# Transporter Classification Database

> Mediated Wiki article. Canonical URL: https://mediated.wiki/source/Transporter_Classification_Database
> Markdown URL: https://mediated.wiki/source/Transporter_Classification_Database.md
> Source: https://en.wikipedia.org/wiki/Transporter_Classification_Database
> Source revision: 1353387017
> License: Creative Commons Attribution-ShareAlike 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/)

{{Short description|Classification of membrane proteins including ion channels}}
The '''Transporter Classification Database''' (or '''TCDB''') is an [International Union of Biochemistry and Molecular Biology](/source/International_Union_of_Biochemistry_and_Molecular_Biology) (IUBMB)-approved classification system for [membrane transport protein](/source/membrane_transport_protein)s, including [ion channel](/source/ion_channel)s.<ref>{{cite journal|last1=Saier|first1=Milton H.|last2=Reddy|first2=Vamsee S.|last3=Tamang|first3=Dorjee G.|last4=Västermark|first4=Åke|title=The Transporter Classification Database|journal=Nucleic Acids Research|date=January 2014|volume=42|issue=D1|pages=D251–D258|doi=10.1093/nar/gkt1097|pmid=24225317|url= |pmc=3964967}}</ref><ref>{{cite journal|last1=Saier|first1=M. H.|last2=Yen|first2=M. R.|last3=Noto|first3=K.|last4=Tamang|first4=D. G.|last5=Elkan|first5=C.|title=The Transporter Classification Database: recent advances|journal=Nucleic Acids Research|date=1 January 2009|volume=37|issue=Database|pages=D274–D278|doi=10.1093/nar/gkn862|url= |pmid=19022853|pmc=2686586}}</ref><ref>{{cite journal|last1=Saier|first1=M. H.|last2=Tran|first2=C. V.|last3=Barabote|first3=R. D.|title=TCDB: the Transporter Classification Database for membrane transport protein analyses and information|journal=Nucleic Acids Research|date=1 January 2006|volume=34|issue=90001|pages=D181–D186|doi=10.1093/nar/gkj001|url= |pmid=16381841|pmc=1334385}}</ref>

==Classification==
The upper level of classification and a few examples of proteins with known 3D structure:

