Alison Goate

{{short description|British neuroscientist}} {{Use dmy dates|date=April 2022}} {{Infobox scientist | name = Alison Goate | image =  | birth_name =  | birth_date =  | death_date =  | nationality = | fields = Neurology, Genetics | workplaces = Icahn School of Medicine Washington University in St. Louis | patrons = | education = University of Oxford (DPhil 1983) University of Bristol | alma_mater = | thesis_title =  | thesis_url =  | thesis_year =  | doctoral_advisor =  | academic_advisors = | doctoral_students = | notable_students = | known_for = Alzheimer's disease, addiction | awards = Potamkin Prize {{small|(1993)}} Metlife Foundation Award {{small|(1994)}} Alzheimer's Association Lifetime Achievement Award {{small|(2015)}} Rainwater Prize(2022) Piepenbrock-DZNE Prize (2023) | author_abbrev_bot = | author_abbrev_zoo = | spouse =  | partner =  | signature =  | signature_alt = | website =  | footnotes = }} '''Alison Mary Goate''' is the Jean C. and James W. Crystal Professor and Chair of the Department of Genetics and Genomic Sciences and Director of the Loeb Center for Alzheimer's Disease at Icahn School of Medicine at Mount Sinai.<ref name="Icahn">{{cite web | title=Alison M Goate | website=Icahn School of Medicine at Mount Sinai | url=https://icahn.mssm.edu/profiles/alison-m-goate | access-date=23 October 2018 | archive-date=23 October 2018 | archive-url=https://web.archive.org/web/20181023195741/https://icahn.mssm.edu/profiles/alison-m-goate | url-status=live }}</ref><ref>{{Cite web|url=https://bcmfamily.bcm.edu/2018/11/05/huffington-center-on-aging-celebrates-30th-anniversary/|title=Huffington Center on Aging celebrates 30th anniversary|date=2018-11-05|website=BCM Family|language=en|access-date=2019-10-18|archive-date=18 October 2019|archive-url=https://web.archive.org/web/20191018212526/https://bcmfamily.bcm.edu/2018/11/05/huffington-center-on-aging-celebrates-30th-anniversary/|url-status=live}}</ref> She was previously professor of genetics in psychiatry, professor of genetics, and professor of neurology at Washington University School of Medicine.<ref name="Goate">{{cite journal | last=Goate | first=Alison | title=Interview | journal=Biomarkers in Medicine | publisher=Future Medicine Ltd | volume=2 | issue=6 | year=2008 | issn=1752-0363 | doi=10.2217/17520363.2.6.541 | pmid=20477443 | pages=541–545}}</ref>

The Goate Lab studies the genetics and molecular bases of Alzheimer's disease, frontotemporal dementia, and alcoholism.<ref>{{cite web |last1=Icahn School of Medicine at Mount Sinai |title=Goate Lab |url=http://labs.neuroscience.mssm.edu/project/goate-lab/ |website=Icahn School of Medicine at Mount Sinai |access-date=26 August 2019 |archive-date=2 September 2019 |archive-url=https://web.archive.org/web/20190902084814/http://labs.neuroscience.mssm.edu/project/goate-lab/ |url-status=live }}</ref>

== Education and early career == After receiving her undergraduate degree in biochemistry at the University of Bristol (UK) and her graduate training at Oxford University (UK), Goate studied under Professors Theodore Puck, Professor Louis Lim and Dr. John Hardy. She received a Royal Society University Research Fellowship to conduct research at St. Mary's Hospital Medical School in London.<ref name="Interview">{{cite journal |last1=Goate |first1=Alison |title=Interview |url=https://insights.ovid.com/biomarkers-medicine/bmed/2008/12/000/interview/11/01319498 |journal=Biomarkers in Medicine |volume=2 |issue=6 |access-date=19 October 2019 |pages=541–545 |doi=10.2217/17520363.2.6.541 |pmid=20477443 |date=December 2008 |archive-date=19 October 2019 |archive-url=https://web.archive.org/web/20191019134058/https://insights.ovid.com/biomarkers-medicine/bmed/2008/12/000/interview/11/01319498 |url-status=live |url-access=subscription }}</ref>

