ASAH2C

{{Short description|Ceramidase enzyme}} {{Infobox_gene}} '''Neutral ceramidase C''' also known as '''N-acylsphingosine amidohydrolase 2C''' or '''non-lysosomal ceramidase C''' or '''ASAH2C''' is a ceramidase enzyme which in humans is encoded by the ''ASAH2C'' gene.<ref name="pmid17334805">{{cite journal | vauthors = Avramopoulos D, Wang R, Valle D, Fallin MD, Bassett SS | title = A novel gene derived from a segmental duplication shows perturbed expression in Alzheimer's disease | journal = Neurogenetics | volume = 8 | issue = 2 | pages = 111–20 | date = April 2007 | pmid = 17334805 | doi = 10.1007/s10048-007-0081-5 | s2cid = 20156514 }}</ref>

== References == {{Reflist}}

== Further reading == {{refbegin | 2}} * {{cite journal | vauthors = Choi MS, Anderson MA, Zhang Z, Zimonjic DB, Popescu N, Mukherjee AB | title = Neutral ceramidase gene: role in regulating ceramide-induced apoptosis | journal = Gene | volume = 315 | pages = 113–22 | date = October 2003 | pmid = 14557071 | doi = 10.1016/S0378-1119(03)00721-2 }} * {{cite journal | vauthors = El Bawab S, Roddy P, Qian T, Bielawska A, Lemasters JJ, Hannun YA | title = Molecular cloning and characterization of a human mitochondrial ceramidase | journal = The Journal of Biological Chemistry | volume = 275 | issue = 28 | pages = 21508–13 | date = July 2000 | pmid = 10781606 | doi = 10.1074/jbc.M002522200 | doi-access = free }} * {{cite journal | vauthors = Tani M, Sano T, Ito M, Igarashi Y | title = Mechanisms of sphingosine and sphingosine 1-phosphate generation in human platelets | journal = Journal of Lipid Research | volume = 46 | issue = 11 | pages = 2458–67 | date = November 2005 | pmid = 16061940 | doi = 10.1194/jlr.M500268-JLR200 | doi-access = free }} * {{cite journal | vauthors = Galadari S, Wu BX, Mao C, Roddy P, El Bawab S, Hannun YA | title = Identification of a novel amidase motif in neutral ceramidase | journal = The Biochemical Journal | volume = 393 | issue = Pt 3 | pages = 687–95 | date = February 2006 | pmid = 16229686 | pmc = 1360721 | doi = 10.1042/BJ20050682 }} * {{cite journal | vauthors = Hwang YH, Tani M, Nakagawa T, Okino N, Ito M | title = Subcellular localization of human neutral ceramidase expressed in HEK293 cells | journal = Biochemical and Biophysical Research Communications | volume = 331 | issue = 1 | pages = 37–42 | date = May 2005 | pmid = 15845354 | doi = 10.1016/j.bbrc.2005.03.134 }} * {{cite journal | vauthors = Osawa Y, Uchinami H, Bielawski J, Schwabe RF, Hannun YA, Brenner DA | title = Roles for C16-ceramide and sphingosine 1-phosphate in regulating hepatocyte apoptosis in response to tumor necrosis factor-alpha | journal = The Journal of Biological Chemistry | volume = 280 | issue = 30 | pages = 27879–87 | date = July 2005 | pmid = 15946935 | doi = 10.1074/jbc.M503002200 | doi-access = free }} {{refend}}