===1. [Channels](/source/Ion_channel) and pores===

====1.A α-type channels====
* 1.A.1 [Voltage-gated ion channel superfamily](/source/Voltage-gated_ion_channel)
* 1.A.2 [Inward-rectifier K<sup>+</sup> channel family](/source/inward-rectifier_K%2B_channel)
* 1.A.3 [Ryanodine-inositol-1,4,5-trisphosphate receptor Ca<sup>2+</sup> channel family](/source/Ryanodine-inositol-1%2C4%2C5-trisphosphate_receptor_Ca2%2B_channel)
* 1.A.4 [Transient receptor potential Ca<sup>2+</sup> channel family](/source/Transient_receptor_potential_Ca2%2B_channel)
* 1.A.5 [Polycystin cation channel family](/source/Polycystin_cation_channel_family)
* 1.A.6 [Epithelial Na<sup>+</sup> channel family](/source/Epithelial_sodium_channel)
* 1.A.7 [ATP-gated P2X receptor cation channel family](/source/P2X_purinoreceptor)
* 1.A.8 [Major intrinsic protein superfamily](/source/Major_intrinsic_protein)
* 1.A.9 [Neurotransmitter receptor, Cys loop, ligand-gated ion channel family](/source/Ligand-gated_ion_channel)
* 1.A.10 [Glutamate-gated ion channel family](/source/Glutamate-gated_ion_channel_family) of [neurotransmitter receptor](/source/neurotransmitter_receptor)s
* 1.A.11 [Ammonium channel transporter family](/source/Ammonia_transporter)
* 1.A.12 [Intracellular chloride channel family](/source/Chloride_channel)
* 1.A.13 [Epithelial chloride channel family](/source/Chloride_channel)
* 1.A.14 [Testis-enhanced gene transfer family](/source/Testis-enhanced_gene_transfer_family)
* 1.A.15 [Nonselective cation channel-2 family](/source/Non-selective_cation_channel-2_family)
* 1.A.16 [Formate-nitrite transporter family](/source/Formate-nitrite_transporter)
* 1.A.17 [Calcium-dependent chloride channel family](/source/Calcium-dependent_chloride_channel)
* 1.A.18 [Chloroplast envelope anion-channel-forming Tic110 family](/source/Tic110_family)
* 1.A.19 [Type A influenza virus matrix-2 channel family](/source/M2_proton_channel)
* 1.A.20 [BCL2/Adenovirus E1B-interacting protein 3 family](/source/BNIP3)
* 1.A.21 [Bcl-2 family](/source/Bcl-2_family)
* 1.A.22 [Large-conductance mechanosensitive ion channel](/source/Large-conductance_mechanosensitive_ion_channel)
* 1.A.23 [Small-conductance mechanosensitive ion channel](/source/Small-conductance_mechanosensitive_ion_channel)
* 1.A.24 [Gap-junction-forming connexin family](/source/Connexin)
* 1.A.25 [Gap-junction-forming innexin family](/source/Innexin)
* 1.A.26 [Mg<sup>2+</sup> transporter-E family](/source/Magnesium_transporter_E)
* 1.A.27 [Phospholemman family](/source/Phospholemman)
* 1.A.28 [Urea transporter family](/source/Urea_transporter_family)
* 1.A.29 [Urea/amide channel family](/source/Urea%2Famide_channel_family)
* 1.A.30 [H<sup>+</sup>- or Na<sup>+</sup>-translocating bacterial MotAB flagellar motor/ExbBD outer-membrane transport energizer superfamily](/source/H%2B-_or_Na%2B-translocating_bacterial_MotAB_flagellar_motor%2FExbBD_outer-membrane_transport_energizer_superfamily)
* 1.A.31 [Annexin family](/source/Annexin)
* 1.A.32 [Type B influenza virus NB channel family](/source/Type_B_influenza_virus_NB_channel)
* 1.A.33 [Cation-channel-forming heat shock protein 70 family](/source/heat-shock_protein_70)
* 1.A.34 [''Bacillus'' gap junction-like channel-forming complex family](/source/Bacillus_gap_junction-like_channel-forming_complex_family)
* 1.A.35 [CorA metal ion transporter family](/source/CorA_metal_ion_transporter)
* 1.A.36 [Intracellular chloride channel family](/source/Chloride_channel)
* 1.A.37 [CD20 Ca<sup>2+</sup> channel family](/source/The_CD20_Ca2%2B_channel_family)
* 1.A.38 [Golgi pH regulator family](/source/The_Golgi_pH_regulator_family)
* 1.A.39 [Type C influenza virus CM2 channel family](/source/Type_C_Influenza_Virus_CM2_Channel_(CM2-C)_Family)
* 1.A.40 [Human immunodeficiency virus type I Vpu channel family](/source/Vpu_protein)
* 1.A.41 [Avian reovirus p10 Vvroporin family](/source/Avian_reovirus_p10_Vvroporin_family)
* 1.A.42 [HIV viral protein R family](/source/HIV_viral_protein_R_family)
* 1.A.43 [Camphor resistance or fluoride exporter family](/source/Camphor_resistance_or_fluoride_exporter_family)
* 1.A.44 [Pore-forming tail Tip pb2 protein of phage T5 family](/source/Pore-forming_tail_Tip_pb2_protein_of_phage_T5_family)
* 1.A.45 [Phage P22 injectisome family](/source/Phage_P22_injectisome_family)
* 1.A.46 [Anion channel-forming bestrophin family](/source/Anion_channel-forming_bestrophin_family)
* 1.A.47 [Nucleotide-sensitive anion-selective channel, ICln family](/source/Nucleotide-sensitive_anion-selective_channel%2C_ICln_family)
* 1.A.48 [Anion channel Tweety family](/source/Anion_channel_Tweety_family)
* 1.A.49 [Human coronavirus ns12.9 viroporin family](/source/Human_coronavirus_ns12.9_viroporin_family)
* 1.A.50 [Phospholamban (Ca<sup>2+</sup>-channel and Ca<sup>2+</sup>-ATPase regulator) family](/source/phospholamban)
*1.A.51 The Voltage-gated Proton Channel (VPC) Family
*1.A.52 The Ca<sup>2+</sup> Release-activated Ca<sup>2+</sup> (CRAC) Channel (CRAC-C) Family
*1.A.53 The Hepatitis C Virus P7 Viroporin Cation-selective Channel (HCV-P7) Family
*1.A.54 The Presenilin ER Ca<sup>2+</sup> Leak Channel (Presenilin) Family
*1.A.55 The Synaptic Vesicle-Associated Ca<sup>2+</sup> Channel, Flower (Flower) Family
*1.A.56 The Copper Transporter (Ctr) Family
*1.A.57 The Human SARS Coronavirus Viroporin (SARS-VP)
*1.A.58 The Type B Influenza Virus Matrix Protein 2 (BM2-C) Family
*1.A.59 The Bursal Disease Virus Pore-Forming Peptide, Pep46 (Pep46) Family
*1.A.60 The Mammalian Reovirus Pre-forming Peptide, Mu-1 (Mu-1) Family
*1.A.61 The Insect Nodavirus Channel-forming Chain F (Gamma-Peptide) Family
*1.A.62 The Homotrimeric Cation Channel (TRIC) Family
*1.A.63 The Ignicoccus Outer Membrane α-helical Porin (I-OMP Family
*1.A.64 The Plasmolipin (Plasmolipin) Family
*1.A.65 The Coronavirus Viroporin E Protein (Viroporin E) Family
*1.A.66 The Pardaxin (Pardaxin) Family
*1.A.67 The Membrane Mg<sup>2+</sup> Transporter (MMgT) Family 
*1.A.68 The Viral Small Hydrophobic Viroporin (V-SH) Family
*1.A.69 The Heteromeric Odorant Receptor Channel (HORC) Family
*1.A.70 The Molecule Against Microbes A (MamA) Family 
*1.A.71 The Brain Acid-soluble Protein Channel (BASP1 Channel) Family 
*1.A.72 The Mer Superfamily
*1.A.73 The Colicin Lysis Protein (CLP) Family 
*1.A.74 The Mitsugumin 23 (MG23) Family
*1.A.75 The Mechanical Nociceptor, Piezo (Piezo) Family
*1.A.76 The Magnesium Transporter1 (MagT1) Family
*1.A.77 The Mg<sup>2+</sup>/Ca<sup>2+</sup> Uniporter (MCU) Family
*1.A.78 The K<sup>+</sup>-selective Channel in Endosomes and Lysosomes (KEL) Family
*1.A.79 The Cholesterol Uptake Protein (ChUP) or Double Stranded RNA Uptake Family
*1.A.80 The NS4a Viroporin (NS4a) Family
*1.A.81 The Low Affinity Ca<sup>2+</sup> Channel (LACC) Family
*1.A.82 The Hair Cell Mechanotransduction Channel (HCMC) Family
*1.A.83 The SV40 Virus Viroporin VP2 (SV40 VP2) Family
*1.A.84 The Calcium Homeostasis Modulator Ca<sup>2+</sup> Channel (CALHM-C) Family
*1.A.85 The Poliovirus 2B Viroporin (2B Viroporin) Family
*1.A.86 The Human Papilloma Virus type 16 (HPV16) L2 Viroporin (L2 Viroporin) Family
*1.A.87 The Mechanosensitive Calcium Channel (MCA) Family
*1.A.88 The Fungal Potassium Channel (F-Kch) Family
*1.A.89 The Human Coronavirus 229E Viroporin (229E Viroporin) Family
*1.A.90 The Human Metapneumovirus (HMPV) Viroporin (HMPV-Viroporin) Family
*1.A.91 The Cytoadherence-linked Asexual Protein 3.2 of Plasmodium falciparum (Clag3) Family
*1.A.92 The Reovirus Viroporin VP10 (RVP10) Family
*1.A.93 The Bluetongue Virus Non-Structural Protein 3 Viroporin (NS3) Family
*1.A.94 The Rotavirus Non-structural Glycoprotein 4 Viroporin (NSP4) Family
*1.A.95 The Ephemerovirus Viroporin (EVVP) Family
*1.A.96 The Human Polyoma Virus Viroporin (PVVP) Family 
*1.A.97 The Human Papillomavirus type 16 E5 Viroporin (HPV-E5) Family
*1.A.98 Human T-Lymphotropic Virus 1 P13 protein (HTLV1-P13) Family
*1.A.99 The Infectious Bronchitis Virus Envelope Small Membrane Protein E (IBV-E) Family 
*1.A.100 The Rhabdoviridae Putative Viroporin, U5 (RV-U5) Family
*1.A.101 The Peroxisomal Pore-forming Pex11 (Pex11) Family
*1.A.102 Influenza A viroporin PB1-F2 (PB1-F2) Family
*1.A.103 The Simian Virus 5 (Parainfluenza Virus 5) SH (SV5-SH) Family
*1.A.104 The Proposed Flagellar Biosynthesis Na<sup>+</sup> Channel, FlaH (FlaH) Family
*1.A.105 The Mixed Lineage Kinase Domain-like (MLKL) Family
*1.A.106 The Calcium Load-activated Calcium Channel (CLAC) Family 
*1.A.107 The Pore-forming Globin (Globin) Family

