# Progoitrin

> Mediated Wiki article. Canonical URL: https://mediated.wiki/source/Progoitrin
> Markdown URL: https://mediated.wiki/source/Progoitrin.md
> Source: https://en.wikipedia.org/wiki/Progoitrin
> Source revision: 999475506
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{{chembox
| ImageFile = Progoitrin.svg
| ImageSize = 
| IUPACName = 
|Section1={{Chembox Identifiers
| CASNo_Ref = {{cascite|correct|??}}
| CASNo = 585-95-5 
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = S27T66W417
| PubChem = 5281139
| ChEBI = 79352
| KEGG = C08425
| SMILES =  OC[C@H]1O[C@@H](SC(C[C@@H](O)C=C)=NOS(O)(=O)=O)[C@H](O)[C@@H](O)[C@@H]1O
| StdInChI = 1S/C11H19NO10S2/c1-2-5(14)3-7(12-22-24(18,19)20)23-11-10(17)9(16)8(15)6(4-13)21-11/h2,5-6,8-11,13-17H,1,3-4H2,(H,18,19,20)/t5-,6+,8+,9-,10+,11-/m0/s1 
| StdInChIKey = MYHSVHWQEVDFQT-ILPXZUKPSA-N 
|  ChemSpiderID = 58145377

  }}
|Section2={{Chembox Properties
| Formula = C<sub>11</sub>H<sub>19</sub>NO<sub>10</sub>S<sub>2</sub>
| MolarMass = 
| Appearance =
| Density =
| MeltingPt =
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|Section3={{Chembox Hazards
| MainHazards=
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'''Progoitrin''' is a biochemical from the [glucosinolate](/source/glucosinolate) family that is found in some food, which is inactive but after ingestion is converted to [goitrin](/source/goitrin). Goitrin decreases the [thyroid hormone](/source/thyroid_hormone) production.

Progoitrin has been isolated in [cabbage](/source/cabbage), [brussels sprout](/source/brussels_sprout)s, [kale](/source/kale), [peanut](/source/peanut)s, [mustard](/source/Mustard_seed), [rutabaga](/source/rutabaga), [kohlrabi](/source/kohlrabi), [spinach](/source/spinach), [cauliflower](/source/cauliflower), [horseradish](/source/horseradish), and [rapeseed oil](/source/rapeseed_oil).<ref>Comprehensive Pharmacy Review, Leon Shargel, 6th edition, p1191.</ref>

==References==
{{reflist}}

==Bibliography==
*{{cite journal|last=Greer|first=Monte A.|title=Isolation from Rutabaga Seed of Progoitrin, the Precursor of the Naturally Occurring Antithyroid Compound, Goitrin (L-5-Vinyl-2-Thioöxazolidine)<sup>1</sup>|journal=[Journal of the American Chemical Society](/source/Journal_of_the_American_Chemical_Society)|date=20 March 1956|volume=78|issue=6|pages=1260–1261|doi=10.1021/ja01587a052}} 

Category:Glucosinolates
{{Cruciferous Biochemistry}}

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Adapted from the Wikipedia article [Progoitrin](https://en.wikipedia.org/wiki/Progoitrin) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/Progoitrin?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.