# SEDLP

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> Markdown URL: https://mediated.wiki/source/SEDLP.md
> Source: https://en.wikipedia.org/wiki/SEDLP
> Source revision: 1351180374
> License: Creative Commons Attribution-ShareAlike 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/)

{{Short description|Pseudogene in the species Homo sapiens}}
{{Infobox_gene}}

'''Trafficking protein particle complex subunit 2''' is a [protein](/source/protein) that in humans is encoded by the ''TRAPPC2P1'' [gene](/source/gene).<ref name="entrez">{{cite web | title = Entrez Gene: SEDLP spondyloepiphyseal dysplasia, late, pseudogene| url = https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=10597}}</ref>

This gene has been described as a transcribed [retropseudogene](/source/retropseudogene) (or retro-xaptonuon) based on its structure which lacks most of the [introns](/source/introns) of SEDL and the detection of [transcripts](/source/primary_transcript) from this locus. Most retropseudogenes are thought to not express protein products. A protein product could potentially be encoded by this retropseudogene that would be identical to the protein product of the SEDL gene. However, it remains unclear whether this gene encodes a protein product or is a transcribed retropseudogene.<ref name="entrez">{{cite web | title = Entrez Gene: SEDLP spondyloepiphyseal dysplasia, late, pseudogene| url = https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=10597}}</ref>

==References==
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==Further reading==
{{refbegin | 2}}
*{{cite journal  | author=Sacher M |title=Membrane traffic fuses with cartilage development. |journal=FEBS Lett. |volume=550 |issue= 1–3 |pages= 1–4 |year= 2003 |pmid= 12935876 |doi=10.1016/S0014-5793(03)00854-8  |s2cid=7388750 |doi-access= |bibcode=2003FEBSL.550....1S }}
*{{cite journal   |vauthors=Gécz J, Hillman MA, Gedeon AK, etal |title=Gene structure and expression study of the SEDL gene for spondyloepiphyseal dysplasia tarda |journal=Genomics |volume=69 |issue= 2 |pages= 242–51 |year= 2001 |pmid= 11031107 |doi= 10.1006/geno.2000.6326 }}
*{{cite journal   |vauthors=Ghosh AK, Majumder M, Steele R, etal |title=A novel 16-kilodalton cellular protein physically interacts with and antagonizes the functional activity of c-myc promoter-binding protein 1 |journal=Mol. Cell. Biol. |volume=21 |issue= 2 |pages= 655–62 |year= 2001 |pmid= 11134351 |doi= 10.1128/MCB.21.2.655-662.2001  | pmc=86643 }}
*{{cite journal   |vauthors=Venter JC, Adams MD, Myers EW, etal |title=The sequence of the human genome |journal=Science |volume=291 |issue= 5507 |pages= 1304–51 |year= 2001 |pmid= 11181995 |doi= 10.1126/science.1058040 |bibcode=2001Sci...291.1304V |doi-access=  }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
*{{cite journal  | vauthors=Ghosh AK, Steele R, Ray RB |title=Modulation of human luteinizing hormone beta gene transcription by MIP-2A |journal=J. Biol. Chem. |volume=278 |issue= 26 |pages= 24033–8 |year= 2003 |pmid= 12700240 |doi= 10.1074/jbc.M211982200 |doi-access= free }}
*{{cite journal  | vauthors=Savarirayan R, Thompson E, Gécz J |title=Spondyloepiphyseal dysplasia tarda (SEDL, MIM #313400) |journal=Eur. J. Hum. Genet. |volume=11 |issue= 9 |pages= 639–42 |year= 2004 |pmid= 12939648 |doi= 10.1038/sj.ejhg.5201025 |doi-access= free }}
*{{cite journal  | vauthors=Gécz J, Shaw MA, Bellon JR, de Barros Lopes M |title=Human wild-type SEDL protein functionally complements yeast Trs20p but some naturally occurring SEDL mutants do not |journal=Gene |volume=320 |pages= 137–44 |year= 2004 |pmid= 14597397 |doi=10.1016/S0378-1119(03)00819-9  }}
*{{cite journal   |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |bibcode=2005Natur.437.1173R |s2cid=4427026 }}
{{refend}}

{{protein-stub}}

Category:Proteins

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Adapted from the Wikipedia article [SEDLP](https://en.wikipedia.org/wiki/SEDLP) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/SEDLP?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.