====1.B. [β-Barrel porins](/source/Porin_(protein)) and other outer membrane proteins====
* 1.B.1 [General bacterial porin family](/source/General_bacterial_porin_family)
* 1.B.2 [Chlamydial](/source/Chlamydia_(bacterium)) porin (CP) family
* 1.B.3 [Sugar porin](/source/Maltoporin) (SP) family
* 1.B.4 [Brucella-Rhizobium porin](/source/Brucella-Rhizobium_porin) (BRP) family
* 1.B.5 [Pseudomonas](/source/Pseudomonas) OprP porin (POP) family
* 1.B.6 [OmpA-OmpF porin (OOP) family](/source/OmpA-like_transmembrane_domain)
* 1.B.7 Rhodobacter PorCa porin (RPP) family
* 1.B.8 [Mitochondrial and plastid porin (MPP) family](/source/Voltage-dependent_anion_channel)
* 1.B.9 [FadL outer membrane protein (FadL) family](/source/FadL_outer_membrane_protein_transport_family)
* 1.B.10 [Nucleoside-specific channel-forming outer membrane porin (Tsx) family](/source/Nucleoside-specific_porin)
* 1.B.11 Outer membrane fimbrial usher porin (FUP) family
* 1.B.12 [Autotransporter-1](/source/Autotransporter_domain) (AT-1) family
* 1.B.13 [Alginate export porin](/source/Alginate_export_porin) (AEP) family
* 1.B.14 [Outer membrane receptor (OMR) family](/source/Outer_Membrane_Receptor)
* 1.B.15 Raffinose porin (RafY) family
* 1.B.16 Short chain amide and urea porin (SAP) family
* 1.B.17 [Outer membrane factor (OMF) family](/source/Outer_membrane_efflux_proteins)
* 1.B.18 [Outer membrane auxiliary (OMA) protein family](/source/Outer_membrane_polysaccharide_transporter)
* 1.B.19 Glucose-selective OprB porin (OprB) family
* 1.B.20 Two-partner secretion (TPS) family
* 1.B.21 [OmpG porin (OmpG) family](/source/Outer_membrane_protein_G)
* 1.B.22 Outer bacterial membrane secretin (secretin) family
* 1.B.23 Cyanobacterial porin (CBP) family
* 1.B.24 [Mycobacterial porin](/source/Mycobacterial_porin)
* 1.B.25 [Outer membrane porin (Opr) family](/source/Outer_membrane_porin_D)
* 1.B.26 Cyclodextrin porin (CDP) family
* 1.B.31 [Campylobacter jejuni](/source/Campylobacter_jejuni) major outer membrane porin (MomP) family
* 1.B.32 Fusobacterial outer membrane porin (FomP) family
* 1.B.33 Outer membrane protein insertion porin (Bam complex) (OmpIP) family
* 1.B.34 [Corynebacterial porins](/source/Corynebacterial_porin_B)
* 1.B.35 [Oligogalacturonate-specific porin (KdgM) family](/source/Oligogalacturonate-specific_porin)
* 1.B.39 [Bacterial porin, OmpW (OmpW) family](/source/Outer_membrane_protein_W_family)
* 1.B.42 Outer membrane lipopolysaccharide export porin (LPS-EP) family
* 1.B.43 Coxiella porin P1 (CPP1) family
* 1.B.44 Probable protein translocating porphyromonas gingivalis porin (PorT) family
* 1.B.49 Anaplasma P44 (A-P44) porin family
* 1.B.48 Curli-like transporters
* 1.B.54 [Intimin](/source/Intimin)/Invasin (Int/Inv) or [Autotransporter-3](/source/Autotransporter_domain) family
* 1.B.55 Poly-acetyl-D-glucosamine porin (PgaA) family
* 1.B.57 Legionella major-outer membrane protein (LM-OMP) family
* 1.B.60 Omp50 porin (Omp50 Porin) family
* 1.B.61 Delta-proteobacterial porin (Delta-porin) family
* 1.B.62 Putative bacterial porin (PBP) family
* 1.B.66 Putative beta-barrel porin-2 (BBP2) family
* 1.B.67 Putative beta barrel porin-4 (BBP4) family
* 1.B.68 Putative beta barrel porin-5 (BBP5) superfamily
* 1.B.70 Outer membrane channel (OMC) family
* 1.B.71 Proteobacterial/verrucomicrobial porin (PVP) family
* 1.B.72 Protochlamydial outer membrane porin (PomS/T) family
* 1.B.73 Capsule biogenesis/assembly (CBA) family
* 1.B.78 DUF3374 electron transport-associated porin (ETPorin) family

====1.C [Pore-forming toxin](/source/Pore-forming_toxin)s (proteins and peptides)====
* 1.C.3 α-[Hemolysin](/source/Hemolysin) (αHL) family
* 1.C.4 [Aerolysin](/source/Aerolysin) family
* 1.C.5 [ε-toxin](/source/%CE%B5-toxin) family
* 1.C.11 [RTX-toxin superfamily](/source/RTX_toxin)
* 1.C.12 [Membrane attack complex/perforin superfamily](/source/MACPF)
* 1.C.13 [Leukocidin](/source/Leukocidin) family
* 1.C.14 [Cytohemolysin](/source/Cytohemolysin) (CHL) family
* 1.C.39 [Thiol-activated cholesterol-dependent cytolysin family](/source/Cholesterol-dependent_cytolysin)
* 1.C.43 [Lysenin](/source/Lysenin) family
* 1.C.56 [''Pseudomonas syringae'' HrpZ cation channel family](/source/HrpZ_Family)
* 1.C.57 [Clostridial cytotoxin family](/source/Clostridial_Cytotoxin_family)
*1.C.58 [The Microcin E492/C24 (Microcin E492) Family](/source/Microcin)
* 1.C.74 [Snake cytotoxin](/source/Snake_venom) (SCT) family
* 1.C.97 [Pleurotolysin pore-forming family](/source/Pleurotolysin)

