{{Short description|Protein found in humans}} {{cs1 config|name-list-style=vanc}} {{Infobox_gene}}
'''ADP/ATP translocase 3''', also known as '''solute carrier family 25 member 6''', is a [[protein]] that in humans is encoded by the ''SLC25A6'' [[gene]].<ref name="pmid14598172">{{cite journal | author = Palmieri F | title = The mitochondrial transporter family (SLC25): physiological and pathological implications | journal = Pflügers Arch. | volume = 447 | issue = 5 | pages = 689–709 |date=February 2004 | pmid = 14598172 | doi = 10.1007/s00424-003-1099-7 | s2cid = 25304722 }}</ref>
Identical copies of this gene reside on the [[pseudoautosomal region]]s of the [[X chromosome|X]] and [[Y chromosome]]s.<ref name="pmid8486369">{{cite journal | vauthors = Slim R, Levilliers J, Lüdecke HJ, Claussen U, Nguyen VC, Gough NM, Horsthemke B, Petit C | title = A human pseudoautosomal gene encodes the ANT3 ADP/ATP translocase and escapes X-inactivation | journal = Genomics | volume = 16 | issue = 1 | pages = 26–33 |date=April 1993 | pmid = 8486369 | doi = 10.1006/geno.1993.1135 }}</ref>
== See also == * [[Adenine nucleotide translocator]] * [[Solute carrier family]]
== References == {{Reflist}}
==Further reading== {{refbegin | 2}} *{{cite journal |vauthors=Jang JY, Lee CE |title=Mitochondrial adenine nucleotide translocator 3 is regulated by IL-4 and IFN-gamma via STAT-dependent pathways |journal=Cell. Immunol. |volume=226 |issue= 1 |pages= 11–9 |year= 2003 |pmid= 14746803 |doi=10.1016/j.cellimm.2003.11.004 }} *{{cite journal |vauthors=Komaki H, Fukazawa T, Houzen H, etal |title=A novel D104G mutation in the adenine nucleotide translocator 1 gene in autosomal dominant progressive external [[ophthalmoparesis|ophthalmoplegia]] patients with mitochondrial DNA with multiple deletions |journal=Ann. Neurol. |volume=51 |issue= 5 |pages= 645–8 |year= 2002 |pmid= 12112115 |doi= 10.1002/ana.10172 |s2cid=38767585 }} *{{cite journal |vauthors=Stelzl U, Worm U, Lalowski M, etal |title=A human protein-protein interaction network: a resource for annotating the proteome |journal=Cell |volume=122 |issue= 6 |pages= 957–68 |year= 2005 |pmid= 16169070 |doi= 10.1016/j.cell.2005.08.029 |hdl= 11858/00-001M-0000-0010-8592-0 |s2cid=8235923 |hdl-access= free }} *{{cite journal |vauthors=Majima E, Takeda M, Miki S, etal |title=Close location of the first loop to the third loop of the mitochondrial ADP/ATP carrier deduced from cross-linking catalyzed by copper-o-phenanthroline of the solubilized carrier with Triton X-100 |journal=J. Biochem. |volume=131 |issue= 3 |pages= 461–8 |year= 2002 |pmid= 11872176 |doi= 10.1093/oxfordjournals.jbchem.a003122|doi-access=free }} *{{cite journal |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |bibcode=2005Natur.437.1173R |s2cid=4427026 }} *{{cite journal |vauthors=Zamora M, Granell M, Mampel T, Viñas O |title=Adenine nucleotide translocase 3 (ANT3) overexpression induces apoptosis in cultured cells |journal=FEBS Lett. |volume=563 |issue= 1–3 |pages= 155–60 |year= 2004 |pmid= 15063741 |doi= 10.1016/S0014-5793(04)00293-5 |bibcode=2004FEBSL.563..155Z |s2cid=36314858 |doi-access=free }} *{{cite journal |vauthors=Hu Z, Guo X, Yu Q, etal |title=Down-regulation of adenine nucleotide translocase 3 and its role in camptothecin-induced apoptosis in human hepatoma QGY7703 cells |journal=FEBS Lett. |volume=583 |issue= 2 |pages= 383–8 |year= 2009 |pmid= 19111545 |doi= 10.1016/j.febslet.2008.12.029 |bibcode=2009FEBSL.583..383H |s2cid=27745530 |doi-access= }} *{{cite journal |vauthors=De Marcos Lousa C, Trézéguet V, Dianoux AC, etal |title=The human mitochondrial ADP/ATP carriers: kinetic properties and biogenesis of wild-type and mutant proteins in the yeast S. cerevisiae |journal=Biochemistry |volume=41 |issue= 48 |pages= 14412–20 |year= 2002 |pmid= 12450408 |doi=10.1021/bi0261490 }} *{{cite journal |vauthors=Zamora M, Ortega JA, Alaña L|title=Apoptotic and anti-proliferative effects of all-trans retinoic acid. Adenine nucleotide translocase sensitizes HeLa cells to all-trans retinoic acid |journal=Exp. Cell Res. |volume=312 |issue= 10 |pages= 1813–9 |year= 2006 |pmid= 16556444 |doi= 10.1016/j.yexcr.2006.02.014 |display-authors=etal}} *{{cite journal |vauthors=Yang Z, Cheng W, Hong L, etal |title=Adenine nucleotide (ADP/ATP) translocase 3 participates in the tumor necrosis factor induced apoptosis of MCF-7 cells |journal=Mol. Biol. Cell |volume=18 |issue= 11 |pages= 4681–9 |year= 2007 |pmid= 17855512 |doi= 10.1091/mbc.E06-12-1161 |pmc=2043556 }} *{{cite journal |vauthors=Tu LC, Yan X, Hood L, Lin B |title=Proteomics analysis of the interactome of N-myc downstream regulated gene 1 and its interactions with the androgen response program in prostate cancer cells |journal=Mol. Cell. Proteomics |volume=6 |issue= 4 |pages= 575–88 |year= 2007 |pmid= 17220478 |doi= 10.1074/mcp.M600249-MCP200 |s2cid=7203032 |doi-access= free}} *{{cite journal |vauthors=Mühlenbein N, Hofmann S, Rothbauer U, Bauer MF |title=Organization and function of the small Tim complexes acting along the import pathway of metabolite carriers into mammalian mitochondria |journal=J. Biol. Chem. |volume=279 |issue= 14 |pages= 13540–6 |year= 2004 |pmid= 14726512 |doi= 10.1074/jbc.M312485200 |doi-access= free }} *{{cite journal |vauthors=Verrier F, Mignotte B, Jan G, Brenner C |title=Study of PTPC composition during apoptosis for identification of viral protein target |journal=Ann. N. Y. Acad. Sci. |volume=1010 |issue= 1|pages= 126–42 |year= 2003 |pmid= 15033708 |doi=10.1196/annals.1299.022 |bibcode=2003NYASA1010..126V |s2cid=22660199 |url=https://hal.archives-ouvertes.fr/hal-03034595/file/FVerrier_AnnAcadSciNY_03%20%281%29.pdf }} *{{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 |pmc=528928 }} *{{cite journal |vauthors=Napoli L, Bordoni A, Zeviani M, etal |title=A novel missense adenine nucleotide translocator-1 gene mutation in a Greek adPEO family |journal=Neurology |volume=57 |issue= 12 |pages= 2295–8 |year= 2001 |pmid= 11756613 |doi= 10.1212/wnl.57.12.2295|s2cid=10284753 }} *{{cite journal |vauthors=Chanturiya AN, Basañez G, Schubert U|title=PB1-F2, an influenza A virus-encoded proapoptotic mitochondrial protein, creates variably sized pores in planar lipid membranes |journal=J. Virol. |volume=78 |issue= 12 |pages= 6304–12 |year= 2004 |pmid= 15163724 |doi= 10.1128/JVI.78.12.6304-6312.2004 |pmc=416516 |display-authors=etal}} *{{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2002 |pmid= 12477932 |doi= 10.1073/pnas.242603899 |pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }} *{{cite journal |vauthors=Jang JY, Lee CE |title=IL-4-induced upregulation of adenine nucleotide translocase 3 and its role in Th cell survival from apoptosis |journal=Cell. Immunol. |volume=241 |issue= 1 |pages= 14–25 |year= 2006 |pmid= 16930576 |doi= 10.1016/j.cellimm.2006.07.006 }} *{{cite journal |vauthors=Zamarin D, García-Sastre A, Xiao X, etal |title=Influenza virus PB1-F2 protein induces cell death through mitochondrial ANT3 and VDAC1 |journal=PLOS Pathog. |volume=1 |issue= 1 |pages= e4 |year= 2005 |pmid= 16201016 |doi= 10.1371/journal.ppat.0010004 |pmc=1238739 |doi-access=free }} *{{cite journal |vauthors=Deniaud A, Brenner C, Kroemer G |title=Mitochondrial membrane permeabilization by HIV-1 Vpr |journal=Mitochondrion |volume=4 |issue= 2–3 |pages= 223–33 |year= 2004 |pmid= 16120388 |doi= 10.1016/j.mito.2004.06.012 }} {{refend}}
{{Membrane transport proteins}}
[[Category:Solute carrier family]]
{{gene-X-stub}}