# Tomes's process

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**Tomes's processes** (also called **Tomes processes**) are a [histologic](/source/Histology) landmark identified on an [ameloblast](/source/Ameloblast), cells involved in the production of [tooth enamel](/source/Tooth_enamel). During the synthesis of enamel, the ameloblast moves away from the [enamel](/source/Tooth_enamel), forming a projection surrounded by the developing enamel. Tomes's processes are those projections and give the ameloblast a "picket-fence" appearance under a [microscope](/source/Microscope).

They are located on the secretory, basal, end of the ameloblast.

[Terminal bar](/source/Terminal_bar_(histology)) apparatuses connect the Tomes's processes. [Tonofilaments](/source/Tonofilament) separate the developing enamel from the enamel organ. [Gap junctions](/source/Gap_junction) synchronize cell activation.

The body of the cell between the processes first deposits enamel, which will become the periphery of the enamel prisms, then the Tomes's process will infill the main body of the enamel prism. More than one ameloblast contributes to a single prism.

Tomes's processes are distinctly different from [Tomes's fibers](/source/Tomes's_fibers), which are odontoblastic processes that occupy dentinal tubules.

## See also

- [Tooth](/source/Tooth)
- [Tomes's fibers](/source/Tomes's_fibers)
- [John Tomes](/source/John_Tomes)

## References

- Cate, A. R. Ten. Oral Histology: development, structure, and function. 5th ed. 1998. ISBN 0-8151-2952-1.
- Ross, Michael H., Gordon I. Kaye, and Wojciech Pawlina. Histology: a text and atlas. 4th edition. 2003. ISBN 0-683-30242-6.

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