====1.D Non-ribosomally synthesized channels====
* 1.D.1 The [Gramicidin A](/source/Gramicidin_A) Channel Family
* 1.D.2 The Channel-forming [Syringomycin](/source/Syringomycin_E) Family
* 1.D.3 The Channel-Forming Syringopeptin Family
* 1.D.4 The Tolaasin Channel-forming Family
* 1.D.5 The [Alamethicin](/source/Alamethicin) or [Peptaibol](/source/Peptaibol) Antibiotic Channel-forming Family
* 1.D.6 The Complexed Poly 3-Hydroxybutyrate Ca<sup>2+</sup> Channel (cPHB-CC) Family
* 1.D.7 The Beticolin Family
* 1.D.8 The [Saponin](/source/Saponin) Family
* 1.D.9 The [Polyglutamine](/source/Polyglutamine) Ion Channel (PG-IC) Family
* 1.D.10 The [Ceramide](/source/Ceramide)-forming Channel Family
* 1.D.11 The [Surfactin](/source/Surfactin) Family
* 1.D.12 The Beauvericin (Beauvericin) Family
* 1.D.13 DNA-delivery Amphipathic Peptide Antibiotics (DAPA)
* 1.D.14 The Synthetic Leu/Ser Amphipathic Channel-forming Peptide (l/S-SCP) Family
* 1.D.15 [The Daptomycin (Daptomycin) Family](/source/Daptomycin)
* 1.D.16 The Synthetic Amphipathic Pore-forming Heptapeptide (SAPH) Family
* 1.D.17 Combinatorially-designed, Pore-forming, β-sheet Peptide Family
* 1.D.18 The Pore-forming Guanosine-Bile Acid Conjugate Family
* 1.D.19 Ca<sup>2+</sup> Channel-forming Drug, [Digitoxin](/source/Digitoxin) Family
* 1.D.20 The Pore-forming Polyene Macrolide Antibiotic/fungal Agent (PMAA) Family
* 1.D.21 The Lipid Nanopore (LipNP) Family
* 1.D.22 The Proton-Translocating Carotenoid Pigment, [Zeaxanthin](/source/Zeaxanthin) Family
* 1.D.23 Phenylene Ethynylene Pore-forming Antimicrobial (PEPA) Family
* 1.D.24 The Marine Sponge Polytheonamide B (pTB) Family
* 1.D.25 The Arylamine Foldamer (AAF) Family
* 1.D.26 The Dihydrodehydrodiconiferyl alcohol 9'-O-β-D-glucoside (DDDC9G) Family
* 1.D.27 The Thiourea isosteres Family
* 1.D.28 The Lipopeptaibol Family
* 1.D.29 The Macrocyclic Oligocholate Family
* 1.D.30 The Artificial Hydrazide-appended pillar[5]arene Channels (HAPA-C) Family
* 1.D.31 The [Amphotericin B](/source/Amphotericin_B) Family
* 1.D.32 The Pore-forming [Novicidin](/source/Novicidin) Family
* 1.D.33 The Channel-forming [Polytheonamide B](/source/Polytheonamide_B) Family
* 1.D.34 The Channel-forming Oligoester Bolaamphiphiles
* 1.D.35 The Pore-forming cyclic [Lipodepsipeptide](/source/Lipodepsipeptide) Family
* 1.D.36 The [Oligobornene](/source/Oligobornene) Ion Channel Family
* 1.D.37 The [Hibicuslide C](/source/Hibicuslide_C) Family
* 1.D.38 The Cyclic Peptide Nanotube (cPepNT) Family
* 1.D.39 The Light-controlled Azobenzene-based Amphiphilic Molecular Ion Channel (AAM-IC) Family
* 1.D.40 The Protein-induced Lipid Toroidal Pore Family
* 1.D.41 The Sprotetonate-type Ionophore (Spirohexanolide) Family
* 1.D.42 The Phe-Arg Tripeptide-Pillar[5]Arene Channel (TPPA-C) Family
* 1.D.43 The Triazole-tailored Guanosine Dinucleoside Channel (TT-GDN-C) Family
* 1.D.44 The Synthetic Ion Channel with Redox-active Ferrocene (ICRF) Family
* 1.D.45 The Sonoporation and Electroporation Membrane Pore (SEMP) Family
* 1.D.46 The DNA Nanopore (DnaNP) Family
* 1.D.47 The Pore-forming Synthetic Cyclic Peptide (PSCP) Family
* 1.D.48 The Pore-forming [Syringomycin E](/source/Syringomycin_E) Family
* 1.D.49 The Transmembrane Carotenoid Radical Channel (CRC) Family
* 1.D.50 The Amphiphilic bis-Catechol Anion Transporter (AC-AT) Family
* 1.D.51 The Protein Nanopore (ProNP) Family
* 1.D.52 The Aromatic Oligoamide Macrocycle Nanopore (OmnNP) Family
* 1.D.53 The alpha, gamma-Peptide Nanotube (a,gPepNT) Family
* 1.D.54 The potassium-selective Hexyl-Benzoureido-15-Crown-5-Ether Ion Channel (HBEC) Family
* 1.D.55 The Porphyrin-based Nanopore (PorNP) Family
* 1.D.56 The Alpha-Aminoisobutyrate (Aib) Oligomeric Nanopore (AibNP) Family
* 1.D.57 The Lipid Electro-Pore (LEP) Family
* 1.D.58 The Anion Transporting Prodigiosene (Prodigiosene) Family
* 1.D.59 The Anion Transporting Perenosin (Perenosin) Family
* 1.D.60 The Alpha,Gamma-Cyclic Peptide (AGCP) Family
* 1.D.61 The Anionophoric {{Chem name|2,6-Bis(Benzimidazol-2-yl)Pyridine}} (ABBP) Family
* 1.D.62 The Bis-Triazolyl DiGuanosine Derivative Channel-forming (TDG) Family
* 1.D.63 The Peptide-based Nanopore (PepNP) Family
* 1.D.64 The Carbon Nanotube (CarNT) Family
* 1.D.65 The Pore-forming Amphidinol (Amphidinol) Family
* 1.D.66 The Helical Macromolecule Nanopore (HmmNP) Family
* 1.D.67 The Crown Ether-modified Helical Peptide Ion Channel (CEHP) Family
* 1.D.68 The Pore-forming Pleuronic Block Polymer (PPBP) Family
* 1.D.69 The Conical Nanopore (ConNP) Family
* 1.D.70 The Metallic (Au/Ag/Pt/graphene) Nanopore (MetNP) Family
* 1.D.71 The Synthetic TP359 Peptide (TP359) Family
* 1.D.72 The Chloride Carrier Triazine-based Tripodal Receptor (CCTTR) Family
* 1.D.73 The Mesoporous Silica Nanopore (SilNP) Family
* 1.D.74 The Stimulus-responsive Synthetic Rigid p-Octiphenyl Stave Pore (SSROP) Family

====1.E [Holin](/source/Holin)s====
{{main|Holins}}

====1.F [Vesicle fusion](/source/Vesicle_fusion) pores====
* 1.F.1 The Synaptosomal Vesicle Fusion Pore (SVF-Pore) Family
* 1.F.2 The Octameric Exocyst (Exocyst) Family

====1.G [Viral fusion](/source/Viral_protein) pores====
* 1.G.1 The Viral Pore-forming Membrane Fusion Protein-1 (VMFP1) Family
* 1.G.2 The Viral Pore-forming Membrane Fusion Protein-2 (VMFP2) Family
* 1.G.3 The Viral Pore-forming Membrane Fusion Protein-3 (VMFP3) Family
* 1.G.4 The Viral Pore-forming Membrane Fusion Protein-4 (VMFP4) Family
* 1.G.5 The Viral Pore-forming Membrane Fusion Protein-5 (VMFP5) Family
* 1.G.6 The Hepadnaviral S Fusion Protein (HBV-S Protein) Family
* 1.G.7 The Reovirus FAST Fusion Protein (R-FAST) Family
* 1.G.8 The Arenavirus Fusion Protein (AV-FP) Family
* 1.G.9 The Syncytin (Syncytin) Family
* 1.G.10 The Herpes Simplex Virus Membrane Fusion Complex (HSV-MFC) Family
* 1.G.11 Poxvirus Cell Entry Protein Complex (PEP-C) Family
* 1.G.12 The Avian Leukosis Virus gp95 Fusion Protein (ALV-gp95) Family
* 1.G.13 The Orthoreovirus Fusion-associated Small Transmembrane (FAST) Family
* 1.G.14 The Influenza Virus Hemagglutinin/Fusion Pore-forming Protein (Influenza-H/FPP) Family
* 1.G.15 The Autographa californica Nuclear Polyhedrosis Virus Major Envelope Glycoprotein GP64 (GP64) Family
* 1.G.16 The Human Immunodeficiency Virus Type 1 (HIV-1) Fusion Peptide (HIV-FP) Family
* 1.G.17 The Bovine Leukemia Virus Envelop Glycoprotein (BLV-Env) Family
* 1.G.18 The SARS-CoV Fusion Peptide in the Spike Glycoprotein Precursor (SARS-FP) Family
* 1.G.19 The Rotavirus Pore-forming Membrane Fusion Complex (Rotavirus MFC) Family
* 1.G.20 The Hantavirus Gc Envelope Fusion Glycoprotein (Gc-EFG) Family
* 1.G.21 The Epstein Barr Virus (Human Herpes Virus 4) Gp42 (Gp42) Family
* 1.G.22 The Cytomegalovirus (Human Herpesvirus 5) Glycoprotein gO (gO) Family

