# Sample preparation

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{{Short description|Treatment prior to chemical analysis}}
In [analytical chemistry](/source/analytical_chemistry), '''sample preparation''' (working-up) refers to the ways in which a sample is treated prior to its analyses. Preparation is a very important  step in most analytical techniques, because the techniques are often not responsive to the analyte in its [in-situ](/source/in-situ) form, or the results are distorted by interfering [species](/source/chemical_species). Sample preparation may involve [dissolution](/source/Solution_(chemistry)), [extraction](/source/Extraction_(chemistry)), [reaction](/source/chemical_reaction) with some chemical species, [pulverizing](/source/Powder_(substance)), treatment with a [chelating](/source/complex_(chemistry)) agent (e.g. [EDTA](/source/EDTA)), [masking](/source/masking_agent), [filtering](/source/Filter_(chemistry)), [dilution](/source/%3Awikt%3Adilution), [sub-sampling](/source/sub-sampling_(chemistry)) or many other techniques.
Treatment is done to prepare the sample into a form ready for analysis by specified analytical equipment.
Sample preparation could involve: crushing and dissolution, chemical digestion with acid or alkali, sample extraction, sample clean up  and sample pre-concentration.

==References==

*{{cite web
| title = Sample Preparation
| url = http://www.panalytical.com/index.cfm?pid=206
| accessdate = 2007-11-09}}

{{Analytical chemistry}}{{Authority control}}
{{analytical-chem-stub}}
Category:Analytical chemistry

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