# Subconjunctival injection

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**Subconjunctival injection** is a type of [periocular route of injection](/source/Periocular_injection) for ocular [drug administration](/source/Route_of_drug_administration) by administration of a medication either under the [conjunctiva](/source/Conjunctiva) or underneath the conjunctiva lining the [eyelid](/source/Eyelid).

Using the subconjunctival injection bypasses the fatty layers of the bulbous conjunctiva and putting medications adjacent to [sclera](/source/Sclera) that is permeable to water, this will increase the penetration of the water-soluble drug into the [eye](/source/Human_eye).[1]

This route is indicated for treatment of different lesions, such as in the [cornea](/source/Cornea), sclera, anterior [uvea](/source/Uvea) and [vitreous](/source/Vitreous_body).

[Antibiotics](/source/Antibiotics) and [corticosteroids](/source/Corticosteroids)[2] can be administered by this route.

## References

1. [Eye: drug administration - subconjunctival injection](https://www.vetstream.com/treat/equis/technique/eye-drug-administration-subconjunctival-injection)

1. Koff, Raphael; Rome, SOL; Kasper, Richard; Commons, Robert R.; Button, Richard; Starr, Paul (1950). ["Subconjunctival Injection of Cortisone in Iritis"](https://jamanetwork.com/journals/jama/article-abstract/306955). *Journal of the American Medical Association*. **144** (15): 1259. [doi:10.1001/jama.1950.62920150004009a](https://doi.org/10.1001/jama.1950.62920150004009a). [PMID 14778735](https://pubmed.ncbi.nlm.nih.gov/14778735)

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