====1.H [Paracellular channel](/source/Paracellular_channel)s====
* 1.H.1 The [Claudin](/source/Claudin) Tight Junction (Claudin1) Family
* 1.H.2 The Invertebrate PMP22-Claudin (Claudin2) Family

====1.I [Membrane-bound channel](/source/Membrane-bound_channel)s====
* 1.I.1 [Nuclear pore complex](/source/Nuclear_pore_complex) family, including [karyopherin](/source/karyopherin)s
* 1.I.2 Plant [plasmodesmata](/source/plasmodesmata) family

===2. Electrochemical potential-driven transporters===

====2.A Porters ([uniporter](/source/uniporter)s, [symporter](/source/symporter)s, [antiporter](/source/antiporter)s)====
{{see also|Amino acid transporter}}

*2.A.1 [Major Facilitator superfamily](/source/Major_facilitator_superfamily) (MFS), see also [Lactose permease](/source/Lactose_permease), [Phosphate permease](/source/Phosphate_permease) and [Glucose transporter](/source/Glucose_transporter)
*2.A.2 [The Glycoside-Pentoside-Hexuronide (GPH):Cation Symporter Family](/source/Glycoside-pentoside-hexuronide%3Acation_symporter_family)
*2.A.3 [The Amino Acid-Polyamine-Organocation (APC) Family](/source/APC_superfamily)
*2.A.4 [Cation diffusion facilitator](/source/Cation_diffusion_facilitator) (CDF) Family
*2.A.5 [Zinc (Zn<sup>2+</sup>)-Iron (Fe<sup>2+</sup>) Permease](/source/Ferroportin) Family
*2.A.6 [Resistance-Nodulation-Cell Division Superfamily](/source/Resistance-nodulation-cell_division_superfamily), see also [SecDF protein-export membrane protein](/source/SecDF_protein-export_membrane_protein)
*2.A.7 The [Drug/Metabolite Transporter](/source/Small_multidrug_resistance_protein) (DMT) Superfamily
*2.A.8 The Gluconate:H<sup>+</sup> Symporter (GntP) Family
*2.A.9 The Membrane Protein Insertase (YidC/Alb3/Oxa1) Family
*2.A.10 The 2-Keto-3-Deoxygluconate Transporter (KdgT) Family
*2.A.11 The Citrate-Mg<sup>2+</sup>:H<sup>+</sup> (CitM) Citrate-Ca<sup>2+</sup>:H<sup>+</sup> (CitH) Symporter (CitMHS) Family
*2.A.12 [ATP:ADP Antiporter Family](/source/ATP%3AADP_antiporter_family)
*2.A.13 The C4-Dicarboxylate Uptake (Dcu) Family
*2.A.14 [Lactate Permease Family](/source/Lactate_permease_family)
*2.A.15 [The Betaine/Carnitine/Choline Transporter (BCCT) Family](/source/Betaine_transporter)
*2.A.16 [Tellurite-resistance/Dicarboxylate Transporter](/source/Tellurite-resistance%2Fdicarboxylate_transporter) Family
*2.A.17 [Proton-dependent Oligopeptide Transporter Family](/source/Proton-dependent_oligopeptide_transporter)
*2.A.18 The Amino Acid/Auxin Permease (AAAP) Family
*2.A.19 The Ca<sup>2+</sup>:Cation Antiporter (CaCA) Family
*2.A.20 The Inorganic Phosphate Transporter (PiT) Family
*2.A.21 [Solute:Sodium Symporter Family](/source/Sodium-solute_symporter)
*2.A.22 The [Neurotransmitter:Sodium Symporter](/source/Neurotransmitter_sodium_symporter) Family
*2.A.23 The Dicarboxylate/Amino Acid:Cation (Na<sup>+</sup> or H<sup>+</sup>) Symporter (DAACS) Family
*2.A.24 The 2-Hydroxycarboxylate Transporter (2-HCT) Family
*2.A.25 [Alanine or Glycine:Cation Symporter](/source/AGCS_family) (AGCS) Family
*2.A.26 The Branched Chain Amino Acid:Cation Symporter (LIVCS) Family
*2.A.27 The Glutamate:Na<sup>+</sup> Symporter (ESS) Family
*2.A.28 [Bile Acid:Na<sup>+</sup> Symporter](/source/Bile_acid%3Asodium_symporter) Family
*2.A.29 [Mitochondrial carrier](/source/Mitochondrial_carrier) Family
*2.A.30 [Cation-Chloride Cotransporter](/source/Chloride_potassium_symporter) (CCC) Family
*2.A.31 [Anion Exchanger Family](/source/Anion_exchanger_family)
*2.A.32 The Silicon Transporter (Sit) Family
*2.A.33 [NhaA Na<sup>+</sup>:H<sup>+</sup> Antiporter](/source/Sodium-proton_antiporter) (NhaA) Family
*2.A.34 The NhaB Na<sup>+</sup>:H<sup>+</sup> Antiporter (NhaB) Family
*2.A.35 The NhaC Na<sup>+</sup>:H<sup>+</sup> Antiporter (NhaC) Family
*2.A.36 [Monovalent Cation:Proton Antiporter-1](/source/Monovalent_cation%3Aproton_antiporter-1) (CPA1) Family
*2.A.37 [Monovalent Cation:Proton Antiporter-2](/source/Monovalent_cation%3Aproton_antiporter-2) (CPA2) Family
*2.A.38 [K<sup>+</sup> Transporter (Trk)](/source/Potassium_transporter_family) Family
*2.A.39 [Nucleobase:Cation Symporter-1](/source/Nucleobase_cation_symporter-1) (NCS1) Family
*2.A.40 [Nucleobase:Cation Symporter-2](/source/Nucleobase_cation_symporter-2) (NCS2) Family
*2.A.41 The Concentrative Nucleoside Transporter (CNT) Family
*2.A.42 The Hydroxy/Aromatic Amino Acid Permease (HAAAP) Family
*2.A.43 The Lysosomal Cystine Transporter (LCT) Family
*2.A.45 [Arsenite-Antimonite Efflux Family](/source/Arsenite-antimonite_transporter)
*2.A.46 The Benzoate:H<sup>+</sup> Symporter (BenE) Family
*2.A.47 [Divalent Anion:Na<sup>+</sup> Symporter](/source/Divalent_anion%E2%80%93sodium_symporter) (DASS) Family
*2.A.48 The Reduced Folate Carrier (RFC) Family
*2.A.49 [Chloride Carrier/Channel](/source/Chloride_channel) (ClC) Family