== Awards and affiliations == She has received the Potamkin Prize from the American Academy of Neurology (1993), the Zenith Award from the Alzheimer's Association, Senior Investigator Award from the Metropolitan Life Foundation, the St. Louis Academy of Science Innovation Award, Carl and Gerty Cori Faculty Achievement Award at Washington University in St. Louis (1994), and a Lifetime Achievement Award from the Alzheimer's Association (2015).<ref name=":0">{{Cite journal|last=Goate|first=Alison|date=2 December 2008|title=Interview with Alison Goate|journal=Biomarkers in Medicine|volume=2|issue=6|pages=541–545|doi=10.2217/17520363.2.6.541|issn=1752-0371|pmid=20477443}}</ref> She is a fellow of the American Association for the Advancement of Science.<ref name="Icahn" /> She also serves on the faculty of the Hope Center for Neurological Disorders<ref>{{Cite journal|title=Announcements: Bob Lane Receives Lifetime Achievement Award|date=1998|doi = 10.1037/e404572005-032}}</ref> and is an elected member of the National Academy of Medicine.<ref>{{Cite web|url=https://nam.edu/national-academy-of-medicine-elects-79-new-members/|title=National Academy of Medicine Elects 80 New Members|date=October 17, 2016|website=National Academy of Medicine|url-status=live|archive-url=https://web.archive.org/web/20170106012948/https://nam.edu/national-academy-of-medicine-elects-79-new-members/ |archive-date=2017-01-06 |access-date=October 18, 2019 |last1=Ogilvie |first1=Jenna }}</ref> Goate received the Rainwater Prize for Innovation in Neurodegeneration from the Rainwater Charitable Foundation in 2022.<ref>{{cite web |url=https://rainwatercharitablefoundation.org/rcf-announces-third-annual-rainwater-prize-winners-for-neurodegenerative-research/ |title=RCF Announces Third-Annual Rainwater Prize Winners for Neurodegenerative Research |date=14 December 2021 }}</ref> Goate was the first female to be awarded the Piepenbrock-DZNE Prize for Neurodegenerative disease research in 2023.<ref>{{cite web |url=https://www.dzne.de/en/news/press-releases/press/award-for-dementia-researcher-from-new-york-city/ |title=Award for Dementia Researcher from New York City }}</ref>

== Research == Goate's research centers on the genetics of Alzheimer's disease and related dementias that led to the development of animal and cellular models and the development of anti-amyloid and anti-tau therapies. She has been the principal investigator on four grants and has co-invented and awarded six patents.

=== Patents === *APP770 mutant in alzheimer's disease, (1999).<ref>{{Cite patent|country=US|number=5877015|title=APP770 mutant in Alzheimer's disease|pubdate=1999-03-02|inventor1-last=Hardy|inventor1-first=John Anthony|inventor2-last=Chartier-Harlin|inventor2-first=Marie-Christine|inventor3-last=Goate|inventor3-first=Alison Mary|inventor4=Michael John Owen;Michael John Mullan|assign=Imperial College of Science, Technology and Medicine|inventorlink1=John_Hardy_(geneticist)}}</ref> *Mutant S182 genes, (1999).<ref>{{Cite patent|number=5973133|country=US|title=Mutant S182 genes|pubdate=1999-10-26|inventor1-last=Hardy|inventor1-first=John A.|inventor2-last=Goate|inventor2-first=Alison M.|assign1=Washington University in St. Louis|assign2=University of South Florida|inventorlink1=John_Hardy_(geneticist)}}</ref> *Method for elucidation and detection of polymorphisms, splice variants, and proximal coding mutations using intronic sequences of the Alzheimer's S182 gene, (2000).<ref>{{Cite patent|number=6083694|country=US|title=Method for elucidation and detection of polymorphisms, splice variants, and proximal coding mutations using intronic sequences of the Alzheimer's S182 gene|pubdate=2000-07-04|inventor1-last=Hardy|inventor1-first=John|inventor2-last=Goate|inventor2-first=Alison M.|assign1=Washington University in St. Louis|assign2=University of South Florida|inventorlink1=John_Hardy_(geneticist)}}</ref> *Transgenic mouse expressing an APP-FAD DNA sequence, (2001).<ref>{{Cite patent|number=6300540|country=US|title=Transgenic mouse expressing an APP-FAD DNA sequence|pubdate=2001-10-09|inventor1-last=Hardy|inventor1-first=John Anthony|inventor2-last=Chartier-Harlin|inventor2-first=Marie-Christine|inventor3-last=Goate|inventor3-first=Alison Mary|inventor4=Michael John Owen;Michael John Mullan|assign1=Elan Pharmaceuticals Inc.}}</ref> * Pathogenic Tau mutations, (2002).<ref>{{Cite web |title=Espacenet – search results |url=https://worldwide.espacenet.com/patent/search/family/027374616/publication/US6475723B2?q=pn=US6475723 |access-date=2023-03-16 |website=worldwide.espacenet.com |archive-date=16 March 2023 |archive-url=https://web.archive.org/web/20230316001921/https://worldwide.espacenet.com/patent/search/family/027374616/publication/US6475723B2?q=pn=US6475723 |url-status=live }}</ref> *Markers for addiction, (2011).<ref>{{Cite patent|number=8080371|country=US|title=Markers for addiction|pubdate=2011-12-20|inventor1-last=Ballinger|inventor1-first=Dennis|inventor2-last=Konvicka|inventor2-first=Karel|invent3=Bierut|inventor3-first=Laura Jean|inventor4=John Rice;Frank Scott Saccone;Anthony L. Hinrichs;Alison M. Goate;Jen Wang|assign1=Washington University in St. Louis}}</ref>

