# Peripolar cell

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{{Short description|Type of glomerular epithelial cell}}
{{More footnotes needed|date=September 2024}}
'''Peripolar cells''' are specialized [epithelial cells](/source/Epithelium). Peripolar cells are located within [Bowman's capsule](/source/Bowman's_capsule) at its [vascular pole](/source/Renal_corpuscle). These cells were discovered at the [vascular pole](/source/Renal_corpuscle) of the [sheep](/source/sheep) [glomerulus](/source/Glomerulus_(kidney)). The cells contain numerous [cytoplasmic granules](/source/Granule_(cell_biology)). The granules in peripolar cells are secretory, and the cells show features of secretory epithelial cells, although no exocytosis was observed. By secreting specific molecules, they may influence the composition of the filtrate and the reabsorption processes in the [renal tubules](/source/Nephron). There is also ongoing research that if it is part of the [juxtaglomerular apparatus](/source/juxtaglomerular_apparatus) (JGA). The number, size, and appearance of '''peripolar cells''' can vary across different mammalian species.<ref>{{Cite journal |title=The granular peripolar cell of the human glomerulus: an ultrastructural study |journal= Journal of Anatomy|date=1986 |pmc=1166522 |pmid=3693060 |last1=Gardiner |first1=D. S. |last2=More |first2=I. A. |last3=Lindop |first3=G. B. |volume=146 |pages=31–43 }}</ref><ref>{{Cite journal |title= A comparative study of the glomerular peripolar cell and the renin-secreting cell in twelve mammalian species|url=https://link.springer.com/article/10.1007/BF00327786 |journal=Cell & Tissue Research|date=1994 |doi=10.1007/BF00327786 |last1=Gibson |first1=I. W. |last2=Gardiner |first2=D. S. |last3=Downie |first3=I. |last4=Downie |first4=T. T. |last5=More |first5=I. A. R. |last6=Lindop |first6=G. B. M. |volume=277 |issue=2 |pages=385–390 |pmid=8082126 |url-access=subscription }}</ref>

== References ==
{{Reflist}}

Category:Renal physiology
Category:Cell biology
Category:Histology
Category:Nephrology

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Adapted from the Wikipedia article [Peripolar cell](https://en.wikipedia.org/wiki/Peripolar_cell) by Wikipedia contributors ([contributor history](https://en.wikipedia.org/wiki/Peripolar_cell?action=history)). Available under [Creative Commons Attribution-ShareAlike 4.0 International](https://creativecommons.org/licenses/by-sa/4.0/). Changes may have been made.