*2.A.50 The Glycerol Uptake (GUP) Family
*2.A.51 The Chromate Ion Transporter (CHR) Family
*2.A.52 The Ni<sup>2+</sup>-Co<sup>2+</sup> Transporter (NiCoT) Family
*2.A.53 [Sulfate permease](/source/Sulfate_permease) (SulP) Family
*2.A.54 The Mitochondrial Tricarboxylate Carrier (MTC) Family
*2.A.55 [The Metal Ion (Mn<sup>2+</sup>-iron) Transporter](/source/Natural_Resistance-Associated_Macrophage_Proteins) (Nramp) Family
*2.A.56 The Tripartite ATP-independent Periplasmic Transporter (TRAP-T) Family
*2.A.57 The Equilibrative Nucleoside Transporter (ENT) Family
*2.A.58 The Phosphate:Na<sup>+</sup> Symporter (PNaS) Family
*2.A.59 The Arsenical Resistance-3 (ACR3) Family
*2.A.60 [Organo Anion Transporter](/source/Organo_anion_transporter_family) (OAT) Family
*2.A.61 The C4-dicarboxylate Uptake C (DcuC) Family
*2.A.62 The NhaD Na<sup>+</sup>:H<sup>+</sup> Antiporter (NhaD) Family
*2.A.63 [The Monovalent Cation (K<sup>+</sup> or Na<sup>+</sup>):Proton Antiporter-3](/source/Monovalent_cation%3Aproton_antiporter-3) (CPA3) Family
*2.A.64 [Twin Arginine Targeting (Tat) Family](/source/Twin-arginine_translocation_pathway)
*2.A.65 The Bilirubin Transporter (BRT) Family
*2.A.66 The Multidrug/Oligosaccharidyl-lipid/Polysaccharide (MOP) Flippase Superfamily
*2.A.67 The Oligopeptide Transporter (OPT) Family
*2.A.68 The p-Aminobenzoyl-glutamate Transporter (AbgT) Family
*2.A.69 The Auxin Efflux Carrier (AEC) Family
*2.A.70 The Malonate:Na<sup>+</sup> Symporter (MSS) Family
*2.A.71 The Folate-Biopterin Transporter (FBT) Family
*2.A.72 The K<sup>+</sup> Uptake Permease (KUP) Family
*2.A.73 The Short Chain Fatty Acid Uptake (AtoE) Family
*2.A.74 The 4 TMS Multidrug Endosomal Transporter (MET) Family
*2.A.75 The L-Lysine Exporter (LysE) Family
*2.A.76 The Resistance to Homoserine/Threonine (RhtB) Family
*2.A.77 The Cadmium Resistance (CadD) Family
*2.A.78 The Branched Chain Amino Acid Exporter (LIV-E) Family
*2.A.79 The Threonine/Serine Exporter (ThrE) Family
*2.A.80 The Tricarboxylate Transporter (TTT) Family
*2.A.81 The Aspartate:Alanine Exchanger (AAEx) Family
*2.A.82 The Organic Solute Transporter (OST) Family
*2.A.83 The Na<sup>+</sup>-dependent Bicarbonate Transporter (SBT) Family
*2.A.84 The Chloroplast Maltose Exporter (MEX) Family
*2.A.85 The Aromatic Acid Exporter (ArAE) Family
*2.A.86 The Autoinducer-2 Exporter (AI-2E) Family (Formerly the PerM Family, TC #9.B.22)
*2.A.87 The Prokaryotic Riboflavin Transporter (P-RFT) Family
*2.A.88 Vitamin Uptake Transporter (VUT or ECF) Family
*2.A.89 The Vacuolar Iron Transporter (VIT) Family
*2.A.90 Vitamin A Receptor/Transporter ([STRA6](/source/Receptor_for_retinol_uptake_STRA6)) Family
*2.A.91 Mitochondrial tRNA Import Complex (M-RIC) (Formerly 9.C.8)
*2.A.92 The Choline Transporter-like (CTL) Family
*2.A.94 The Phosphate Permease (Pho1) Family
*2.A.95 The 6TMS Neutral Amino Acid Transporter (NAAT) Family
*2.A.96 The Acetate Uptake Transporter (AceTr) Family
*2.A.97 The Mitochondrial Inner Membrane K<sup>+</sup>/H<sup>+</sup> and Ca<sup>2+</sup>/H<sup>+</sup> Exchanger (LetM1) Family
*2.A.98 The Putative Sulfate Exporter (PSE) Family
*2.A.99 The 6TMS Ni<sup>2+</sup> uptake transporter (HupE-UreJ) Family
*2.A.100 The Ferroportin (Fpn) Family
*2.A.101 The Malonate Uptake (MatC) Family (Formerly UIT1)
*2.A.102 The 4-Toluene Sulfonate Uptake Permease (TSUP) Family
*2.A.103 The Bacterial Murein Precursor Exporter (MPE) Family
*2.A.104 The L-Alanine Exporter (AlaE) Family
*2.A.105 The Mitochondrial Pyruvate Carrier (MPC) Family
*2.A.106 The Ca<sup>2+</sup>:H<sup>+</sup> Antiporter-2 (CaCA2) Family
*2.A.107 The MntP Mn<sup>2+</sup> Exporter (MntP) Family
*2.A.108 The Iron/Lead Transporter (ILT) Family
*2.A.109 The Tellurium Ion Resistance (TerC) Family
*2.A.110 The Heme Transporter, heme-responsive gene protein (HRG) Family
*2.A.111 The Na<sup>+</sup>/H<sup>+</sup> Antiporter-E (NhaE) Family
*2.A.112 The KX Blood-group Antigen (KXA) Family
*2.A.113 The Nickel/cobalt Transporter (NicO) Family
*2.A.114 The Putative Peptide Transporter Carbon Starvation CstA (CstA) Family
*2.A.115 The Novobiocin Exporter (NbcE) Family
*2.A.116 The Peptidoglycolipid Addressing Protein (GAP) Family
*2.A.117 The Chlorhexadine Exporter (CHX) family
*2.A.118 The Basic Amino Acid Antiporter (ArcD) Family
*2.A.119 The Organo-Arsenical Exporter (ArsP) Family
*2.A.120 The Putative Amino Acid Permease (PAAP) Family
*2.A.121 The Sulfate Transporter (CysZ) Family
*2.A.122 The LrgB/CidB holin-like auxiliary protein (LrgB/CidB) Family
*2.A.123 The Sweet; PQ-loop; Saliva; MtN3 (Sweet) Family
*2.A.124 The Lysine Exporter (LysO) Family
*2.A.125 The Eukaryotic Riboflavin Transporter (E-RFT) Family
*2.A.126 The Fatty Acid Exporter (FAX) Family
*2.A.127 Enterobacterial Cardiolipin Transporter (CLT) Family