=== Grants ===

Partial list:<ref>{{Cite web|url=https://neurotree.org/neurotree/grants.php?pid=36811|title=Alison M. Goate, PhD - US grants|website=Neurotree|url-status=live|archive-url=https://web.archive.org/web/20230316001920/https://neurotree.org/neurotree/grants.php?pid=36811|archive-date=16 March 2023|access-date=September 15, 2019}}</ref>

{|class="wikitable" |- ! Funding Source, Project Title & Number ! Role in Project ! Dates ! Direct Costs |- | NIH/NIA/Columbia University National Institute on Aging Alzheimer's Disease Family-Based Study (NIA-AD FBS) U24AG056270<ref>{{cite web |url=https://reporter.nih.gov/search/Dnc0OPFt_EW6NYGMIc5N_w/project-details/10840010 |title=RePORT ⟩ RePORTER }}</ref> | Subaward PI (MPI) | 8/1/2022 - 4/30/2027 | $151,653 |- | NIH/NIA Neuroprotective Signaling and Transcriptional Pathways in Microglia Associated with Alzheimer's Disease R01AG072489<ref>{{cite web |url=https://reporter.nih.gov/search/Sgp3tafHE0C0Dk8rVfXiFg/project-details/10760227#similar-Projects |title=RePORT ⟩ RePORTER }}</ref> | MPI | 2/1/2022 - 11/30/2026 | $5,972,363 |- | NIH/NINDS Uncovering the Genetic Mechanisms of the Chromosome 17q21.31 Tau haplotype on Neurodegeneration Risk in FTD and PSP U54NS123746<ref>{{cite web |url=https://reporter.nih.gov/search/whVj7vgJPEyke0E_Vxg6gA/project-details/10902613 |title=RePORT ⟩ RePORTER }}</ref> | MPI | 9/1/2021 - 8/31/2026 | $9,278,441 |- | The JPB Foundation

Integrative approaches to the identification of AD risk genes and novel therapeutics 2023-4265 | Principal Investigator | 9/1/2023 - 8/31/2026 | $2,250,000 |- | NIH/NIA/Mayo Clinic

Biology and Pathobiology of ApoE in Aging and Alzheimer's Disease U19AG069701<ref>{{cite web |url=https://reporter.nih.gov/search/DfqcG02fEUaFjGBdcWLJlA/project-details/10407934 |title=RePORT ⟩ RePORTER }}</ref> | Subaward PI (MPI) | 6/1/2021 - 5/31/2026 | $1,885,527 |- | Cure Alzheimer's Foundation

Investigating MEF2C transcription factor as therapeutic targets to reprogram pathological microglial states in Alzheimer's disease<ref>{{cite web |url=https://curealz.org/research/translational/studies-of-innate-immune-pathology/investigating-mef2c-transcription-factor-as-a-therapeutic-target-to-reprogram-pathological-microglial-states-in-alzheimers-disease/ |title=Investigating MEF2C Transcription Factor as a Therapeutic Target to Reprogram Pathological Microglial States in Alzheimer's Disease }}</ref> | Principal Investigator | 1/14/2024 - 1/13/2026 | $201,250 |- | Rainwater Charitable Foundation

Using unbiased proteomics to validate iPSC models of FTD-MAPT and discover novel biomarkers | MPI | 8/1/2023 - 7/31/2025 | $200,000 |- | NIH/NIA/Massachusetts Institute of Technology

