy]]|| || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Multiple Myeloma]]|| || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |-
|[[Angiocentric immunoproliferative lesion]]|| || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Lymphoid granulomatosis]]|| || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Angioimmunoblastic lymphadenopathy]]|| || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[T-gamma lymphoproliferative disease]]|| || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Waldenström's macroglobulinaemia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Alpha heavy chain disease]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Gamma heavy chain disease]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Franklin's disease]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Immunoproliferative small intestinal disease]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Mediterranean disease]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Malignant immunoproliferative disease, unspecified]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Immunoproliferative disease NOS]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |}
==Coagulation, purpura, and other hemorrhagic conditions== is also related with [[Blood Clot]] {| class="wikitable" style="width:100%; margin-right:auto; background: #FFFFFF;" |- style="color:white" !style="background-color:#6699CC; width:55%"| Condition name !style="background-color:#6699CC; width:25%"| ICD-10 coding number !style="background-color:#6699CC; width:10%"| Diseases Database coding number !style="background-color:#6699CC; width:10%"| Medical Subject Headings |- |[[Disseminated intravascular coagulation]] (DIC, defibrination syndrome) || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Protein C deficiency]] || || || |- |colspan="6"| Protein C deficiency is a rare genetic trait that predisposes to [[thrombosis|thrombotic disease]].<ref name="pmid6895379">{{cite journal |vauthors=Griffin JH, Evatt B, Zimmerman TS, Kleiss AJ, Wideman C |title=Deficiency of protein C in congenital thrombotic disease |journal=J. Clin. Invest. |volume=68 |issue=5 |pages=1370–3 |year=1981 |pmid=6895379 |doi=10.1172/JCI110385 |pmc=370934}}</ref> |- |colspan="6" bgcolor="#6699CC"| |- |[[Protein S deficiency]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Factor V Leiden]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Thrombocytosis]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Idiopathic thrombocytopenic purpura]] ||{{ICD10|D|69|3|d|65}} ||6673 ||D016553 |- |colspan="6"| Idiopathic thrombocytopenic purpura (ITP) is the condition of having a low [[platelet]] [[platelet count|count]] ([[thrombocytopenia]]) of no known cause ([[idiopathic]]). |- |colspan="6" bgcolor="#6699CC"| |- |[[Thrombosis|Recurrent thrombosis]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Hemophilia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Hemophilia A]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Hemophilia B]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Hemophilia C]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Von Willebrand disease]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Antiphospholipid syndrome]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Thrombocytopenia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Glanzmann's thrombasthenia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Wiskott–Aldrich syndrome]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Thrombotic thrombocytopenic purpura]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |}
==Infection-related== Hematological disorders may be caused by a number of infection-related conditions involving the introduction of microorganisms into the host, such as [[bacteria]], [[viruses]], [[microfilaria]], [[fungus]] and [[protozoa]].<ref name="Turgeon">{{cite book|last=Turgeon|first=Mary Louise|title=Clinical Hematology|edition=4th|year=2004|publisher=Lippincott Williams & Wilkins|isbn=0-7817-5007-5|page=161|chapter=12}}</ref>
===Bacterium-related=== {| class="wikitable" style="width:100%; margin-right:auto; background: #FFFFFF;" |- style="color:white" !style="background-color:#6699CC; width:55%"| Condition name !style="background-color:#6699CC; width:25%"| ICD-10 coding number !style="background-color:#6699CC; width:10%"| Diseases Database coding number !style="background-color:#6699CC; width:10%"| Medical Subject Headings |- |[[Clostridium|''Clostridium'' infection]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Cholera|Cholera infection]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[E. coli 0157:H7|''E. coli 0157:H7'' infection]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Typhoid fever]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |}
===Protozoan-related=== {| class="wikitable" style="width:100%; margin-right:auto; background: #FFFFFF;" |- style="color:white" !style="background-color:#6699CC; width:55%"| Condition name !style="background-color:#6699CC; width:25%"| ICD-10 coding number !style="background-color:#6699CC; width:10%"| Diseases Database coding number !style="background-color:#6699CC; width:10%"| Medical Subject Headings |- |[[Leishmania|''Leishmania'' infection]] || || ||* |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Malaria infection]] (''Plasmodium'' infection) || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Toxoplasmosis]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |}
==Immune system regulation-related== ===Immunodeficiency with predominantly antibody defects=== {| class="wikitable" style="width:100%; margin-right:auto; background: #FFFFFF;" |- style="color:white" !style="background-color:#6699CC; width:55%"| Condition name !style="background-color:#6699CC; width:25%"| ICD-10 coding number !style="background-color:#6699CC; width:10%"| Diseases Database coding number !style="background-color:#6699CC; width:10%"| Medical Subject Headings |- |[[hypogammaglobulinemia|Hereditary hypogammaglobulinemia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[hypogammaglobulinemia|Nonfamilial hypogammaglobulinemia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Selective deficiency of immunoglobulin A|Selective deficiency of immunoglobulin A [IgA]]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Selective deficiency of immunoglobulin G|Selective deficiency of immunoglobulin G [IgG] subclasses]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Selective deficiency of immunoglobulin M|Selective deficiency of immunoglobulin M [IgM]]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Immunodeficiency with increased immunoglobulin M|Immunodeficiency with increased immunoglobulin M [IgM]]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[hyperimmunoglobulinaemia|Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinemia]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |[[Transient hypogammaglobulinemia of infancy]] || || || |- |colspan="6"| |- |colspan="6" bgcolor="#6699CC"| |- |}
==References== {{Reflist|colwidth=30em}}
{{Hypersensitivity and autoimmune diseases}} {{Myeloid malignancy}}
{{DEFAULTSORT:Hematologic conditions}} [[Category:Medical lists]] [[Category:Lists of diseases]] [[Category:Blood disorders]]