====2.B Nonribosomally synthesized porters====
*2.B.1 The [Valinomycin](/source/Valinomycin) Carrier Family
*2.B.2 The [Monensin](/source/Monensin) Family
*2.B.3 The [Nigericin](/source/Nigericin) Family
*2.B.4 The [Macrotetrolide](/source/Macrotetrolide) Antibiotic (MA) Family
*2.B.5 The Macrocyclic Polyether (MP) Family
*2.B.6 The [Ionomycin](/source/Ionomycin) Family
*2.B.7 The Transmembrane α-helical Peptide Phospholipid Translocation (TMP-PLT) Family
*2.B.8 The [Bafilomycin](/source/Bafilomycin) A1 (Bafilomycin) Family
*2.B.9 The [Cell Penetrating Peptide](/source/Cell_Penetrating_Peptide) (CPP) Functional Family
*2.B.10 The Synthetic CPP, [Transportan](/source/Transportan) Family 
*2.B.11 The [Calcimycin](/source/Calcimycin) or A23187 Carrier-type Ionophore Family
*2.B.12 The [Salinomycin](/source/Salinomycin) Family
*2.B.13 The Tetrapyrrolic Macrocyclic Anion Antiporter (TPMC-AA) Family
*2.B.14 The Lasalocid A or X-537A Ionophore (Lasalocid) Family
*2.B.15 The Tris-thiourea Tripodal-based Chloride Carrier (TTT-CC) Family 
*2.B.16 The Halogen-bond-containing Compound Anion Carrier (HCAC) Family
*2.B.17 The Isophthalaminde Derivative H<sup>+</sup>:Cl<sup>−</sup> Co-transporter (IDC) Family
*2.B.18 The Pyridine-2,6-Dicarboxamine Derivative (PDCA) H+:Cl<sup>−</sup> Co-transporter Family 
*2.B.19 The Calix(4)pyrrole Derivative (C4P) Family
*2.B.20 The Prodigiosin (Prodigiosin) Chloride/Bicarbonate Exchanger Family
*2.B.21 The ortho-Phenylenediamine-bis-Urea Derivative Anion Transporter (oPDA-U) Family 
*2.B.22 The Imidazolium-functionalized Anion Transporter (IAT) Family
*2.B.23 The Homotetrameric Transmembrane Zn<sup>2+</sup>/Co<sup>2+</sup>:Proton Synthetic Antiporter, Rocker (Rocker) Family
*2.B.24 The {{Chem name|2,6-Bis(benzimidazol-2-yl)pyridine}} Anion Carrier (BBP-AC) Family
*2.B.25 The Peptide-mediated Lipid Flip-Flop (PLFF) Family
*2.B.26 The {{Not a typo|Bis(imidazolyl)-functionalized}} {{Not a typo|Bis(Choloyl)}} Conjugate (BIBCC) Family
*2.B.27 The Tris-Urea Anion Transporter Family
*2.B.29 The Anionophoric Marine Alkaloid [Tambjamine](/source/Tambjamine) Family

====2.C Ion-gradient-driven energizers====
*2.C.1 The TonB-ExbB-ExbD/TolA-TolQ-TolR (TonB) Family of Auxiliary Proteins for Energization of Outer Membrane Receptor (OMR)-mediated Active Transport

===3. [Primary active transport](/source/Primary_active_transport)ers===

====3.A. P-P-bond hydrolysis-driven transporters====
*3.A.1 [ABC transporter](/source/ABC_transporter)s including BtuCD, molybdate uptake transporter, [Cystic fibrosis transmembrane conductance regulator](/source/Cystic_fibrosis_transmembrane_conductance_regulator) and others
*3.A.2 The H<sup>+</sup>- or Na<sup>+</sup>-translocating [F-type ATPase](/source/F-type_ATPase), [V-type ATPase](/source/V-type_ATPase) and A-type ATPase superfamily
*3.A.3 [The P-type ATPase](/source/P-type_ATPase) Superfamily
*3.A.4 [The Arsenite-Antimonite efflux](/source/ArsB_and_ArsAB_transporters) family
*3.A.5 [General secretory pathway](/source/SecY_protein) (Sec) [translocon](/source/translocon) (preprotein translocase SecY)
*3.A.6 The Type III (Virulence-related) Secretory Pathway (IIISP) Family
*3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
*3.A.8 The Mitochondrial Protein Translocase (MPT) Family
*3.A.9 The Chloroplast Envelope Protein Translocase (CEPT or Tic-Toc) Family
*3.A.10 [H<sup>+</sup>, Na<sup>+</sup>-translocating Pyrophosphatase](/source/H%2B%2C_Na%2B-translocating_pyrophosphatase_family) family
*3.A.11 The Bacterial Competence-related DNA Transformation Transporter (DNA-T) Family
*3.A.12 The Septal DNA Translocator (S-DNA-T) Family
*3.A.13 The Filamentous Phage Exporter (FPhE) Family
*3.A.14 The Fimbrilin/Protein Exporter (FPE) Family
*3.A.15 The Outer Membrane Protein Secreting Main Terminal Branch (MTB) Family
*3.A.16 The Endoplasmic Reticular Retrotranslocon (ER-RT) Family
*3.A.17 The Phage T7 Injectisome (T7 Injectisome) Family
*3.A.18 The Nuclear mRNA Exporter (mRNA-E) Family
*3.A.19 The TMS Recognition/Insertion Complex (TRC) Family
*3.A.20 The Peroxisomal Protein Importer (PPI) Family
*3.A.21 The C-terminal Tail-Anchored Membrane Protein Biogenesis/ Insertion Complex (TAMP-B) Family
*3.A.22 The Transcription-coupled TREX/TAP Nuclear mRNA Export Complex (TREX) Family
*3.A.23 The Type VI Symbiosis/Virulence Secretory Pathway (VISP) Family
*3.A.24 Type VII or ESX Protein Secretion System (T7SS) Family
*3.A.25 The Symbiont-specific ERAD-like Machinery (SELMA) Family
*3.A.26 The Plasmodium Translocon of Exported proteins (PTEX) Family

====3.B Decarboxylation-driven transporters====
*3.B.1 The Na<sup>+</sup>-transporting Carboxylic Acid Decarboxylase (NaT-DC) Family

====3.C Methyltransfer-driven transporters====
*3.C.1 The Na<sup>+</sup> Transporting Methyltetrahydromethanopterin:Coenzyme M Methyltransferase (NaT-MMM) Family

====3.D. Oxidoreduction-driven transporters====
They include a number of transmembrane [cytochrome b](/source/cytochrome_b)-like proteins including [coenzyme Q - cytochrome c reductase](/source/coenzyme_Q_-_cytochrome_c_reductase) (cytochrome bc1 ); [cytochrome b6f complex](/source/cytochrome_b6f_complex); formate dehydrogenase, respiratory [nitrate reductase](/source/nitrate_reductase); [succinate - coenzyme Q reductase](/source/succinate_-_coenzyme_Q_reductase) (fumarate reductase); and [succinate dehydrogenase](/source/succinate_dehydrogenase).  See [electron transport chain](/source/electron_transport_chain).

