# Polylaminin

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**Polylaminin** or **polyLM**, is a stabilized form of [laminin](/source/Laminin), a family of natural proteins, which is being studied for use in treating [spinal cord injuries](/source/Spinal_cord_injuries) in animals and humans.[1][2][3] In early human trials, a patient with a fractured neck vertebra after a car accident had a full recovery after a year, and a chronic quadriplegic patient regained arm movement.[4][5][6] The Brazilian Academy of Neurology, [Brazilian Academy of Sciences](/source/Brazilian_Academy_of_Sciences), and the [Brazilian Society for the Progress of Science](/source/Brazilian_Society_for_the_Progress_of_Science) advise caution before clinical tests are completed.[7]

## References

1. Marques, Jairo & Pasquini, Patrícia (2025-11-09). ["Groundbreaking Brazilian Drug, Considered Capable of Reversing Spinal Cord Injury, Presented in São Paulo"](https://www1.folha.uol.com.br/internacional/en/scienceandhealth/2025/09/groundbreaking-brazilian-drug-considered-capable-of-reversing-spinal-cord-injury-presented-in-sao-paulo.shtml). [Folha de S.Paulo](/source/Folha_de_S.Paulo). Retrieved 2026-03-02.

1. Menezes, Karla & Lima, Marco Aurelio B. et al. (2024-02-21). "Return of Voluntary Motor Contraction After Complete Spinal Cord Injury: A Pilot Human Study on Polylaminin"

1. ["Brazilian scientists use placenta protein to restore some movement in dogs and humans with spinal cord injuries"](https://ensaiosclinicos.gov.br/news/331)

1. de Carvalho, Ana Luiza (2025-09-11). ["Cristália drug offers hope for quadriplegia patients"](https://valorinternational.globo.com/business/news/2025/09/10/cristalia-drug-offers-hope-for-quadriplegia-patients.ghtml). Valor International. Retrieved 2026-03-02.

1. National Cancer Institute (2023-04-04). ["The case of polylaminin in the treatment of spinal cord injuries"](https://www.youtube.com/watch?v=quYlC-uBsn0). YouTube. Retrieved 2025-10-03.

1. National Cancer Institute (2025-10-30). ["Polylaminin: The Brazilian discovery that could transform the treatment of spinal cord injuries"](https://www.youtube.com/watch?v=QcvWaG4UxAs). YouTube. Retrieved 2025-10-03.

1. Collucci, Cláudia (2026-02-24). ["Neurologists Warn of Lack of Evidence Regarding Polylaminin's Action in Spinal Cord Injury"](https://www1.folha.uol.com.br/internacional/en/scienceandhealth/2026/02/neurologists-warn-of-lack-of-evidence-regarding-polylaminins-action-in-spinal-cord-injury.shtml). Folha de S.Paulo. Retrieved 2026-03-01.

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