# Poikiloderma

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Medical condition

Poikiloderma People with varying manifestations of poikiloderma Specialty Dermatology

**Poikiloderma** is a skin condition that consists of areas of [hypopigmentation](/source/Hypopigmentation), [hyperpigmentation](/source/Hyperpigmentation), [telangiectasias](/source/Telangiectasias) and [atrophy](/source/Atrophy). Poikiloderma of Civatte is most frequently seen on the chest or the neck, characterized by red colored pigment on the skin that is commonly associated with sun damage.[1]

## Types

- [Poikiloderma vasculare atrophicans](/source/Poikiloderma_vasculare_atrophicans)

- [Poikiloderma of Civatte](/source/Poikiloderma_of_Civatte)

- [Hereditary sclerosing poikiloderma](/source/Hereditary_sclerosing_poikiloderma)

## Causes

- Congenital

1. [Rothmund-Thompson syndrome](/source/Rothmund-Thompson_syndrome)

1. [Dyskeratosis congenita](/source/Dyskeratosis_congenita)

1. [Mendes da Costa syndrome](/source/Mendes_da_Costa_syndrome)

- Other hereditary causes

1. [Degos-Touraine syndrome](/source/Degos-Touraine_syndrome)

1. Diffuse and macular atrophic [dermatosis](/source/Dermatosis)

1. [Hereditary sclerosing poikiloderma](/source/Hereditary_sclerosing_poikiloderma) of weary

1. [Kindler syndrome](/source/Kindler_syndrome)

1. [Xeroderma pigmentosum](/source/Xeroderma_pigmentosum)

- Acquired

1. Injury to cold, heat, ionizing radiation, exposure to sensitizing chemicals

1. [Lichen planus](/source/Lichen_planus)

1. [Dermatomyositis](/source/Dermatomyositis)

1. [Lupus erythematosus](/source/Lupus_erythematosus)

1. [Systemic sclerosis](/source/Systemic_sclerosis)

1. [Cutaneous T cell lymphomas](/source/Cutaneous_T_cell_lymphoma)

## Pathogenesis

The exact cause of poikiloderma of Civatte is unknown; however, extended sun exposure, namely the [ultraviolet light](/source/Ultraviolet_light) emitted by the sun, is the primary factor.[2]

## Treatment

Albeit difficult, treatment of poikiloderma of Civatte involves the delivery of multiple wavelengths of intense pulsed light (IPL) to the affected area.[3]

## See also

- [Osteopoikilosis](/source/Osteopoikilosis)

- [List of cutaneous conditions](/source/List_of_cutaneous_conditions)

- [POIKTMP syndrome](/source/Hereditary_fibrosing_poikiloderma_with_tendon_contractures%2C_myopathy%2C_and_pulmonary_fibrosis)

## References

1. **[^](#cite_ref-1)** Raulin, Christian; Karsai, Syrus (2011). [*Laser and IPL Technology in Dermatology and Aesthetic Medicine*](https://books.google.com/books?id=yY7fz5J4g4sC&q=Poikiloderma+check+neck). Springer Science & Business Media. p. 236. [ISBN](/source/ISBN_(identifier)) [9783642034381](https://en.wikipedia.org/wiki/Special:BookSources/9783642034381). Retrieved 7 March 2018.

1. **[^](#cite_ref-2)** American Osteopathic College of Dermatology ["Dermatologic Disease Database"](http://www.aocd.org/skin/dermatologic_diseases/Poikiloderma-of-Civatte.html), *aocd.org*, referenced July 22, 2011.

1. **[^](#cite_ref-3)** PubMed.gov ["Treatment of poikiloderma of Civatte with an intense pulsed light source"](https://www.ncbi.nlm.nih.gov/pubmed/11335804), *PubMed.gov*, referenced July 22, 2011.

v t e Pigmentation disorders/Dyschromia Hypo-/ leucism Loss of melanocytes Vitiligo Quadrichrome vitiligo Vitiligo ponctué Syndromic Alezzandrini syndrome Vogt–Koyanagi–Harada syndrome Melanocyte development Piebaldism Waardenburg syndrome Tietz syndrome Loss of melanin/ amelanism Albinism Oculocutaneous albinism Ocular albinism in humans Melanosome transfer Hermansky–Pudlak syndrome Chédiak–Higashi syndrome Griscelli syndrome Elejalde syndrome Griscelli syndrome type 2 Griscelli syndrome type 3 Other Cross syndrome ABCD syndrome Albinism–deafness syndrome Idiopathic guttate hypomelanosis Phylloid hypomelanosis Progressive macular hypomelanosis Leukoderma w/o hypomelanosis Vasospastic macule Woronoff's ring Nevus anemicus Ungrouped Nevus depigmentosus Postinflammatory hypopigmentation Pityriasis alba Vagabond's leukomelanoderma Yemenite deaf-blind hypopigmentation syndrome Wende–Bauckus syndrome Hyper- Melanin/ Melanosis/ Melanism Reticulated Dermatopathia pigmentosa reticularis Pigmentatio reticularis faciei et colli Reticulate acropigmentation of Kitamura Reticular pigmented anomaly of the flexures Naegeli–Franceschetti–Jadassohn syndrome Dyskeratosis congenita X-linked reticulate pigmentary disorder Galli–Galli disease Revesz syndrome Diffuse/ circumscribed Lentigo/Lentiginosis: Lentigo simplex Liver spot Centrofacial lentiginosis Generalized lentiginosis Inherited patterned lentiginosis in black persons Ink spot lentigo Lentigo maligna Mucosal lentigines Partial unilateral lentiginosis PUVA lentigines Melasma Erythema dyschromicum perstans Lichen planus pigmentosus Café au lait spot Poikiloderma (Poikiloderma of Civatte Poikiloderma vasculare atrophicans) Riehl melanosis Linear Incontinentia pigmenti Scratch dermatitis Shiitake mushroom dermatitis Other/ ungrouped Acanthosis nigricans Freckle Familial progressive hyperpigmentation Pallister–Killian syndrome Periorbital hyperpigmentation Photoleukomelanodermatitis of Kobori Postinflammatory hyperpigmentation Transient neonatal pustular melanosis Other pigments Iron Hemochromatosis Iron metallic discoloration Pigmented purpuric dermatosis Schamberg disease Majocchi's disease Gougerot–Blum syndrome Doucas and Kapetanakis pigmented purpura/Eczematid-like purpura of Doucas and Kapetanakis Lichen aureus Angioma serpiginosum Hemosiderin hyperpigmentation Other metals Argyria Chrysiasis Arsenic poisoning Lead poisoning Titanium metallic discoloration Other Carotenosis Tar melanosis Dyschromia Dyschromatosis symmetrica hereditaria Dyschromatosis universalis hereditaria See also Skin color Skin whitening Tanning Sunless Tattoo removal Depigmentation

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Adapted from the Wikipedia article [Poikiloderma](https://en.wikipedia.org/wiki/Poikiloderma) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/Poikiloderma?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.