*3.D.1 [The H<sup>+</sup> or Na<sup>+</sup>-translocating NADH Dehydrogenase](/source/NADH%3Aubiquinone_reductase_(H%2B-translocating)) ("complex I") family 
*3.D.2 The Proton-translocating Transhydrogenase (PTH) Family
*3.D.3 [The Proton-translocating Quinol:Cytochrome c Reductase](/source/Cytochrome_c_nitrite_reductase)) Superfamily
*3.D.4 [Proton-translocating Cytochrome Oxidase](/source/Cytochrome_c_oxidase) (COX) Superfamily
*3.D.5 The Na<sup>+</sup>-translocating NADH:Quinone Dehydrogenase (Na-NDH or NQR) Family
*3.D.6 The Putative Ion (H<sup>+</sup> or Na<sup>+</sup>)-translocating NADH:Ferredoxin Oxidoreductase (NFO or RNF) Family
*3.D.7 The H<sub>2</sub>:Heterodisulfide Oxidoreductase (HHO) Family
*3.D.8 The Na<sup>+</sup>- or H<sup>+</sup>-Pumping Formyl Methanofuran Dehydrogenase (FMF-DH) Family
*3.D.9 The H<sup>+</sup>-translocating F420H2 Dehydrogenase (F420H2DH) Family
*3.D.10 The Prokaryotic Succinate Dehydrogenase (SDH) Family

====3.E. Light absorption-driven transporters====
*[Bacteriorhodopsin](/source/Bacteriorhodopsin)-like proteins including [rhodopsin](/source/rhodopsin) (see also [opsin](/source/opsin))
*Bacterial [photosynthetic reaction centre](/source/photosynthetic_reaction_centre)s and [photosystem](/source/photosystem)s I and II
*[Light harvesting complex](/source/Light_harvesting_complex)es from [bacteria](/source/bacteria) and [chloroplasts](/source/chloroplasts)

===4. Group translocators===

====4.A Phosphotransfer-driven group translocators====
{{main|PTS-GFL superfamily}}

*4.A.1 [The PTS Glucose-Glucoside (Glc) Family](/source/The_PTS_glucose-glucoside_(Glc)_family)
*4.A.2 The PTS Fructose-Mannitol (Fru) Family
*4.A.3 The PTS Lactose-N,N'-Diacetylchitobiose-β-glucoside (Lac) Family
*4.A.4 The PTS Glucitol (Gut) Family
*4.A.5 The PTS Galactitol (Gat) Family
*4.A.6 [The PTS Mannose-Fructose-Sorbose (Man) Family](/source/PTS_Mannose-Fructose-Sorbose_Family)
*4.A.7 The PTS L-Ascorbate (L-Asc) Family

====4.B Nicotinamide ribonucleoside uptake transporters====
*4.B.1 The Nicotinamide Ribonucleoside (NR) Uptake Permease (PnuC) Family

====4.C Acyl CoA ligase-coupled transporters====
*4.C.1 The Proposed Fatty Acid Transporter (FAT) Family
*4.C.2 The Carnitine O-Acyl Transferase (CrAT) Family
*4.C.3 The Acyl-CoA Thioesterase (AcoT) Family

====4.D Polysaccharide Synthase/Exporters====
*4.D.1 The Putative Vectorial Glycosyl Polymerization (VGP) Family
*4.D.2 The Glycosyl Transferase 2 (GT2) Family
*4.D.3 The Glycan Glucosyl Transferase (OpgH) Family

====4.E. Vacuolar Polyphosphate Polymerase-catalyzed Group Translocators====
*4.E.1 The Vacuolar (Acidocalcisome) Polyphosphate Polymerase (V-PPP) Family

===5. Transport electron carriers===
====5.A Transmembrane 2-electron transfer carriers====
*5.A.1 The Disulfide Bond Oxidoreductase D (DsbD) Family
*5.A.2 The Disulfide Bond Oxidoreductase B (DsbB) Family
*5.A.3 The Prokaryotic Molybdopterin-containing Oxidoreductase (PMO) Family

====5.B Transmembrane 1-electron transfer carriers====
*5.B.1 The Phagocyte ([gp91phox](/source/gp91phox)) [NADPH Oxidase](/source/NADPH_oxidase) Family
*5.B.2 The Eukaryotic [Cytochrome b561](/source/Cytochrome_b561) (Cytb561) Family
*5.B.3 The Geobacter Nanowire Electron Transfer (G-NET) Family
*5.B.4 The Plant Photosystem I Supercomplex (PSI) Family
*5.B.5 The Extracellular Metal Oxido-Reductase (EMOR) Family
*5.B.6 The [Transmembrane Epithelial Antigen Protein-3](/source/STEAP3) Ferric Reductase (STEAP) Family
*5.B.7 The [YedZ (YedZ) Family](/source/YedZ_family)
*5.B.8 The Trans-Outer Membrane Electron Transfer Porin/Cytochrome Complex (ET-PCC) Family
*5.B.9 The Porin-Cytochrome c (Cyc2) Family

===8. Accessory factors involved in transport===

====8.A Auxiliary transport proteins====

====8.B Ribosomally synthesized protein/peptide toxins that target channels and carriers====

====8.C Non-ribosomally synthesized toxins that target channels and carriers====

===9. Incompletely characterized transport systems===

====9.A Recognized transporters of unknown biochemical mechanism====

====9.B Putative transport proteins====

====9.C Functionally characterized transporters lacking identified sequences====

==References==
{{reflist}}

==External links==
* [http://www.tcdb.org/ Transporter Classification Database]
* [http://www.chem.qmul.ac.uk/iubmb/mtp/ List] at qmul.ac.uk
* {{cite journal |vauthors=Saier MH, Tran CV, Barabote RD |title=TCDB: the Transporter Classification Database for membrane transport protein analyses and information |journal=Nucleic Acids Res. |volume=34 |issue=Database issue |pages=D181–6 |date=January 2006 |pmid=16381841 |pmc=1334385 |doi=10.1093/nar/gkj001 |url=}}
* {{cite journal |vauthors=Busch W, Saier MH |title=The transporter classification (TC) system, 2002 |journal=Crit. Rev. Biochem. Mol. Biol. |volume=37 |issue=5 |pages=287–337 |year=2002 |pmid=12449427 |doi= 10.1080/10409230290771528|s2cid=10558982 }}
* [http://www.guidetopharmacology.org/GRAC/ReceptorFamiliesForward?type=TRANSPORTER Classification of human transporters in pharmacology]

{{Ion channels}}
{{Pore-forming toxins}}
{{Non-ribosomally synthesized channels}}
{{Vesicular transport proteins}}
{{Membrane transport proteins}}
{{Nonribosomally synthesized porters}}
{{ABC transporters}}
{{Ion pumps}}
{{Oxidoreduction-driven transporters}}

Category:Biochemistry databases
Category:Transport proteins
Category:Transmembrane proteins
Category:Protein classification

---
Adapted from the Wikipedia article [Transporter Classification Database](https://en.wikipedia.org/wiki/Transporter_Classification_Database) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/Transporter_Classification_Database?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.
