# Testosterone (patch)

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{{Short description|Medication}}
The '''testosterone patch''', brand name '''Intrinsa''' among others, was designed to treat [female sexual dysfunction](/source/female_sexual_dysfunction).

==Mechanism of action==
Testosterone patches works by releasing the hormone [testosterone](/source/testosterone_(medication)) through the skin into the bloodstream. In women, testosterone is naturally produced by the [ovaries](/source/ovaries) and the [adrenal](/source/adrenal) gland. However, levels of the hormone decline with age, sometimes more after [menopause](/source/menopause). Testosterone therapy is systemic and needs to be applied over a period of weeks or months to have an effect.<ref name=bw>[https://web.archive.org/web/20041028112855/http://www.businessweek.com/bwdaily/dnflash/oct2004/nf20041028_8091_db016.htm Can Intrinsa Be a Viagra for Women?] BusinessWeek, October 28, 2004. Retrieved June 22, 2007.</ref> P&G licensed the treatment to Watson Pharmaceuticals.<ref name=bw/>

==Approval==

The patch was granted a license from the [European Medicines Agency](/source/European_Medicines_Agency) in July, and is available on [Britain](/source/United_Kingdom)'s [National Health Service](/source/National_Health_Service) from March 2007.{{cn|date=June 2020}}

However, in December 2004 the [United States](/source/United_States) the 14-member [Food and Drug Administration](/source/Food_and_Drug_Administration_(United_States)) (FDA) advisory committee, plus voting consultants, for Reproductive Health Drugs unanimously rejected Procter and Gamble's fast-track request for Intrinsa citing concerns about [off-label use](/source/off-label_use).  In Canada, post-menopausal women have been able to obtain government-approved testosterone treatment since 2002. In Australia, post-menopausal women can use [Organon](/source/Organon_International) testosterone implants which have to be surgically inserted and last from three to six months.<ref name=about>[http://uspolitics.about.com/od/healthcare/a/Intrinsa_d03.htm FDA Panel Rejects Intrinsa] {{Webarchive|url=https://web.archive.org/web/20070905194204/http://uspolitics.about.com/od/healthcare/a/Intrinsa_d03.htm |date=2007-09-05 }} About.com Politics, December 2004. Retrieved 22 June 2007.</ref>

==See also==
* [List of androgens available in the United States](/source/List_of_androgens_available_in_the_United_States)
* [Bremelanotide](/source/Bremelanotide)
* [Flibanserin](/source/Flibanserin)
* [Melanotan II](/source/Melanotan_II)

==References==
{{Reflist}}

==External links==
* [http://www.intrinsa.com Procter and Gamble web page for Intrinsa].
* [https://web.archive.org/web/20071121134143/http://www.intrinsa.org/ Information on Intrinsa and User Forum]
* [http://news.bbc.co.uk/1/hi/health/6495211.stm Patch 'to boost female sex drive']
* [https://web.archive.org/web/20070927215546/http://www.thestreet.com/stocks/robertsteyer/10196841.html FDA Looks at P&G's Sex-Drive Drug]
* [https://www.usatoday.com/news/opinion/editorials/2004-11-22-berman_x.htm Women's sexual health deserves equal attention]

{{Sexual dysfunction pharmacotherapies}}
{{Androgens and antiandrogens}}
{{Androgen receptor modulators}}

Category:Androgens
Category:Female sexual dysfunction drugs
Category:Aphrodisiacs

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Adapted from the Wikipedia article [Testosterone (patch)](https://en.wikipedia.org/wiki/Testosterone_(patch)) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/Testosterone_(patch)?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.