Development of PU.1 Inhibitory Modulators as Novel Therapeutics for Alzheimer's Disease U01AG066757<ref>{{cite web |url=https://reporter.nih.gov/search/wUQEfU9jq0KooC8qY0YGNw/project-details/10853048 |title=RePORT ⟩ RePORTER }}</ref> | Subaward PI (MPI) | 5/15/2020 - 4/30/2025 | $1,364,375 |- | NIH/NIA/Banner Health

APOE in the Predisposition to, Protection from and Prevention of Alzheimer's Disease R01AG069453<ref>{{cite web |url=https://reporter.nih.gov/search/XvuYFIkMzkmNQuyUzUSq0Q/project-details/10831026 |title=RePORT ⟩ RePORTER }}</ref> | Subaward PI (MPI) | 7/1/2020 - 3/31/2025 | $71,390 |- | NIH/NIA/University of Pennsylvania

Alzheimer's Disease Genetics Consortium U01AG032984<ref>{{cite web |url=https://reporter.nih.gov/search/r6N-9CLc2U--kjh7jaoj5A/project-details/10137858 |title=RePORT ⟩ RePORTER }}</ref> | Subaward PI | 3/6/2020 - 8/31/2024 | $1,021,752 |- | NIH/NINDS/University of Miami

Reducing Disparities in Dementia and VCID Outcomes in a Multicultural Rural Population<ref>{{cite web |url=https://reporter.nih.gov/search/lx4NNGE-EkWS8JmcRR0cvA/project-details/10612832 |title=RePORT ⟩ RePORTER }}</ref> R01NS101483 | Subaward PI | 4/15/2020 - 3/31/2025 | $78,593 |- | NIH/NIAAA/SUNY

Collaborative Study on the Genetics of Alcoholism (COGA) U10AA008401<ref>{{cite web |url=https://reporter.nih.gov/search/cTdGgGBhkkWyOArUML5JWQ/project-details/10690729 |title=RePORT ⟩ RePORTER }}</ref> | Subaward PI | 9/1/2019 - 8/31/2024 | $2,175,426 |- | M.D. Anderson

Understanding the mechanism of MS4A-dependent AD risk AGR-13139 | Principal Investigator | 8/7/2017 - 8/31/2024 | $3,562,500 |- | NIH/NIA

Genomic Approach to Identification of Microglial Networks Involved in Alzheimer's Disease Risk U01AG058635<ref>{{cite web |url=https://reporter.nih.gov/search/979QVkW5aUC7wp2nMdne9A/project-details/10468712 |title=RePORT ⟩ RePORTER }}</ref> | Principal Investigator | 8/1/2018 - 7/31/2024 | $4,799,685 |- | NIH/NIA/Washington University

DIAN Genetics Core U19AG032438<ref>{{cite web |url=https://reporter.nih.gov/search/3FSlmW_3PkuGfyiqFuTugA/project-details/10665737 |title=RePORT ⟩ RePORTER }}</ref> | Subaward PI and Core Leader | 7/1/2019 - 6/30/2024 | $651,291 |- | Rainwater Charitable Foundation

Investigating rare and common mechanisms underlying tauopathy risk | Principal Investigator | 11/1/2022 - 4/30/2024 | $230,000 |}

== Publications == Semantic Scholar lists 483 publications, 22,943 citations and 1,808 influential citations of Goate's peer-reviewed and original contribution as of 2019.<ref>{{Cite web|url=https://www.semanticscholar.org/author/Alison-M.-Goate/2599501|title=Alison M. Goate - Semantic Scholar|website=www.semanticscholar.org|language=en-US|access-date=2019-10-18|archive-date=18 October 2019|archive-url=https://web.archive.org/web/20191018212525/https://www.semanticscholar.org/author/Alison-M.-Goate/2599501|url-status=live}}</ref>

