# Repoxygen

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> Source: https://en.wikipedia.org/wiki/Repoxygen
> Source revision: 1314608329
> License: Creative Commons Attribution-ShareAlike 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/)

**Repoxygen** was the tradename for a type of [gene therapy](/source/Gene_therapy) to produce [erythropoietin](/source/Erythropoietin) (EPO). It was under preclinical development by Oxford Biomedica as a possible treatment for [anaemia](/source/Anaemia) but was abandoned in 2003.[1]

The project became infamous when it was mentioned during the criminal trial of Thomas Springstein, a former track coach for some German athletes, who was found guilty of giving athletes [performance enhancing drugs](/source/Performance_enhancing_drugs) without their knowledge. An email in which Springstein attempted to obtain Repoxygen was read by a prosecutor, which led to a flurry of media coverage.[2]

The [World Anti-Doping Agency](/source/World_Anti-Doping_Agency) banned "gene doping" in 2003[2] and as of 2009 was researching detection methods for substances such as repoxygen.[3]

## References

1. **[^](#cite_ref-1)** AdisInsight [Erythropoietin gene therapy - Oxford BioMedica](http://adisinsight.springer.com/drugs/800017416) Page accessed June 5, 2016

1. ^ [***a***](#cite_ref-NYT_2-0) [***b***](#cite_ref-NYT_2-1) Gretchen Reynolds for The New York Times. June 3, 2007. [Outlaw DNA](https://www.nytimes.com/2007/06/03/sports/playmagazine/0603play-hot.html?_r=0)

1. **[^](#cite_ref-WADA_3-0)** World Anti Doping Agency. (October 2009). Gene Doping. In World Anti-Doping Agency. Retrieved April 11, 2012, from [http://www.wada-ama.org/en/Science-Medicine/Science-topics/Gene-Doping/](http://www.wada-ama.org/en/Science-Medicine/Science-topics/Gene-Doping/) [Archived](https://web.archive.org/web/20091121094012/http://www.wada-ama.org/en/Science-Medicine/Science-topics/Gene-Doping/) 2009-11-21 at the [Wayback Machine](/source/Wayback_Machine).

## Further reading

- Patrick Barry. Aug. 2, 2008 [Finding the Golden Genes](https://www.jstor.org/stable/20494726). Science News 174(3):16-21

- Yoshimi M, Maeyama T, Yamada M, Hamada N, Fukumoto J, Kawaguchi T, Kuwano K, & Nakanishi Y. (2008). Recombinant human erythropoietin reduces epithelial cell apoptosis and attenuates bleomycin-induced pneumonitis in mice. *Respirology 13*(5). 639-645.

- Percy MJ. (2008). Familial erythrocytosis arising from a gain-of-function mutation in the HIF2A gene of the oxygen sensing pathway. *Ulster Medical Journal 77*(2). 86-88.

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Adapted from the Wikipedia article [Repoxygen](https://en.wikipedia.org/wiki/Repoxygen) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/Repoxygen?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.