{{Short description|Class of enzymes}} {{infobox enzyme | Name = 3-phytase | EC_number = 3.1.3.8 | CAS_number = 37288-11-2 | GO_code = 0016158 | image = | width = | caption = }} The enzyme '''3-phytase''' (EC 3.1.3.8) catalyzes the reaction<ref name=":0">{{Cite web|url=https://enzyme.expasy.org/EC/3.1.3.8|title=ENZYME entry 3.1.3.8|website=enzyme.expasy.org|language=en-US|access-date=2018-04-09}}</ref><ref name="Mullaney_2003">{{cite journal | vauthors = Mullaney EJ, Ullah AH | title = The term phytase comprises several different classes of enzymes | journal = Biochemical and Biophysical Research Communications | volume = 312 | issue = 1 | pages = 179–84 | date = December 2003 | pmid = 14630039 | doi = 10.1016/j.bbrc.2003.09.176 | bibcode = 2003BBRC..312..179M }}</ref>
: ''myo''-inositol hexakisphosphate + H<sub>2</sub>O = 1<small>D</small>-''myo''-inositol 1,2,4,5,6-pentakisphosphate + phosphate
''myo''-Inositol hexakisphosphate is also known as phytic acid.
These enzymes belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name '''''myo''-inositol-hexakisphosphate 3-phosphohydrolase'''. Other names in common use include '''1-phytase''', '''phytate 1-phosphatase''', '''phytate 3-phosphatase''', and '''phytate 6-phosphatase'''.<ref name=":0" />
Enzymes of this type participate in inositol phosphate metabolism.
==Structural studies==
As of late 2007, 12 structures have been solved for this class of enzymes, with PDB accession codes {{PDB link|1CVM}}, {{PDB link|1IHP}}, {{PDB link|1POO}}, {{PDB link|1QFX}}, {{PDB link|1QLG}}, {{PDB link|1QWO}}, {{PDB link|1SK8}}, {{PDB link|1SK9}}, {{PDB link|1SKA}}, {{PDB link|1SKB}}, {{PDB link|2GFI}}, and {{PDB link|2POO}}.
== See also ==
* 4-phytase (6-phytase) * 5-phytase * Protein tyrosine phosphatase
==References== {{reflist}} {{Esterases}} {{Enzymes}} {{Portal bar|Biology|border=no}}
Category:EC 3.1.3 Category:Enzymes of known structure
{{3.1-enzyme-stub}}