# Preproenzyme

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A '''preproenzyme''' is an [enzyme](/source/enzyme) with two additional characteristics: "pre" refers to a signal sequence ([signal peptide](/source/signal_peptide)) which directs the enzyme to a specific [organelle](/source/organelle) or subcellular localization; "pro" indicates that the enzyme is present in an inactive form and requires modification (e.g. cleavage) for activation.<ref>{{cite journal |pmid=9642203|pmc=107305|title=Secretion of elastinolytic enzymes and their propeptides by Pseudomonas aeruginosa|vauthors=Braun P, de Groot A, Bitter W, Tommassen J |year=1988|journal=J. Bacteriol.|volume=180|issue=13|pages=3467–3469|doi=10.1128/JB.180.13.3467-3469.1998 }}</ref>

==See also==
* [Protein precursor](/source/Protein_precursor)
* [Zymogen](/source/Zymogen)

==References==
{{Reflist}}

Category:Enzymes
Category:Precursor proteins

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