Partial list: * {{cite journal |pmid=1671712|year=1991|last1=Goate|first1=A.|title=Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease|journal=Nature|volume=349|issue=6311|pages=704–706|display-authors=etal|doi=10.1038/349704a0|bibcode=1991Natur.349..704G|s2cid=4336069}} Cited by 5017 as of October 18, 2019.<ref name=":1">{{Cite web|url=https://scholar.google.com/scholar?hl=en&as_sdt=0,33&q=A+Goate&btnG=|title=Google Scholar|website=scholar.google.com|access-date=2019-10-18|archive-date=16 March 2023|archive-url=https://web.archive.org/web/20230316001948/https://scholar.google.com/scholar?hl=en&as_sdt=0,33&q=A+Goate&btnG=|url-status=live}}</ref> * {{cite journal |pmid=10206645|year=1999|last1=De Strooper|first1=B.|display-authors=etal|title=A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain|journal=Nature|volume=398|issue=6727|pages=518–22|doi=10.1038/19083|bibcode=1999Natur.398..518D|s2cid=4346474}} Cited by 2274 as of October 18, 2019.<ref name=":1" /> * {{cite journal |pmid=17135278|pmc=2270437|year=2007|last1=Saccone|first1=S. F.|display-authors=etal|title=Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPS|journal=Human Molecular Genetics|volume=16|issue=1|pages=36–49|doi=10.1093/hmg/ddl438}} Cited by 793 as of October 18, 2019<ref name=":1" /> * {{cite journal |pmid=17158188|pmc=2278047|year=2007|last1=Bierut|first1=L. J.|display-authors=etal|title=Novel genes identified in a high-density genome wide association study for nicotine dependence|journal=Human Molecular Genetics|volume=16|issue=1|pages=24–35|doi=10.1093/hmg/ddl441}} Cited by 604 as of October 18, 2019.<ref name=":1" /> * {{cite journal |pmid=9931331|year=1999|last1=Kehoe|first1=P.|display-authors=etal|title=A full genome scan for late onset Alzheimer's disease|journal=Human Molecular Genetics|volume=8|issue=2|pages=237–45|doi=10.1093/hmg/8.2.237|doi-access=free}} Cited by 419 as of October 18, 2019<ref name=":1" /> * {{cite journal |pmid=10923994|year=2000|last1=Foroud|first1=T.|display-authors=etal|title=Alcoholism susceptibility loci: Confirmation studies in a replicate sample and further mapping|journal=Alcoholism: Clinical and Experimental Research|volume=24|issue=7|pages=933–45|doi=10.1111/j.1530-0277.2000.tb04634.x}} Cited by 275 as of October 18, 2019.<ref name=":1" /> * {{cite journal |last1=Bierut |first1=LJ |title=ADH1B is associated with alcohol dependence and alcohol consumption in populations of European and African ancestry |journal=Mol Psychiatry |date=2012 |volume=17 |issue=4 |pages=445–450 |doi=10.1038/mp.2011.124 |pmid=21968928 |pmc=3252425 }}.<ref>{{cite journal |last1=Bierut |first1=LJ |title=ADH1B is associated with alcohol dependence and alcohol consumption in populations of European and African ancestry |journal=Mol Psychiatry |date=2012 |volume=17 |issue=4 |pages=445–450 |doi=10.1038/mp.2011.124 |pmid=21968928 |pmc=3252425 }}</ref> *{{cite journal | pmid = 9641683 | doi=10.1038/31508 | volume=393 | issue=6686 | title=Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17 | year=1998 | journal=Nature | pages=702–5 | last1 = Hutton | first1 = M | last2 = Lendon | first2 = CL | last3 = Rizzu | first3 = P | last4 = Baker | first4 = M | last5 = Froelich | first5 = S | last6 = Houlden | first6 = H | last7 = Pickering-Brown | first7 = S | last8 = Chakraverty | first8 = S | last9 = Isaacs | first9 = A | last10 = Grover | first10 = A | last11 = Hackett | first11 = J | last12 = Adamson | first12 = J | last13 = Lincoln | first13 = S | last14 = Dickson | first14 = D | last15 = Davies | first15 = P | last16 = Petersen | first16 = RC | last17 = Stevens | first17 = M | last18 = de Graaff | first18 = E | last19 = Wauters | first19 = E | last20 = van Baren | first20 = J | last21 = Hillebrand | first21 = M | last22 = Joosse | first22 = M | last23 = Kwon | first23 = JM | last24 = Nowotny | first24 = P | last25 = Che | first25 = LK | last26 = Norton | first26 = J | last27 = Morris | first27 = JC | last28 = Reed | first28 = LA | last29 = Trojanowski | first29 = J | last30 = Basun | first30 = H | last31 = Lannfelt | first31 = L | last32 = Neystat | first32 = M | last33 = Fahn | first33 = S | last34 = Dark | first34 = F | last35 = Tannenberg | first35 = T | last36 = Dodd | first36 = PR | last37 = Hayward | first37 = N | last38 = Kwok | first38 = JB | last39 = Schofield | first39 = PR | last40 = Andreadis | first40 = A | last41 = Snowden | first41 = J | last42 = Craufurd | first42 = D | last43 = Neary | first43 = D | last44 = Owen | first44 = F | last45 = Oostra | first45 = BA | last46 = Hardy | first46 = J | last47 = Goate | first47 = A | last48 = van Swieten | first48 = J | last49 = Mann | first49 = D | last50 = Lynch | first50 = T | last51 = Heutink | first51 = P}}.<ref>{{cite journal |pmid=9641683 |date=1998 |last1=Hutton |first1=M. |last2=Lendon |first2=C. L. |last3=Rizzu |first3=P. |last4=Baker |first4=M. |last5=Froelich |first5=S. |last6=Houlden |first6=H. |last7=Pickering-Brown |first7=S. |last8=Chakraverty |first8=S. |last9=Isaacs |first9=A. |last10=Grover |first10=A. |last11=Hackett |first11=J. |last12=Adamson |first12=J. |last13=Lincoln |first13=S. |last14=Dickson |first14=D. |last15=Davies |first15=P. |last16=Petersen |first16=R. C. |last17=Stevens |first17=M. |last18=De Graaff |first18=E. |last19=Wauters |first19=E. |last20=Van Baren |first20=J. |last21=Hillebrand |first21=M. |last22=Joosse |first22=M. |last23=Kwon |first23=J. M. |last24=Nowotny |first24=P. |last25=Che |first25=L. K. |last26=Norton |first26=J. |last27=Morris |first27=J. C. |last28=Reed |first28=L. A. |last29=Trojanowski |first29=J. |last30=Basun |first30=H. |title=Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17 |journal=Nature |volume=393 |issue=6686 |pages=702–705 |doi=10.1038/31508 |bibcode=1998Natur.393..702H |display-authors=1 }}</ref> *{{cite journal |pmid=18288693 |date=2008 |last1=Gitcho |first1=M. A. |last2=Baloh |first2=R. H. |last3=Chakraverty |first3=S. |last4=Mayo |first4=K. |last5=Norton |first5=J. B. |last6=Levitch |first6=D. |last7=Hatanpaa |first7=K. J. |last8=White Cl |first8=3rd |last9=Bigio |first9=E. H. |last10=Caselli |first10=R. |last11=Baker |first11=M. |last12=Al-Lozi |first12=M. T. |last13=Morris |first13=J. C. |last14=Pestronk |first14=A. |last15=Rademakers |first15=R. |last16=Goate |first16=A. M. |last17=Cairns |first17=N. J. |title=TDP-43 A315T mutation in familial motor neuron disease |journal=Annals of Neurology |volume=63 |issue=4 |pages=535–538 |doi=10.1002/ana.21344 |pmc=2747362 }}<ref>{{cite journal |pmid=18288693 |date=2008 |last1=Gitcho |first1=M. A. |last2=Baloh |first2=R. H. |last3=Chakraverty |first3=S. |last4=Mayo |first4=K. |last5=Norton |first5=J. B. |last6=Levitch |first6=D. |last7=Hatanpaa |first7=K. J. |last8=White Cl |first8=3rd |last9=Bigio |first9=E. H. |last10=Caselli |first10=R. |last11=Baker |first11=M. |last12=Al-Lozi |first12=M. T. |last13=Morris |first13=J. C. |last14=Pestronk |first14=A. |last15=Rademakers |first15=R. |last16=Goate |first16=A. M. |last17=Cairns |first17=N. 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{{DEFAULTSORT:Goate, Alison M.}} Category:Living people Category:20th-century British biologists Category:20th-century British women biologists Category:21st-century British biologists Category:21st-century British women biologists Category:Academics of the University of Oxford Category:Alumni of the University of Bristol Category:Alumni of the University of Oxford Category:Alzheimer's disease researchers Category:British geneticists Category:British neuroscientists Category:British women neuroscientists Category:Fellows of the American Association for the Advancement of Science Category:Icahn School of Medicine at Mount Sinai faculty Category:Members of the National Academy of Medicine Category:Psychiatric geneticists Category:Washington University School of Medicine faculty Category:Year of birth missing (living people)